RU2002107305A - Anti-inflammatory eye drops based on a broad-spectrum antibiotic and topical glucocorticoid - Google Patents

Anti-inflammatory eye drops based on a broad-spectrum antibiotic and topical glucocorticoid Download PDF

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Publication number
RU2002107305A
RU2002107305A RU2002107305/15A RU2002107305A RU2002107305A RU 2002107305 A RU2002107305 A RU 2002107305A RU 2002107305/15 A RU2002107305/15 A RU 2002107305/15A RU 2002107305 A RU2002107305 A RU 2002107305A RU 2002107305 A RU2002107305 A RU 2002107305A
Authority
RU
Russia
Prior art keywords
substances
eye drops
medium
range
contain
Prior art date
Application number
RU2002107305/15A
Other languages
Russian (ru)
Inventor
Владимир ЯНЧУШ (SK)
Владимир ЯНЧУШ
Йозеф АМБРО (SK)
Йозеф АМБРО
Елена СЛУЧАКОВА (SK)
Елена СЛУЧАКОВА
Original Assignee
Юнимед Фарма Спол. С Р.О. (Sk)
Юнимед Фарма Спол. С Р.О.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юнимед Фарма Спол. С Р.О. (Sk), Юнимед Фарма Спол. С Р.О. filed Critical Юнимед Фарма Спол. С Р.О. (Sk)
Publication of RU2002107305A publication Critical patent/RU2002107305A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Claims (4)

1. Глазные капли с антивоспалительным эффектом на основе антибиотика широкого спектра действия и глюкокортикоида местного действия, отличающиеся тем, что они содержат в качестве активных веществ азидамфеникол и дексаметазон или его фосфат или ацетат, а также консервирующую добавку, вещества, поддерживающие величину рН среды в пределах от 4,5 до 7,5, вещества, обеспечивающие вязкость среды в пределах от 5 до 25 мПа, и дистиллированную воду при следующем соотношении компонентов, мас.%:1. Eye drops with an anti-inflammatory effect based on a broad-spectrum antibiotic and topical glucocorticoid, characterized in that they contain azidamphenicol and dexamethasone or its phosphate or acetate as active substances, as well as a preservative supplement, substances that maintain the pH of the medium within from 4.5 to 7.5, substances that provide a viscosity of the medium in the range from 5 to 25 MPa, and distilled water in the following ratio of components, wt.%: Азидамфеникол 0,1-2Azidamphenicol 0.1-2 Дексаметазон или его фосфат или ацетат 0,01-1Dexamethasone or its phosphate or acetate 0.01-1 Консервирующая добавка 0,0005-0,1Preservative Additive 0.0005-0.1 Вещества, поддерживающие величину рН в пределах от 4,5 до 7,5 0,001-2Substances that support a pH in the range from 4.5 to 7.5 0.001-2 Вещества, обеспечивающие вязкость среды в пределах от 5 до 25 мПа 0,01-5Substances providing a viscosity of the medium in the range from 5 to 25 MPa 0.01-5 Дистиллированная вода Остальное до 100Distilled water Else up to 100 2. Глазные капли по п.1, отличающиеся тем, что в качестве консервирующей добавки они содержат карбетопендециниум бромид, бензалконий хлорид, тимеросал, хлорогексидин или хлоробутанол.2. Eye drops according to claim 1, characterized in that they contain carbetopendecium bromide, benzalkonium chloride, thimerosal, chlorohexidine or chlorobutanol as a preservative. 3. Глазные капли по п.1, отличающиеся тем, что в качестве веществ, поддерживающих величину рН среды в пределах от 4,5 до 7,5, капли содержат одно из следующих веществ: ацетат натрия, хлорид натрия, борную кислоту, буру, динатриевый эдетат, вторичный кислый фосфорнокислый натрий или первичный кислый фосфорнокислый натрий, или их смесь.3. Eye drops according to claim 1, characterized in that, as substances that maintain the pH of the medium in the range from 4.5 to 7.5, the drops contain one of the following substances: sodium acetate, sodium chloride, boric acid, borax, disodium edetate, secondary acidic sodium phosphate or primary acidic sodium phosphate, or a mixture thereof. 4. Глазные капли по п.1, отличающиеся тем, что в качестве веществ, обеспечивающих вязкость среды в пределах от 5 до 25 мПа, капли содержат одно из следующих веществ: гидроксипропилметилцеллюлозу, поливиниловый спирт, полиоксиэтиленсорбитанмоноолеат, или их смесь.4. Eye drops according to claim 1, characterized in that, as substances that provide a viscosity of the medium in the range from 5 to 25 MPa, the drops contain one of the following substances: hydroxypropyl methylcellulose, polyvinyl alcohol, polyoxyethylene sorbitan monooleate, or a mixture thereof.
RU2002107305/15A 2000-07-03 2001-06-25 Anti-inflammatory eye drops based on a broad-spectrum antibiotic and topical glucocorticoid RU2002107305A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SK2232000 2000-07-03
SKPUV0223-2000 2000-07-03

Publications (1)

Publication Number Publication Date
RU2002107305A true RU2002107305A (en) 2004-01-27

Family

ID=20435772

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002107305/15A RU2002107305A (en) 2000-07-03 2001-06-25 Anti-inflammatory eye drops based on a broad-spectrum antibiotic and topical glucocorticoid

Country Status (8)

Country Link
AU (1) AU2001266548A1 (en)
CZ (1) CZ12190U1 (en)
FR (1) FR2812196B3 (en)
PL (1) PL354056A1 (en)
RO (1) RO121087B1 (en)
RU (1) RU2002107305A (en)
UA (1) UA53917A (en)
WO (1) WO2002002122A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2506086C1 (en) * 2012-09-07 2014-02-10 Илья Александрович Марков Eye drops possessing antiinflammatory and antibacterial action

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2121633A2 (en) 2007-02-12 2009-11-25 Merck & Co., Inc. Piperazine derivatives for treatment of ad and related conditions
US8461389B2 (en) 2008-04-18 2013-06-11 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
RU2504372C1 (en) * 2012-09-07 2014-01-20 Илья Александрович Марков Eye drops

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56104814A (en) * 1980-01-25 1981-08-20 Kunihiro Okanoe Preparation of eye drop

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2506086C1 (en) * 2012-09-07 2014-02-10 Илья Александрович Марков Eye drops possessing antiinflammatory and antibacterial action

Also Published As

Publication number Publication date
UA53917A (en) 2003-02-17
CZ12190U1 (en) 2002-04-15
FR2812196B3 (en) 2002-06-28
AU2001266548A1 (en) 2002-01-14
WO2002002122A1 (en) 2002-01-10
FR2812196A3 (en) 2002-02-01
RO121087B1 (en) 2006-12-29
PL354056A1 (en) 2003-12-15

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Legal Events

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FA93 Acknowledgement of application withdrawn (no request for examination)

Effective date: 20010625