RU182802U1 - Pulse wave contour analysis device - Google Patents

Pulse wave contour analysis device Download PDF

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RU182802U1
RU182802U1 RU2018107019U RU2018107019U RU182802U1 RU 182802 U1 RU182802 U1 RU 182802U1 RU 2018107019 U RU2018107019 U RU 2018107019U RU 2018107019 U RU2018107019 U RU 2018107019U RU 182802 U1 RU182802 U1 RU 182802U1
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input
signal
derivative
output
divider
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RU2018107019U
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Russian (ru)
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Анастасия Николаевна Маркина
Александр Александрович Федотов
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федеральное государственное автономное образовательное учреждение высшего образования "Самарский национальный исследовательский университет имени академика С.П. Королева"
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0295Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography

Abstract

The device relates to medical equipment, namely to devices for non-invasive registration of biosignals based on the use of photoplethysmography methods. This device can be used in early patient diagnosis systems for monitoring heart rate, assessing the status of peripheral arterial vessels. The pulse wave contour analysis apparatus comprises a pulse generator, a light source, a photodetector, a current / voltage converter, an alternating voltage amplifier, a synchronous demodulator, a bandpass filter, an analog-to-digital converter, a microcontroller, a unit for calculating a first derivative of a signal, a unit for calculating a second derivative of a signal, three Root mean square block, three divisors. The device allows to evaluate the functional state of human arterial vessels based on non-invasive registration and processing of the pulse wave signal and calculating the shape factor of the pulse wave circuit. 1 ill.

Description

The device relates to medical equipment, namely to devices for non-invasive registration of biosignals based on the use of photoplethysmography methods. This device can be used in early patient diagnosis systems for monitoring heart rate, assessing the status of peripheral arterial vessels.

The registration and processing of pulse wave signals is widely used in instrumental systems of cardiological diagnostics, including for non-invasive assessment of hemodynamic processes in the arterial bed of a person. One of the most clinically effective and universal methods for registering a pulse wave is photoplethysmography.

A device for photoplethysmography (photoplethysmograph) is known (Patent RU 2354290, IPC А61В 5/0295, А61В 5/1455, published May 10, 2009), including a pulse generator, a light source, a synchronous selective amplifier, a low-pass filter, a photodetector, a synchronous demodulator, a bandpass filter, controlled voltage / current converter and pulse distributor.

A disadvantage of the known device is the inability to assess the functional state of peripheral arterial vessels due to the lack of specialized pulse wave signal processing units.

Closest to the proposed device is a device for recording arterial pulsation of blood (Patent RU IPC 2536282, A61B 5/0295, A61B 5/1455, published December 20, 2014), including a pulse generator, a light source, a photodetector, a current / voltage converter, an alternating current amplifier voltage, synchronous demodulator, band-pass filter, analog-to-digital converter, microcontroller, subtraction unit, adaptive filter, accelerometer.

A disadvantage of the known device is the lack of functionality for diagnosing the condition of human peripheral arterial vessels, which leads to a decrease in the efficiency of using the device in cardiology diagnostics.

The utility model is based on the task of developing a pulse wave signal recording device that allows a direct assessment of the functional state of peripheral arterial vessels based on calculating the shape factor of the pulse wave contour (PM Rangayyan. Analysis of biomedical signals. Practical approach. M .: Fizmatlit, 2007. 233 - 235 p.).

The technical result of the development is to increase the efficiency of diagnosing the state of human arterial vessels and expand the functionality of the devices for registering arterial pulsations of blood.

The problem is solved due to the fact that the device for contour analysis of a pulse wave, containing a pulse generator, a light source, a photodetector, a current / voltage converter, a synchronous demodulator, an alternating voltage amplifier, a bandpass filter, an analog-to-digital converter, a microcontroller, according to a utility model , the device further includes a unit for calculating a first derivative of a signal, a unit for calculating a second derivative of a signal, three units for calculating a standard deviation, three dividers, By the way, the output of the microcontroller is connected to the input of the first unit of calculation of the standard deviation and simultaneously to the input of the unit of calculation of the first derivative of the signal, the output of the unit of calculation of the first derivative of the signal is connected to the input of the second unit of calculation of the standard deviation and simultaneously to the input of the unit of calculation of the second derivative of the signal, the output of the second derivative of the calculation unit the signal is connected to the input of the third unit of calculation of the standard deviation, the output of the first unit of calculation of the mean the squared deviation is connected to the first input of the first divider, the output of the second standard deviation calculation unit is connected to the second input of the first divider and simultaneously to the first input of the second divider, the output of the third standard deviation calculation unit is connected to the second input of the second divider, the output of the first divider is connected to the first input of the third divider, the output of the second divider is connected to the second input of the third divider.

