The utility model relates to the field of medicine, namely to medical equipment for inhalation of a rat, bypassing direct contact of a laboratory assistant with a rat and injected gas.
As a result of the patent information search, a similar utility model / patent No. 177360, publ. 02/19/2018, bull. No. 5 / "Inhaler for laboratory animals with an adjustable level of supply of the active substance." The “inhaler” consists of 3 containers made of transparent plastic, hermetically and sequentially connected to each other, the first of which contains the acting substance and is connected by means of a supply tube having a ball valve and a shutter to a volumetric lid mounted above the exhaust fan with a potentiometer of the second container chamber for experimental animals, which, by means of a pipe installed in the side hole, is connected to the third container - a detoxification chamber, which also has openings on the side surface A hole with an exhaust fan with a potentiometer installed in it, while on the side of the last chamber opposite the fan there is a hose for the release of carbon dioxide and oxygen, and on the front surface of the second container there is a hole with gaskets for the rat's neck and an operating field in front of it. The disadvantages of this utility model are as follows. Firstly, the pads are a good fixer only for rats with a neck of a certain diameter, because of this, it is necessary to change components for different types of rat neck, which imposes certain time and material costs on the researcher. Secondly, the shutters in the tube 3 are an inefficient source of oxygen for the chamber with the test animal due to the lack of an active oxygen injection system. Thirdly, to control the supply of the active substance, the researcher must simultaneously control the fan rotation power for supplying the substance and the opening / closing of the ball valve, which creates some inconvenience during operation with the “Inhaler”.
The technical problem that this utility model is aimed at is the creation of an automatic inhaler for small animals, which allows not only inhalation, bypassing contact with the laboratory assistant with the animals during manipulations with them, but also automatically adjust the supply level and the degree of release of the substance, oxygen, as well as the ability to customize the size of the hole for individual morphometric characteristics of the neck of animals without unnecessary components.
The essence of the utility model is that in an automatic inhaler for laboratory animals, which includes three containers of transparent plastic, hermetically and sequentially interconnected, the first of which contains the active substance and is connected via a pipe to the second container through an exhaust fan in its upper part, wherein the hole in the side of the second container is connected via a pipe through an exhaust fan to a third container having, on the opposite fan, a side There is a pipe for the exit of carbon dioxide and oxygen, on the front surface of the second container in its lower part there is an opening for the neck of the animal and in front of it is an operating table, a fan and an opening valve are installed in the pipe connecting the first and second containers, on the front wall of the second container - a nozzle with an air cylinder for the possibility of regulating the size of the holes for the neck of the animal, and on its back side there is a fan for oxygen supply, the inhaler has two tumblers with the possibility of installation in belts, one of which is located on the second container and has the ability to simultaneously turn on / off the fan in the pipe and the exhaust fan of the second container, the second toggle switch is mounted on the third container and has the ability to simultaneously turn on / off the fan for oxygen supply and the exhaust fan of the third container, while all fans with potentiometers, and in the third container, carbon dioxide and oxygen are cleaned with a sorbent.
The utility model is illustrated by the figure - FIG. 1- General view of the installation. An automatic inhaler for laboratory animals consists of a first container - a reservoir 1 with an active substance 2, a pipe 3 with a fan 4 and a valve 5 installed in it; the fan is switched on through the toggle switch 6, mounted on the second container - a chamber for experimental animals 7, with an exhaust fan 8 on the upper wall, a fan for oxygen supply on the back wall 9, and a nozzle 10 in the lower part with an opening whose size is adjustable with the help of a cylinder 11, which is filled with air, and with an operating table 12 attached in this place; the container 7 is connected by a pipe 13 to a third container - a detoxification chamber 14, having a toggle switch 15 on the side that regulates the operation of the fans 9 and 16 (exhaust fan), on the opposite side - a pipe 17 through which carbon dioxide and oxygen come out, purified from the existing substances using adsorbent 18.
Work with the device as follows. The tank 1 is filled with inhalation substance 2. The laboratory animal is placed on the operating table 12 so that the animal’s neck is at the level of the nozzle 10, then the researcher adjusts the diameter of the neck opening, the researcher turns on the toggle switch 6, which starts the rotation of fan 4, which opens valve 5 and feeds pipe 3 active substance 2, and the rotation of the exhaust fan 8, which transfers the active substance 2 to the experimental chamber 7. After sufficient accumulated in the experimental chamber 7 The amount of active substance, the researcher through the toggle switch 15 starts the oxygen supply fan 9 located on the rear wall of the chamber 7, and the exhaust fan 16, which is located at the entrance of the pipe 13 to the detoxification chamber 14, and provides a mixture of oxygen, carbon dioxide and active substance into the detoxification chamber 14. For all fans of the inhalation system, the researcher can adjust the number of fan blades revolutions per minute (from 0.25 to 0.125 ml / s) through potentiometers connected to each th fan. Further, the researcher can carry out various manipulations on the surgical field 12. At the end of the experiment, the researcher turns off the toggle switch 6, as a result of which the active substance 2 is stopped, but when the toggle switch 15 is turned on, the oxygen supply continues, which ensures a quick return of the laboratory animal to its original state.
To expand the functionality, the toggle switch 6 provides the simultaneous start of the fans 4 and 8, and the toggle switch 15 - the fans 9 and 16. At the same time, each toggle switch has the ability to initially set the fan operation time, which generally facilitates the work with the device.
The technical result from the use of a utility model is to automate the inhalation process of a laboratory animal using a system for monitoring the level of oxygen and active substance during the study, providing conditions for the absence of toxic substances on the experimenter’s body, while the possibility of substances on the experimenter’s body, while the possibility of surgical operations on the body of an experimental animal and the possibility of adjusting the size of the opening tia for individual morphometric characteristics of the neck of the animal.
With the simplicity of the design solution, the device has universality: it can use various gases, different animals (rats, guinea pigs, hamsters), you can adjust the level of supply of the active substance and oxygen in an active way (using fans). The advantages of an automatic inhaler for laboratory animals are, firstly, the low cost of the design, which allows you to change and transform it in accordance with the number of rats and the chemical nature of the substance. The second advantage of an automatic inhaler is the ability to pre-set the time frame for the operation of the fans, which creates a certain automation of work with the inhalation system.