RU2001128504A - Growth promoting compositions - Google Patents
Growth promoting compositionsInfo
- Publication number
- RU2001128504A RU2001128504A RU2001128504/14A RU2001128504A RU2001128504A RU 2001128504 A RU2001128504 A RU 2001128504A RU 2001128504/14 A RU2001128504/14 A RU 2001128504/14A RU 2001128504 A RU2001128504 A RU 2001128504A RU 2001128504 A RU2001128504 A RU 2001128504A
- Authority
- RU
- Russia
- Prior art keywords
- inhibitor
- dipeptidyl peptidase
- dwarfism
- composition
- pharmaceutical composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 7
- 230000012010 growth Effects 0.000 title claims 2
- 230000001737 promoting Effects 0.000 title 1
- 239000003603 dipeptidyl peptidase IV inhibitor Substances 0.000 claims 6
- 206010013883 Dwarfism Diseases 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 230000017423 tissue regeneration Effects 0.000 claims 3
- 230000003111 delayed Effects 0.000 claims 2
- 230000018109 developmental process Effects 0.000 claims 2
- 102000018997 Growth Hormone Human genes 0.000 claims 1
- 108010051696 Growth Hormone Proteins 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000000122 growth hormone Substances 0.000 claims 1
- 150000002825 nitriles Chemical class 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- 230000004936 stimulating Effects 0.000 claims 1
- 230000036435 stunted growth Effects 0.000 claims 1
- 230000001225 therapeutic Effects 0.000 claims 1
Claims (10)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9906715.9 | 1999-03-23 | ||
GBGB9906715.9A GB9906715D0 (en) | 1999-03-23 | 1999-03-23 | Compositions for promoting growth |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2001128504A true RU2001128504A (en) | 2003-06-27 |
RU2242228C2 RU2242228C2 (en) | 2004-12-20 |
Family
ID=10850230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2001128504/15A RU2242228C2 (en) | 1999-03-23 | 2000-03-21 | Growth-stimulating composition |
Country Status (26)
Country | Link |
---|---|
US (1) | US6521644B1 (en) |
EP (1) | EP1171121B1 (en) |
JP (1) | JP2002539244A (en) |
KR (1) | KR100704348B1 (en) |
CN (1) | CN1359293A (en) |
AR (1) | AR023130A1 (en) |
AT (1) | ATE297728T1 (en) |
AU (1) | AU772421B2 (en) |
CA (1) | CA2366926A1 (en) |
CZ (1) | CZ20013411A3 (en) |
DE (1) | DE60020825T2 (en) |
GB (1) | GB9906715D0 (en) |
HK (1) | HK1048589A1 (en) |
HU (1) | HUP0200391A3 (en) |
IL (2) | IL145568A0 (en) |
MX (1) | MXPA01009610A (en) |
MY (1) | MY124214A (en) |
NO (1) | NO20014608L (en) |
NZ (1) | NZ514450A (en) |
PL (1) | PL195529B1 (en) |
RU (1) | RU2242228C2 (en) |
TR (1) | TR200102648T2 (en) |
TW (1) | TWI239246B (en) |
UA (1) | UA73115C2 (en) |
WO (1) | WO2000056297A2 (en) |
ZA (1) | ZA200108082B (en) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040152745A1 (en) * | 1999-11-12 | 2004-08-05 | Guilford Pharmaceuticals, Inc. | Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors |
GB9928330D0 (en) | 1999-11-30 | 2000-01-26 | Ferring Bv | Novel antidiabetic agents |
US6395767B2 (en) | 2000-03-10 | 2002-05-28 | Bristol-Myers Squibb Company | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method |
JP4300108B2 (en) * | 2001-06-27 | 2009-07-22 | スミスクライン ビーチャム コーポレーション | Pyrrolidines as dipeptidyl peptidase inhibitors |
UA74912C2 (en) | 2001-07-06 | 2006-02-15 | Merck & Co Inc | Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes |
CA2508487A1 (en) * | 2002-12-04 | 2004-06-17 | Merck & Co., Inc. | Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
CA2518465A1 (en) * | 2003-03-25 | 2004-10-14 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
EP1625122A1 (en) | 2003-05-14 | 2006-02-15 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
CN1867560A (en) * | 2003-08-13 | 2006-11-22 | 武田药品工株式会社 | 4-pyrimidone derivatives and their use as peptidyl peptidase inhibitors |
EP1697342A2 (en) * | 2003-09-08 | 2006-09-06 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
