RU2002107449A - Хемосенсибилизатор - Google Patents
Хемосенсибилизатор Download PDFInfo
- Publication number
- RU2002107449A RU2002107449A RU2002107449/14A RU2002107449A RU2002107449A RU 2002107449 A RU2002107449 A RU 2002107449A RU 2002107449/14 A RU2002107449/14 A RU 2002107449/14A RU 2002107449 A RU2002107449 A RU 2002107449A RU 2002107449 A RU2002107449 A RU 2002107449A
- Authority
- RU
- Russia
- Prior art keywords
- chemosensitizer
- antimetabolites
- chemotherapeutic agent
- chemotherapeutic agents
- agent according
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (7)
1. R-1-3 бензодиоксолы в качестве хемосенсибилизатора со структурной формулой
2. Хемосенсибилизатором по п.1 может быть пиперин, в котором R представляет собой
3. Хемосенсибилизатор по пп.1 и 2, полезный при преодолении устойчивости к хемотерапевтическим агентам.
4. Хемотерапевтический агент по п.3 может быть рифампицином.
5. Хемотерапевтические агенты по п.3 могут быть антиметаболитами.
6. Антиметаболиты по п.5 могут выбираться из группы, содержащей доксорубицин, доунорубицин, винкристин, винбластин, паклитаксель, кар-боплатин, этопозид, таксотрен, топотекан, адриамицин, цисплатин, 5-фторурацил, митоксантрон, блеомицин и тому подобные.
7. Хемотерапевтический агент по п.3 может быть хлорохином.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN591MU2000 | 2000-06-28 | ||
| IN591/MUM/2000 | 2000-06-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2002107449A true RU2002107449A (ru) | 2003-11-20 |
Family
ID=11097259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2002107449/14A RU2002107449A (ru) | 2000-06-26 | 2001-06-26 | Хемосенсибилизатор |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1296682A4 (ru) |
| AP (1) | AP2002002453A0 (ru) |
| AU (1) | AU7440301A (ru) |
| EA (1) | EA005672B1 (ru) |
| RU (1) | RU2002107449A (ru) |
| WO (1) | WO2002000164A2 (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1608370A1 (en) * | 2003-03-31 | 2005-12-28 | Council of Scientific and Industrial Research | Use of cuminum cyminum extract and piperine for potention of bioeffiacy of anti infectives |
| US8580752B2 (en) * | 2005-03-31 | 2013-11-12 | Council Of Scientitic And Industrial Research | Aromatic amides as potentiators of bioefficacy of anti-infective drugs |
| AU2007264361B2 (en) | 2006-06-26 | 2013-07-18 | The University Of British Columbia | Secreted Protein Acidic and Rich in Cysteine (SPARC) as chemotherapeutic sensitizers |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0650728B1 (en) * | 1993-10-29 | 2002-02-27 | Council of Scientific and Industrial Research | Pharmaceutical compositions containing piperine and an antituberculosis or antileprosydrug |
| IN176897B (ru) * | 1993-10-29 | 1996-09-28 | Cadila Lab Ltd | |
| US5744161A (en) * | 1995-02-24 | 1998-04-28 | Sabinsa Corporation | Use of piperine as a bioavailability enhancer |
| EP0935964A1 (en) * | 1998-02-12 | 1999-08-18 | Panacea Biotec Limited | Pharmaceutical compositions containing NSAIDs and piperine |
-
2001
- 2001-06-26 RU RU2002107449/14A patent/RU2002107449A/ru not_active Application Discontinuation
- 2001-06-26 AU AU74403/01A patent/AU7440301A/en not_active Abandoned
- 2001-06-26 EA EA200200288A patent/EA005672B1/ru not_active IP Right Cessation
- 2001-06-26 AP APAP/P/2002/002453A patent/AP2002002453A0/en unknown
- 2001-06-26 WO PCT/IB2001/001133 patent/WO2002000164A2/en not_active Application Discontinuation
- 2001-06-26 EP EP01940915A patent/EP1296682A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002000164A3 (en) | 2002-10-24 |
| AU7440301A (en) | 2002-01-08 |
| EA200200288A1 (ru) | 2003-02-27 |
| EP1296682A2 (en) | 2003-04-02 |
| WO2002000164A8 (en) | 2002-05-16 |
| AP2002002453A0 (en) | 2002-06-30 |
| EP1296682A4 (en) | 2004-11-10 |
| WO2002000164A2 (en) | 2002-01-03 |
| EA005672B1 (ru) | 2005-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA94 | Acknowledgement of application withdrawn (non-payment of fees) |
Effective date: 20051014 |