RU2001105041A - METHOD FOR DIAGNOSTICS OF REDUCED RELIABILITY OF MUSCULAR TRANSMISSION - Google Patents

METHOD FOR DIAGNOSTICS OF REDUCED RELIABILITY OF MUSCULAR TRANSMISSION

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Publication number
RU2001105041A
RU2001105041A RU2001105041/14A RU2001105041A RU2001105041A RU 2001105041 A RU2001105041 A RU 2001105041A RU 2001105041/14 A RU2001105041/14 A RU 2001105041/14A RU 2001105041 A RU2001105041 A RU 2001105041A RU 2001105041 A RU2001105041 A RU 2001105041A
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RU
Russia
Prior art keywords
decrease
values
reliability
neuromuscular transmission
omega
Prior art date
Application number
RU2001105041/14A
Other languages
Russian (ru)
Other versions
RU2214162C2 (en
Inventor
Игорь Борисович Заболотских
Людмила Николаевна Антипова
Original Assignee
Игорь Борисович Заболотских
Людмила Николаевна Антипова
Российский центр функциональной хиругической гастроэнтерологии
Filing date
Publication date
Application filed by Игорь Борисович Заболотских, Людмила Николаевна Антипова, Российский центр функциональной хиругической гастроэнтерологии filed Critical Игорь Борисович Заболотских
Priority to RU2001105041/14A priority Critical patent/RU2214162C2/en
Priority claimed from RU2001105041/14A external-priority patent/RU2214162C2/en
Publication of RU2001105041A publication Critical patent/RU2001105041A/en
Application granted granted Critical
Publication of RU2214162C2 publication Critical patent/RU2214162C2/en

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Claims (1)

Способ диагностики снижения надежности нервно-мышечной передачи, отличающийся тем, что у больного предварительно определяют фоновые значения омега-потенциала (ω1), затем - максимальное отклонение омега-потнециала (ω2) в первые 5 с активации мышц тенара во время произвольной задержки дыхания на максимальном вдохе, по разнице ω2-ω1 выявляют интенсивность отклонения омега-потенциала Δω, и при условии значений Δω менее -4 мВ определяют нормальную нервно-мышечную передачу; при значениях Δω от 3 мВ до 0 мВ определяют группу риска с дефицитом возбуждения скелетной мышцы синаптической и/или супрасинаптической природы; а при Δω более +1 мВ определяют снижение надежности нервно-мышечной передачи, тяжесть которой, сопоставимую с данными декремент-теста (Д), определяют по формуле:
Д(%) = -10+(-2,13×Δω),
причем уменьшение значений Д по данным омегаметрии пропорционально степени снижения надежности нервно-мышечной передачи.A method for diagnosing a decrease in the reliability of neuromuscular transmission, characterized in that the patient first determines the background values of the omega potential (ω 1 ), then the maximum deviation of omega pottium (ω 2 ) in the first 5 seconds of activation of the tenar muscles during an arbitrary breath hold at the maximum breath, the difference ω 2 -ω 1 reveals the intensity of the deviation of the omega-potential Δω, and under the condition of values Δω less than -4 mV, determine the normal neuromuscular transmission; with Δω values from 3 mV to 0 mV, a risk group with a deficit of excitation of skeletal muscle of a synaptic and / or suprasynaptic nature is determined; and when Δω is more than +1 mV, a decrease in the reliability of neuromuscular transmission is determined, the severity of which is comparable with the decrement test data (D) is determined by the formula:
D (%) = -10 + (- 2,13 × Δω),
moreover, the decrease in the values of D according to omegametry is proportional to the degree of decrease in the reliability of neuromuscular transmission.
RU2001105041/14A 2001-02-22 2001-02-22 Method for diagnosing neuromuscular transmission reduction RU2214162C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2001105041/14A RU2214162C2 (en) 2001-02-22 2001-02-22 Method for diagnosing neuromuscular transmission reduction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2001105041/14A RU2214162C2 (en) 2001-02-22 2001-02-22 Method for diagnosing neuromuscular transmission reduction

Publications (2)

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RU2001105041A true RU2001105041A (en) 2002-12-27
RU2214162C2 RU2214162C2 (en) 2003-10-20

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RU (1) RU2214162C2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2511080C1 (en) * 2013-03-13 2014-04-10 Федеральное государственное бюджетное учреждение "Научный центр неврологии" Российской академии медицинских наук (ФГБУ "НЦН" РАМН) Method for prediction of crisis in patients with myasthenia
RU2612820C1 (en) * 2016-01-11 2017-03-13 Федеральное бюджетное учреждение науки "Уфимский научно-исследовательский институт медицины труда и экологии человека" Method for diagnosis of neuromuscular disorders stages due to functional overload for agricultural workers based on stimulus electroneuromyography indicators

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