RS59358B1 - Nukleotid dims0-150 za upotrebu u tretmanu hroničnog aktivnog ulcerativnog kolitisa - Google Patents

Nukleotid dims0-150 za upotrebu u tretmanu hroničnog aktivnog ulcerativnog kolitisa

Info

Publication number
RS59358B1
RS59358B1 RSP20191190A RS59358B1 RS 59358 B1 RS59358 B1 RS 59358B1 RS P20191190 A RSP20191190 A RS P20191190A RS 59358 B1 RS59358 B1 RS 59358B1
Authority
RS
Serbia
Prior art keywords
dims0
nucleotide
treatment
ulcerative colitis
chronic active
Prior art date
Application number
Other languages
English (en)
Inventor
Charlotte Admyre
Arezou Zargari
Stein Oliver Von
Stein Petra Von
Original Assignee
Index Pharmaceuticals Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Index Pharmaceuticals Ab filed Critical Index Pharmaceuticals Ab
Publication of RS59358B1 publication Critical patent/RS59358B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/17Immunomodulatory nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/315Phosphorothioates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/31Combination therapy
RSP20191190 2011-11-25 2012-11-23 Nukleotid dims0-150 za upotrebu u tretmanu hroničnog aktivnog ulcerativnog kolitisa RS59358B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP11190826.5A EP2596806A1 (en) 2011-11-25 2011-11-25 Method for prevention of colectomy
US201261595230P 2012-02-06 2012-02-06
EP12790904.2A EP2782602B1 (en) 2011-11-25 2012-11-23 Nucleotide DIMS0-150 for use in the treatment of chronic active ulcerative colitis
PCT/EP2012/073501 WO2013076262A1 (en) 2011-11-25 2012-11-23 Method for prevention of colectomy

Publications (1)

Publication Number Publication Date
RS59358B1 true RS59358B1 (sr) 2019-11-29

Family

ID=45094516

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP20191190 RS59358B1 (sr) 2011-11-25 2012-11-23 Nukleotid dims0-150 za upotrebu u tretmanu hroničnog aktivnog ulcerativnog kolitisa

Country Status (15)

Country Link
US (3) US9492516B2 (sr)
EP (3) EP2596806A1 (sr)
JP (2) JP6193248B2 (sr)
CA (1) CA2892203C (sr)
CY (1) CY1122089T1 (sr)
DK (1) DK2782602T3 (sr)
ES (1) ES2745677T3 (sr)
HR (1) HRP20191723T1 (sr)
HU (1) HUE046154T2 (sr)
LT (1) LT2782602T (sr)
PL (1) PL2782602T3 (sr)
PT (1) PT2782602T (sr)
RS (1) RS59358B1 (sr)
SI (1) SI2782602T1 (sr)
WO (1) WO2013076262A1 (sr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2879349B1 (en) * 2013-07-05 2022-06-29 Saturn Licensing LLC Transmission device, transmission method, reception device and reception method
EP4035659A1 (en) 2016-11-29 2022-08-03 PureTech LYT, Inc. Exosomes for delivery of therapeutic agents
IL269970B (en) 2017-04-14 2022-09-01 Tallac Therapeutics Inc Polynucleotides that modulate the immune system, their antibody binding, and methods of using them
GB201707503D0 (en) * 2017-05-10 2017-06-21 Index Pharmaceuticals Ab New Therapy 3
GB201707501D0 (en) * 2017-05-10 2017-06-21 Index Pharmaceuticals Ab New therapy 2
GB201807312D0 (en) * 2018-05-03 2018-06-20 Index Pharmaceuticals Ab Formulation
GB201818579D0 (en) * 2018-11-14 2018-12-26 Index Pharmaceuticals Ab New therapy
GB201912191D0 (en) * 2019-08-24 2019-10-09 Index Pharmaceuticals Ab New therapy

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149797A (en) 1990-02-15 1992-09-22 The Worcester Foundation For Experimental Biology Method of site-specific alteration of rna and production of encoded polypeptides
EP0468520A3 (en) 1990-07-27 1992-07-01 Mitsui Toatsu Chemicals, Inc. Immunostimulatory remedies containing palindromic dna sequences
US5849719A (en) 1993-08-26 1998-12-15 The Regents Of The University Of California Method for treating allergic lung disease
ES2366201T3 (es) 1994-07-15 2011-10-18 University Of Iowa Research Foundation Oligonucleótidos inmunmoduladores.
DE69739515D1 (de) 1996-01-30 2009-09-10 Univ California Expressionsvektoren, die eine antigen-spezifische immunantwort induzieren, und methoden für ihre verwendung.
ES2241042T3 (es) 1996-10-11 2005-10-16 The Regents Of The University Of California Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora.
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
US6426334B1 (en) 1997-04-30 2002-07-30 Hybridon, Inc. Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal
ATE370740T1 (de) 1997-05-20 2007-09-15 Ottawa Health Research Inst Verfahren zur herstellung von nukleinsäurekonstrukten
US6809193B2 (en) * 1997-08-13 2004-10-26 Isis Pharmaceuticals, Inc. Antisense oligonucleotide compositions and methods for the modulation of JNK proteins
US7914990B2 (en) 2005-01-13 2011-03-29 Progenika Biopharma, S.A. Methods and products for in vitro genotyping
WO2006132204A1 (ja) * 2005-06-06 2006-12-14 Anges Mg, Inc. 転写因子デコイ
DK2269622T3 (en) 2005-07-01 2014-03-24 Index Pharmaceuticals Ab CPG OLIGONUCLEOTIDES USED TO INCREASE STEROID ACTIVITY OF A STEROID DEPENDENT PATIENT
DK2179737T3 (da) 2005-07-01 2013-11-11 Index Pharmaceuticals Ab Modulering af respons på steroider
WO2010053435A2 (en) * 2008-11-04 2010-05-14 Index Pharmaceuticals Ab Compounds and methods for the treatment of inflammatory diseases of the cns

Also Published As

Publication number Publication date
EP2782602B1 (en) 2019-06-26
US9795627B2 (en) 2017-10-24
EP2596806A1 (en) 2013-05-29
JP2015504438A (ja) 2015-02-12
PL2782602T3 (pl) 2019-12-31
CY1122089T1 (el) 2020-11-25
HUE046154T2 (hu) 2020-02-28
JP2017061508A (ja) 2017-03-30
US20150004187A1 (en) 2015-01-01
CA2892203C (en) 2021-11-16
LT2782602T (lt) 2019-10-10
ES2745677T3 (es) 2020-03-03
JP6193248B2 (ja) 2017-09-06
JP6318221B2 (ja) 2018-04-25
HRP20191723T1 (hr) 2019-12-13
DK2782602T3 (da) 2019-09-30
EP3556403A1 (en) 2019-10-23
US20180015117A1 (en) 2018-01-18
CA2892203A1 (en) 2013-05-30
EP2782602A1 (en) 2014-10-01
PT2782602T (pt) 2019-10-14
US20170014442A1 (en) 2017-01-19
US9492516B2 (en) 2016-11-15
SI2782602T1 (sl) 2019-11-29
WO2013076262A1 (en) 2013-05-30

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