RU1819612C - Method of treatment and prophylaxis of bartonellosis in calves - Google Patents

Abstract

Usage: in veterinary medicine, in particular in veterinary microbiology, immunology and episiotiology of bodies of bodies of the invention. Summary of the invention: the method involves the introduction of bodies of the drug there, including, wt.%: Azidine 5-7, trichopol 10-12, chloramphenicol 10-12, furatsillin 10-12. 1- 2% aqueous solution of sodium carboxymethyl cellulose or 15-25% aqueous solution of polyvinylpyrrolidone a - up to 100. The indicated composition is administered orally at a dose of 5 ml (based on 8-10 mg of azidine per 1 kg of live weight calf) immediately after birth and for 2–3 consecutive days. An additional 50-70 ml of iodinol is also administered intravenously immediately after birth and for 2–3 consecutive days.

Description

The invention relates to the field of veterinary medicine and, in particular, relates to veterinary microbiology, immunology and epizootology.

The aim of the invention is to find the most effective method for the treatment and prevention of calf bartonellosis.

The essence of the invention lies in the fact that for this purpose, chloramphenicol is administered as an antibiotic in the bodies and, in addition, azidine, Trichopolum, is administered. furatsillin, 1-2% aqueous solution of sodium carboxymethyl cellulose or 15-25% aqueous solution of polyvinylpyrrolidone in the following ratio, wt.%:

Azidine 5-7

Trichopolum, chloramphenicol,

furatsillin po 10-12

A 1-2% aqueous solution of carboxymethyl cellulose sodium salt or a 15-25% aqueous solution of polyvinylpyrrolidone is the rest; moreover, this mixture is administered orally in a dose of 5 ml (from

calculating 8-10 mg of azidine per 1 kg of calf live weight) immediately after birth for 2-3 days; 50-70 ml of iodinol are also additionally administered intravenously immediately after birth and for 2–3 consecutive days.

Examples of the method.

The work was carried out at the farm to them. M. Dadazhanova, Dustlik district, Jizzakh region, Uzbek SSR.

Three series of experiments were performed to treat and prevent calf bartonellosis.

Experiment 1. Bodies there immediately after birth, the following mixture (suspension) was orally administered, in a ratio of components, wt.%:

Azidine7 Trichopolum and furatsillin 12.5 Chloramphenicol 10 1.5% aqueous solution of sodium salt of carboxymethyl cellulose - the rest. Initially, 20 bodies there, immediately after birth, 3 ml of this mixture were evaporated,

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once a day for 2-3 days (5-7 mg mg / kg of pure azidine).

As a result, diarrhea was observed in 5 out of 20 calves, which had to be treated with acetic acid by oral administration in a dose of 1 g per 2 liters of milk - for each booze for 3-5 days.

Another group of calves (20 goals) immediately after birth was given this suspension of 5 ml (8-10 mg / kg of pure azidine) once a day for 2-3 days.

As a result, not a single calf fell ill with bartonellosis.

To the third group of bodies t (20 goals) immediately after calving .. 6 ml (10-14 mg / kg of azidine) were drunk into this mixture, 2-3 days a day.

All bodies remained alive and healthy.

Thus, the optimal suspension dose is 1.5-2 ml for every 10 kg of calf live weight or 8-10 mg of pure azidine, which was prevented by 90 calves. All bodies remained alive and healthy. Moreover, not a single calf had secondary bronchopneumonia, which affected almost all newborn calves before using the drug. The minimum effective dose was 1 ml per 10 kg of live weight of the calf, the maximum was 2-2.5 ml.

Experiment 2. Bodies there immediately after calving, iodinol was administered intravenously (via a dropper) (three groups of 20 animals).

The first group received iodinol 25–40 ml each, the second 50–70 ml each and a third 75–100 ml each.

As a result, in the first group 12 bodies of t fell ill (diarrhea), in the second - 4 and in the third 5 t.

All diseased bodies were treated with a suspension, which was given by mouth once a day for 2-3 days.

As a result, 4 calves fell in the first group, and 1 in the others.

Thus, the minimum effective dose of iodinol for intravenous administration is 1 ml per 1 kg of live weight

calf, maximum - 2.5-3 mg / kg, optimal - 2 ml / kg.

Experiment 3. 20 bodies there immediately after calving, a suspension of 1.5-2 was given inside.

ml / 10 kg, and iodinol was administered intravenously at 2-2.5 ml / kg for 2-3 days.

As a result, 100% safety of newborn bodies was observed.

Therefore, the best results

in the treatment and prevention of bartonellosis, telts were obtained with the combined use of complex polymer sous-. azidine suspensions and simultaneous intravenous administration of iodinol.

The use of the invention will allow to maintain the maximum number of nascent young farm animals and prevent them from respiratory and other diseases than

Claims (1)

it is possible to intensify livestock production with an increase in productivity and a significant reduction in the cost of livestock products. The claims A method for the treatment and prophylaxis of calf baronellosis, comprising administering antibiotics, characterized in that, in order to increase the effectiveness of the method, chloramphenicol and additionally aaidine, trichopolum, furatsillin, 1-2% are administered as antibiotics an aqueous solution of the sodium salt of carboxymethylcellulose or a 15-25% aqueous solution of polyvinylpyrrolidone in the following ratio of components, wt.%: azidine 5-7; Trichopolum 10-12; chloramphenicol 10-12; furatsillin 10-12; 1-2% aqueous solution of sodium carboxymethyl cellulose or 15-25% aqueous solution polyvinylpyrrolidone the rest, and the specified mixture is administered orally at a dose of 5 ml (based on 8-10 mg of azidine per 1 kg of calf live weight) immediately after birth and for 2-3 subsequent days, and 50-70 ml of iodinol is also additionally administered intravenously immediately after birth and for 2–3 consecutive days.