Thanks to the changes and additions described above, it becomes possible to implement an algorithm for assessing the functional state of human arterial vessels based on the calculation of the shape factor FF:

Figure 00000001

where: σ x is the standard deviation of the initial pulse wave signal, σ x ' is the standard deviation of the first derivative of the pulse wave signal, σ x' is the standard deviation of the second derivative of the pulse wave.

The utility model is illustrated in the drawing, which shows a structural diagram of the proposed device for contour analysis of a pulse wave.

A device for the contour analysis of a pulse wave contains the following blocks: a pulse generator 1, a light source 2, a photodetector 3, a current / voltage converter 4, an AC amplifier 5, a synchronous demodulator 6, a bandpass filter 7, an analog-to-digital converter 8, a microcontroller 9, the first the standard deviation calculation unit 10, the first derivative calculation unit of the signal 11, the second standard deviation calculation unit 12, the second derivative calculation unit of the signal 13, the third standard deviation calculation unit atichnogo deviation 14, the first divider 15, second divider 16, the third divider 17. The light source 2 and the photodetector 3 are made as a single type photoplethysmographic sensor clamp 18.

In the scheme, the light source 2 is controlled by current pulses generated in the pulse generator 1, the radiation from the light source 2 enters the area of biological tissue containing an arterial vessel. The radiation passing through the biological tissue is fed to the photodetector 3, the output of the photodetector 3 is connected to the input of the current-voltage converter 4, the output of the current-voltage converter 4 is connected to the input of the alternating voltage amplifier 5, the output of the alternating voltage amplifier 5 is connected to the input of the synchronous demodulator 6, the output of the synchronous demodulator 6 is connected to the input of the bandpass filter 7, the output of the bandpass filter 7 is connected to the input of the analog-to-digital converter 8, the output of the analog-to-digital converter 8 is connected to an ode to the microcontroller 9, the output of the microcontroller 9 is connected to the input of the first standard deviation calculation unit 10 and to the input of the first derivative calculation unit 11, the output of the first derivative calculation unit is connected to the input of the second standard deviation calculation unit 12 and simultaneously to the input of the second derivative calculation unit 13, output the second derivative calculation unit is connected to the input of the third standard deviation calculation unit 14, the output of the first standard deviation calculation unit 10 is connected to the first input of the first divider 15, the output of the second standard deviation calculation unit 12 is connected to the second input of the first divider 15 and simultaneously to the first input of the second divider 16, the output of the third standard deviation calculation unit 14 is connected to the second input of the second divider 16, the output of the first the divider 15 is connected to the first input of the third divider 17, the output of the second divider 16 is connected to the second input of the third divider 17.

The device operates as follows.

The light source 2 is controlled by rectangular current pulses generated in the pulse generator 1, the radiation from the light source 2 enters the area of biological tissue containing an arterial vessel. The radiation transmitted through biological tissues is fed to photodetector 3. Photodetector 3 converts the radiation attenuated by biological tissues into a photo current, which is then converted into voltage using a current / voltage converter 4, and the resulting voltage is fed to an alternating voltage amplifier 5, from which an amplified signal is input synchronous demodulator 6, where the envelope of the pulse wave signal is extracted, from the output of the synchronous demodulator 6, the signal enters the band-pass filter 7 to select the variable component of arterial pulsation of the blood, as well as to filter the present noise and interference. Then the alternating pulse wave signal is fed to the input of the analog-to-digital converter 8, where quantization and sampling of the recorded biosignal takes place. The data from the output of the analog-to-digital converter 8 is supplied to the microcontroller 9, then the samples of the recorded pulse wave biosignal are received from the output of the microcontroller 9 to the input of the first unit of calculation of the standard deviation 10, where the standard deviation of the initial signal of the pulse wave σ x is determined, and at the same time the signal samples are sent to the input of the calculation unit of the first derivative of the signal 11. The samples of the first derivative of the signal from the output of the calculation unit of the first derivative of the signal 11 are input of the second standard deviation calculation unit 12, where the standard deviation of the first derivative of the pulse wave signal σ x ' is determined, and simultaneously the samples of the first derivative of the signal are fed to the input of the second derivative of the signal 13. The samples of the second derivative of the signal from the output of the second derivative of the signal 13 are sent to the input of the third standard deviation calculation unit 14, where the standard deviation of the second derivative of the pulse wave signal σ x ″ is determined. Then, the data from the output of the first standard deviation calculation unit 10 goes to the first input of the first divider 15, the data of the second standard deviation calculation unit 12 goes to the second input of the first divider 15, where the ratio σ x ' / σ x is calculated and simultaneously to the first input of the second divider 16 , the data from the output of the third block of the mean quadratic estimate 14 is fed to the second input of the second divider 16, where the ratio σ x ' / σ x вычис is calculated. The received data from the first divider 15 is fed to the first input of the third divider 17, the data from the output of the second divider 16 is fed to the second input of the third divider 17, where the form factor FF is calculated.

