RU173456U1 - DEVICE FOR TRANSDERMAL LOCAL AND / OR INHALATION ADMINISTRATION OF BIOLOGICALLY ACTIVE SUBSTANCES (GATE) - Google Patents

Abstract

The utility model relates both to hygiene products and to medicine, and in particular to devices or devices for applying media, for example, hygiene products, drugs to the skin, as well as to simple inhalation devices with activated or ionized gases (vapors) obtained by evaporation impregnated with a specific composition (hygienic, medicinal products containing organic active ingredients that can evaporate on contact with human skin) the surface of the material from which manuf ustroystvo.Predlagaemoe this solution completely abolishes the process of sewing podvorotnichka, which is used in a variety of law enforcement agencies in the field uniforms. The rejection of the traditional use of sewn-in collars will reduce the time for replacing the collar and a certain amount of material means for attaching it (material, threads, needles). The use of this technical solution eliminates the trauma of the fingers of the hands with a skid of pathogens and the development of suppuration. New is the attachment of Velcro to the collar of the clothes and to the device itself, as well as impregnation of the collar, depending on the goals and objectives, with various substances (tonic, soothing, analgesic, repelling (repellents) or their combinations).

Description

The utility model relates both to hygiene products and to the field of medicine, namely to devices or devices for applying drugs, for example, drugs, to the skin, as well as to simple inhalation devices with activated gases (vapors) obtained by evaporation by heating in contact with human skin impregnated with a specific composition (hygienic or medicinal products containing biological active ingredients capable of evaporation when in contact with human skin) on top spine of the material from which the device is manufactured.

A biologically active substance can be a means for painkillers, antihypertensives, tranquilizing purposes.

In various types and branches of the Armed Forces, special units in the field form of clothing, it is traditionally accepted to use sewn (standard and home-made) white cotton door-leaves, replaced as they become soiled (as a rule, at least once a day in normal life). The neck area is a powerful reflexogenic zone (the so-called “collar”). The proximity of the aortic and sinocarotid reflexogenic zones enhances the importance of this area in the regulation of cardiovascular reactions and the general tone of the body. The issue of provision, washing, reuse, disposal is not yet fully resolved. Under certain conditions, unmasking parking lots and determining the number of personnel is important.

The process of sewing on the collar requires certain material means (material, thread, needle), skills and time - about 15 minutes in a calm environment (15 minutes × 365 days = 5475 minutes, which is more than 90 hours or 3.8 days a year).

In the process of suturing the collar, it is possible to injure fingers of the hands with a skid of pathogens and the development of suppuration (panaritium, phlegmon, sepsis, etc.), often requiring long-term inpatient treatment, and in some cases this can lead to disability (with loss of the distal phalanx of the second finger right hand conclusion of the military-medical commission "Not fit for military service").

One of the methods for introducing chemicals, including drugs into the human body, is the transdermal administration method.

It consists in providing direct contact of substances with human skin, their penetration through the skin into the blood, delivery to all organs of the human body and specific effects on them.

The term "transdermal" is used here as a generic term referring to the passage of a substance through the layers of the skin. The term “transdermal” refers to the delivery of a substance (eg, a therapeutic substance, such as a drug) through the skin to a local area of the skin or into the circulatory system without dissecting with a surgical scalpel or pricking the skin with a hypodermic needle. Transdermal delivery of a substance involves delivery by passive diffusion. When drugs spread both through the stratum corneum and through the epidermis, the rate of diffusion through the stratum corneum is often a limiting step. Compared to injections, transdermal delivery of the substance eliminates the associated pain and the possibility of infection.

Known GATE (RF patent No. 151910 U1), relating to hygiene products, in particular to means of protecting the skin of the neck from exposure to coarse uniform fabric.

The collar is designed to be worn on the collar of the uniform of servicemen of the Ministry of Defense and other departments using uniforms.

The collar consists of a calico-type fabric with buttons sewn on it for fastening to the collar of a soldier’s clothing (for this purpose, loops corresponding to the collar buttons must be cut in the clothing collar). The second part is bent to the first part from the side opposite the buttons, and is adjacent to the neck of a person wearing a uniform.

The disadvantage of this product is the complexity of the manufacture of the collar, which consists in the fact that it is necessary to sew buttons, which, although they make it possible to replace the collar, but complicate the design, making it bulky. Therefore, it is necessary to make eyelets in the collar of the uniform. Installing the gateway into the hinges of the gate is also a certain complexity and can take considerable time. With repeated use of the collar, buttons complicate the washing process, can be torn off, and their repeated sewing and the use of threads and needles lead to the expenditure of material resources and can lead to injury.

Known QUICKLY REVERSIBLE GATE (BSP) (RF patent No. 88517 U1). It consists of a base and a cover for fastening on the collar of the jacket with the help of "Velcro". The base is made of hard fabric material with the rigid parts of Velcro sewn onto it, and the cover in the shape of the base is made of woven material. On the back side of the cover there are five holes matching the five hard parts sewn on the base, and in the lower part there is an opening intended for laying the foundation.