EP1699777B1 (en) * | 2003-09-08 | 2012-12-12 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
UA85871C2 (en) * | 2004-03-15 | 2009-03-10 | Такеда Фармасьютікал Компані Лімітед | Dipeptidyl peptidase inhibitors |
WO2005118555A1 (en) * | 2004-06-04 | 2005-12-15 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
US7872124B2 (en) * | 2004-12-21 | 2011-01-18 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
DOP2006000008A (en) | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | COMBINED THERAPY FOR THE TREATMENT OF DIABETES AND RELATED AFFECTIONS AND FOR THE TREATMENT OF AFFECTIONS THAT IMPROVE THROUGH AN INCREASE IN THE BLOOD CONCENTRATION OF GLP-1 |
CA2599419A1 (en) * | 2005-04-22 | 2006-11-02 | Alantos Pharmaceuticals Holding, Inc. | Dipeptidyl peptidase-iv inhibitors |
CN102908350B (en) * | 2005-09-14 | 2014-07-23 | 武田药品工业株式会社 | Dipeptidyl peptidase inhibitors for treating diabetes |
NZ566799A (en) | 2005-09-14 | 2011-04-29 | Takeda Pharmaceutical | Dipeptidyl peptidase inhibitors for treating diabetes |
US20070060529A1 (en) * | 2005-09-14 | 2007-03-15 | Christopher Ronald J | Administration of dipeptidyl peptidase inhibitors |
TW200745079A (en) * | 2005-09-16 | 2007-12-16 | Takeda Pharmaceuticals Co | Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor |
WO2007035629A2 (en) | 2005-09-16 | 2007-03-29 | Takeda Pharmaceutical Company Limited | Process for the preparation of pyrimidinedione derivatives |
TW200745080A (en) * | 2005-09-16 | 2007-12-16 | Takeda Pharmaceuticals Co | Polymorphs of tartrate salt of 2-[2-(3-(R)-amino-piperidin-1-yl)-5-fluoro-6-oxo-6H-pyrimidin-1-ylmethyl]-benzonitrile and methods of use therefor |
WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
EP1999108A1 (en) * | 2006-03-28 | 2008-12-10 | Takeda Pharmaceutical Company Limited | Preparation of (r)-3-aminopiperidine dihydrochloride |
PE20071221A1 (en) | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | GPR119 RECEPTOR AGONISTS IN METHODS TO INCREASE BONE MASS AND TO TREAT OSTEOPOROSIS AND OTHER CONDITIONS CHARACTERIZED BY LOW BONE MASS, AND COMBINED THERAPY RELATED TO THESE AGONISTS |
SI2073810T1 (en) * | 2006-09-13 | 2011-12-30 | Takeda Pharmaceutical | Use of 2-6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl-4-fluoro-benzonitrile for treating diabetes, cancer, autoimmune disorders and hiv infection |
US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
TW200838536A (en) * | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
EP2146210A1 (en) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY |
JO2870B1 (en) | 2008-11-13 | 2015-03-15 | ميرك شارب اند دوهم كورب | Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
AR077642A1 (en) | 2009-07-09 | 2011-09-14 | Arena Pharm Inc | METABOLISM MODULATORS AND THE TREATMENT OF DISORDERS RELATED TO THE SAME |
EP2473047B1 (en) | 2009-09-02 | 2014-08-13 | Merck Sharp & Dohme Corp. | Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
JP5540454B2 (en) | 2009-12-30 | 2014-07-02 | シャンハイ フォチョン ファーマシューティカル カンパニー リミテッド | Dipeptidyl peptidase inhibitor |
EP2538783B1 (en) | 2010-02-22 | 2016-06-01 | Merck Sharp & Dohme Corp. | Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes |
EP2556056A1 (en) | 2010-04-06 | 2013-02-13 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2011146358A1 (en) | 2010-05-21 | 2011-11-24 | Merck Sharp & Dohme Corp. | Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes |
KR101871011B1 (en) | 2010-09-22 | 2018-06-25 | 아레나 파마슈티칼스, 인크. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012135570A1 (en) | 2011-04-01 | 2012-10-04 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012145361A1 (en) | 2011-04-19 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012145603A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012145604A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012170702A1 (en) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2013055910A1 (en) | 2011-10-12 | 2013-04-18 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