The introduction of new elements (the unit for calculating the first derivative, the unit for calculating the second derivative, three units for calculating the standard deviation of the estimate, three divisors) and their relationship allow us to evaluate the functional state of human arterial vessels based on the calculation of the shape factor FF:

Figure 00000002

where: σ x is the standard deviation of the original pulse wave signal, σ x ' is the standard deviation of the first derivative of the pulse wave signal, σ x' is the standard deviation of the second derivative of the pulse wave.

Claims (1)

  1. A device for contour analysis of a pulse wave containing a pulse generator, a light source, a photodetector, a current / voltage converter, an alternating voltage amplifier, a synchronous demodulator, a bandpass filter, characterized in that the device further includes a unit for calculating a first derivative of a signal, a unit for calculating a second derivative of a signal, three blocks for calculating the standard deviation, three dividers, and the output of the microcontroller is connected to the input of the first block for calculating the standard deviation and simultaneously to the input of the calculation unit of the first derivative of the signal, the output of the calculation unit of the first derivative of the signal is connected to the input of the second unit of calculation of the standard deviation and at the same time to the input of the calculation unit of the second derivative of the signal, the output of the calculation unit of the second derivative of the signal is connected to the input of the third unit of calculation of the standard deviation, the output of the first standard deviation calculation unit is connected to the first input of the first divider, the output of the second medium calculation unit nonquadratic deviation connected to the second input of the first divider and simultaneously to a first input of the second divider, a third output of block standard deviation calculating connected to the second input of the second divider output of the first divider is connected to the first input of the third divider, the output of the second divider is connected to the second input of the third divider.
RU2018107019U 2018-02-26 2018-02-26 Pulse wave contour analysis device RU182802U1 (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU69393U1 (en) * 2007-07-11 2007-12-27 Закрытое акционерное общество "ОКБ "РИТМ" Photo playmismograph
WO2014043613A1 (en) * 2012-09-14 2014-03-20 Covidien Lp System and method for determining stability of cardiac output
RU2536282C2 (en) * 2013-03-12 2014-12-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный аэрокосмический университет имени академика С.П. Королева (национальный исследовательский университет)" (СГАУ) Arterial blood pulsation recorder
US9380952B2 (en) * 2010-12-28 2016-07-05 Sotera Wireless, Inc. Body-worn system for continuous, noninvasive measurement of cardiac output, stroke volume, cardiac power, and blood pressure
CA2991235A1 (en) * 2015-07-01 2017-01-05 Everist Genomics, Inc. System and method of assessing endothelial function
WO2017100185A1 (en) * 2015-12-07 2017-06-15 Medici Technologies, LLC Observational heart failure monitoring system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU69393U1 (en) * 2007-07-11 2007-12-27 Закрытое акционерное общество "ОКБ "РИТМ" Photo playmismograph
US9380952B2 (en) * 2010-12-28 2016-07-05 Sotera Wireless, Inc. Body-worn system for continuous, noninvasive measurement of cardiac output, stroke volume, cardiac power, and blood pressure
WO2014043613A1 (en) * 2012-09-14 2014-03-20 Covidien Lp System and method for determining stability of cardiac output
RU2536282C2 (en) * 2013-03-12 2014-12-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный аэрокосмический университет имени академика С.П. Королева (национальный исследовательский университет)" (СГАУ) Arterial blood pulsation recorder
CA2991235A1 (en) * 2015-07-01 2017-01-05 Everist Genomics, Inc. System and method of assessing endothelial function
WO2017100185A1 (en) * 2015-12-07 2017-06-15 Medici Technologies, LLC Observational heart failure monitoring system

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