Disadvantages of BSP

BSP consists of a base and a cover that are mounted on the collar of a field jacket with Velcro. The Velcro fastened on the collar are parts of Velcro with a size of 20 × 20 mm, which cannot ensure reliable attachment of the collar and, moreover, its adjustment left-right (up-down) along the collar. Also, the design of the BSP provides for the sewing of the cord, which complicates both the manufacture and use of the collar.

The proposed technical solution eliminates these disadvantages.

The objectives of the claimed technical solution are as follows:

- leveling of negative consequences and ensuring an increased comfortable state of a person carrying out specific actions;

- convenience for the implementation of domestic, life processes, subjecting the product to the nature of the tasks performed and comfort when performing active movements;

- the possibility of repeated use in the adoption by the units of various power structures and the organization of centralized washing and re-impregnation with active substances.

The design of a quick-change gate of industrial manufacture is proposed. The standard sizes of the gateways (Table 1) for various sizes of the gate: 1 - 36-38 cm, 2 - 39-41 cm, 3 - 42-45 cm. Dimensions of the combined elements of the contact tape, referred to in the ordinary as “Velcro”: 23 (25 ) mm by 20 (22) mm (7 pcs.), evenly distributed along the length of the gateway, at the corners of the gateway one element of a similar size is fixed. The fabric used is a thin cotton jersey of green color or camouflage colors, folded in half and stitched.

Velcro “loop” elements (Velcro braid) of 23 (25) mm by 20 (22) mm (7 pcs.) In size are fastened to the clothes collar and 1 element each is fastened to the edge of the collar, which makes it possible to quickly and safely injure the collar. Used cotton threads, 9 additions, glossy green.

It is proposed to use Velcro tape (standard contact tape), which is rigidly attached to the garment collar (sewn during the industrial production of clothes or manually onto earlier clothing samples), and a self-adhesive contact tape, which is a high-quality textile fastener of the hook and loop ”with adhesive applied to the base for fixing the collar (you just need to remove the protective tape and press on the fastener at the place of gluing on the collar). Self-adhesive tape is suitable for most surfaces, provides reliability and durability of the connection, high holding force, serves as a complete replacement for mechanical fasteners (sewing, etc.). For its fastening to the product element, there is no need to use special equipment, which eliminates many labor-intensive operations. These types of braids can be subjected to repeated washing, heat treatment without loss of properties.

In FIG. 1 shows a General view of the proposed device, in FIG. 2 - a pattern of a collar, in FIG. 3 - an example of an assembly drawing of the proposed device, FIG. Figures 4 and 5 show photographs with options for using the gateway at KPO (set of field uniforms) and VKPO (all-season set of field uniforms).

The collar proposed above, depending on the goals and objectives, can be impregnated with various substances (tonic, soothing, analgesic, repelling (repellents) or their combinations). Organofluorine compounds that can be inhaled, instilled in the eyes, nose, or drink are currently known. Having high penetrating ability, these substances, forming active complexes with molecules of other compounds, have a cumulative pharmacological effect (for example, almost instantly overcoming drowsiness, improving performance, increasing visual acuity by 20-40%), which will persist for several hours. Organofluorine compounds, released from the gateway tissue and from the human body in its original form through the skin and lungs, are an insurmountable barrier to mosquitoes and other blood-sucking insects (possibly ticks). Another active principle can be permethrin (Permethrin) - an altered enzyme (biocatalyst) of chrysanthemum with strong insecticidal activity (effective for combating insects and ticks, the so-called “hot paws” effect is noted). Material impregnated with this compound is safe for humans and does not lose its protective properties even after 100 washings (according to the information press center of the Bundeswehr Medical Service, Munich) [Military Medical Journal. 2011. No4. S. 78].

If necessary, when performing special events, the effect of exposure can be enhanced. One common way to enhance the passive transdermal diffusion flow of drugs is to pre-treat the skin with a substance that penetrates through the skin or delivers it along with the drug.

Organization of manufacture, impregnation, labeling, and hermetic packaging of gateways with various target recipes can be carried out centrally and delivered to various formations, institutions on request and for free sale.

Different types of gateways can significantly improve the quality of work performed by rescuers, fishermen, and reduce accident rate due to the human factor of drivers at night.

Getting the material and manufacturing the product is also not very difficult. One can cite as an example the "Method for producing textile material containing indomethacin" described in the patent of the Russian Federation No. 20144087. Its scope is the production of textile materials containing indomethacin, which may find application in medicine as transdermal agents. The invention consists in the following: a cellulosic textile material is treated with an aqueous solution of indomethacin, which additionally contains gelatin and dimethyl sulfoxide.

Thus, a useful model can be implemented in many variations that a person skilled in the art can deduce from the above description. All such variations and modifications are covered by the scope and essence of the utility model.

Claims (13)

1. Quick-release tissue gateway for transdermal local and / or inhalation administration of biologically active substances containing several layers and Velcro fasteners, evenly distributed along the length of the collar, while the collar is saturated with a biologically active substance. 2. Quick-detachable fabric collar according to claim 1, characterized in that biologically active impregnating substance includes means for painkillers, hypotensive, tranquilizing goals. 3. Quick-detachable fabric collar according to claim 1, characterized in that biologically active impregnating substance can secrete repellents capable of scare away blood-sucking insects. 4. Quick-detachable fabric collar according to claim 1, characterized in that the inner and outer layers are saturated with substances of various pharmacological directionality.

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