EP2814485A4 (en) | 2012-02-17 | 2015-08-26 | Merck Sharp & Dohme | Dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
EP2874622A4 (en) | 2012-07-23 | 2015-12-30 | Merck Sharp & Dohme | Treating diabetes with dipeptidyl peptidase-iv inhibitors |
WO2014074668A1 (en) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulators of gpr119 and the treatment of disorders related thereto |
EA201791982A1 (en) | 2015-03-09 | 2020-02-17 | Интекрин Терапьютикс, Инк. | METHODS FOR TREATING A NON-ALCOHOLIC FAT LIVER DISEASE AND / OR LIPODYSTROPHY |
CN110996951A (en) | 2017-04-03 | 2020-04-10 | 科赫罗斯生物科学股份有限公司 | PPAR gamma agonists for the treatment of progressive supranuclear palsy |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05508624A (en) | 1990-04-14 | 1993-12-02 | ニュー イングランド メデカル センター ホスピタルズ インク | Dipeptidyl-aminopeptidase type 4 inhibitor |
WO1992008481A1 (en) * | 1990-11-14 | 1992-05-29 | The Upjohn Company | Stabilized, potent grf analogs |
JPH0543453A (en) * | 1991-08-20 | 1993-02-23 | Sumitomo Pharmaceut Co Ltd | Local sustained-release preparation for accelerating wound curing |
HUT67319A (en) * | 1991-08-30 | 1995-03-28 | Life Medical Sciences Inc | Compositions for treating wounds |
DK0610317T3 (en) * | 1991-10-22 | 2001-02-19 | New England Medical Center Inc | Inhibitors of dipeptidyl aminopeptidase type IV |
IL111785A0 (en) * | 1993-12-03 | 1995-01-24 | Ferring Bv | Dp-iv inhibitors and pharmaceutical compositions containing them |
JPH09295946A (en) * | 1995-05-16 | 1997-11-18 | Mitsui Pharmaceut Inc | Medicine composition |
JPH09308259A (en) * | 1996-05-17 | 1997-11-28 | Toshiba Lighting & Technol Corp | Power supply, discharge lamp lighting apparatus and lighting apparatus |
TW492957B (en) * | 1996-11-07 | 2002-07-01 | Novartis Ag | N-substituted 2-cyanopyrrolidnes |
US5952301A (en) | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
-
1999
- 1999-03-23 GB GBGB9906715.9A patent/GB9906715D0/en not_active Ceased
-
2000
- 2000-03-21 DE DE60020825T patent/DE60020825T2/en not_active Expired - Fee Related
- 2000-03-21 AU AU33186/00A patent/AU772421B2/en not_active Ceased
- 2000-03-21 PL PL00350796A patent/PL195529B1/en unknown
- 2000-03-21 MY MYPI20001117A patent/MY124214A/en unknown
- 2000-03-21 WO PCT/IB2000/000393 patent/WO2000056297A2/en not_active Application Discontinuation
- 2000-03-21 CN CN00805326A patent/CN1359293A/en active Pending
- 2000-03-21 RU RU2001128504/15A patent/RU2242228C2/en not_active IP Right Cessation
- 2000-03-21 HU HU0200391A patent/HUP0200391A3/en unknown
- 2000-03-21 NZ NZ514450A patent/NZ514450A/en unknown
- 2000-03-21 MX MXPA01009610A patent/MXPA01009610A/en active IP Right Grant
- 2000-03-21 AT AT00911195T patent/ATE297728T1/en not_active IP Right Cessation
- 2000-03-21 UA UA2001096487A patent/UA73115C2/en unknown
- 2000-03-21 TR TR2001/02648T patent/TR200102648T2/en unknown
- 2000-03-21 JP JP2000606202A patent/JP2002539244A/en active Pending
- 2000-03-21 US US09/937,031 patent/US6521644B1/en not_active Expired - Fee Related
- 2000-03-21 KR KR1020017012145A patent/KR100704348B1/en not_active IP Right Cessation
- 2000-03-21 CA CA002366926A patent/CA2366926A1/en not_active Abandoned
- 2000-03-21 EP EP00911195A patent/EP1171121B1/en not_active Expired - Lifetime
- 2000-03-21 IL IL14556800A patent/IL145568A0/en active IP Right Grant
- 2000-03-21 CZ CZ20013411A patent/CZ20013411A3/en unknown
- 2000-03-22 AR ARP000101281A patent/AR023130A1/en unknown
- 2000-03-23 TW TW089105321A patent/TWI239246B/en not_active IP Right Cessation
-
2001
- 2001-09-21 NO NO20014608A patent/NO20014608L/en not_active Application Discontinuation
- 2001-09-23 IL IL145568A patent/IL145568A/en unknown
- 2001-10-02 ZA ZA200108082A patent/ZA200108082B/en unknown
-
2002
- 2002-11-29 HK HK02108644.1A patent/HK1048589A1/en unknown
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