RS59967B1 - Semisolid self-microemulsifying drug delivery systems with acyclovir filled in hard capsules, their preparation and application - Google Patents
Semisolid self-microemulsifying drug delivery systems with acyclovir filled in hard capsules, their preparation and applicationInfo
- Publication number
- RS59967B1 RS59967B1 RS20170527A RSP20170527A RS59967B1 RS 59967 B1 RS59967 B1 RS 59967B1 RS 20170527 A RS20170527 A RS 20170527A RS P20170527 A RSP20170527 A RS P20170527A RS 59967 B1 RS59967 B1 RS 59967B1
- Authority
- RS
- Serbia
- Prior art keywords
- acyclovir
- filled
- self
- semisolid
- preparation
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
<p>The invention relates to the production of semi-solid self-microemulsifying systems with an acyclovir filled in hard (two-part) capsules of size 0, which have physico-chemical and biopharmaceutical characteristics of pharmaceutical preparations for oral administration with modified release acyclovir, which is preferably a precondition for improving the absorption of the active substance. The semi-solid self-microemulsifying systems of the invention in addition to acyclovir (2% -33.33%) contain: oil (medium long chain triglycerides) (5% -10%), surfactant (surfactant type macrogolglycerol hydroxystearate) (5% -40%), a cosurfactant (an active ingredient of polyglycerol esters) (2% -20%) and a hydrophilic coating agent (polyol) (10% to 30%). The invention also provides the procedures for obtaining them.</p>
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RS20170527A RS59967B1 (en) | 2017-05-25 | 2017-05-25 | Semisolid self-microemulsifying drug delivery systems with acyclovir filled in hard capsules, their preparation and application |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RS20170527A RS59967B1 (en) | 2017-05-25 | 2017-05-25 | Semisolid self-microemulsifying drug delivery systems with acyclovir filled in hard capsules, their preparation and application |
Publications (2)
Publication Number | Publication Date |
---|---|
RS20170527A1 RS20170527A1 (en) | 2018-11-30 |
RS59967B1 true RS59967B1 (en) | 2020-03-31 |
Family
ID=64558271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20170527A RS59967B1 (en) | 2017-05-25 | 2017-05-25 | Semisolid self-microemulsifying drug delivery systems with acyclovir filled in hard capsules, their preparation and application |
Country Status (1)
Country | Link |
---|---|
RS (1) | RS59967B1 (en) |
-
2017
- 2017-05-25 RS RS20170527A patent/RS59967B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
RS20170527A1 (en) | 2018-11-30 |
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