Jedinjenje formule (I):X1 je ugljenik;svaki X2 i X3 je nezavisno izabran između ugljenika ili azota, tako da najmanje jedan od X1-X3predstavlja azot:X4 predstavlja CR3 ili azot;X5 predstavlja CR6, azot ili C=O;uz uslov da više od tri X1-X5 ne predstavljaju azot;- - - - - - predstavlja jednostruku ili dvostruku vezu, tako da je najmanje jedna veza u 5-članom prstenastom sistemu dvostruka veza;R3 predstavlja vodonik, halogenC1-6 alkil, C2-6 alkenil, C2-6 alkinil, C1-6 alkoksi, C3-6 cikloalkil, C3-6 cikloalkenil, cijano, haloC1-6 alkil, haloC1-6 alkoksi ili =O;A predstavlja fenil ili piridinil grupu koja može biti opciono supstituisana sa jednom ili više (npr. 1, 2 ili 3) Ra grupa;B predstavlja -V-karbocikličnu grupu ili -W-heterociklil grupu, pri čemu pomenute karbociklične i heterociklil grupe mogu biti opciono supstituisane sa jednom ili više (npr. 1, 2 ili 3) Ra grupa;R2 predstavlja aril ili heterociklil grupu, pri čemu pomenute aril i heterociklil grupe mogu biti opciono supstituisane sa jednom ili više Rb grupa;R6 predstavlja halogen, vodonik, C1-6 alkil, C1-6 alkoksi, C2-6 alkenil, C2-6 alkinil, - C=N, C3-8 cikloalkil, C3-8cikloalkenil, -NHSO2Rw, -CH=N-ORw, aril ili heterociklil grupu, pri čemu pomenute C1-6 alkil, C2-6 alkenil, C2-6 alkinil, aril i heterociklil grupe mogu biti opciono supstituisane sa jednom ili više Rb grupa; Re, Rf i Rw nezavisno predstavljaju vodonik ili C1-6 alkil;Ra predstavlja halogen, C1-6 alkil, C2-6 alkenil, C2-6 alkinil, C3-8 cikloalkil, C3-8 cikloalkenil, -ORX, -(CH2)n-O-C1-6 alkil, -O-(CH2)n-ORx, halo C1-6 alkil, halo C1-6 alkoksi, C1-6 alkanol, =O, =S, nitro, Si(Rx)4, -(CH2)S-CN, -S-Rx, -SO-Rx, -SO2-Rx, - CORX, -(CRxRy)s-COORz, -(CH2)s-CONRxRy, -(CH2)s-NRxRy, -(CH2)s-NRxCORy, -(CH2)s-NRxSO2-Ry, -(CH2)s-NH-SO2-NRxRy, -OCONRxRy, -(CH2)s-NRxCO2Ry, -O-(CH2)s-CRxRy-(CH2)t-ORz ili -(CH2)s-SO2NRxRy grupe;Rx, Ry i Rz nezavisno predstavljaju vodonik, C1-6 alkil, C2-6 alkenil, C2-6 alkinil, C1-6 alkanol, hidroksi, C1-6 alkoksi, haloC1-6 alkil, -CO-(CH2)n- C1-6 alkoksi, C3-8 cikloalkil ili C3-8 cikloalkenil;R1 i Rb nezavisno predstavljaju Ra grupu ili -Y-karbociklil ili -Z-heterociklil grupu, pri čemu pomenute karbocikli! i heterociklil grupe mogu biti opciono supstituisane sa jednom ili više (npr. 1, 2 ili 3) Ra grupa;V i W nezavisno predstavljaju vezu ili -(CReRf)n- grupu:Y i Z nezavisno predstavljaju vezu, -CO-(CH2)s-, -COO-, -(CH2)n-, -NRx-(CH2)n-, -(CH2)n-NRx-, -CONRx-, -NRxCO-, -SO2NRx-, -NRxSO2-, -NRxCONRy-, - NRxCSNRy- -O-(CH2)s-, -(CH2)s-O-, -S-, -SO- ili -(CH2)s-SO2-;n predstavlja ceo broj od 1-4; s i t nezavisno predstavljaju ceo broj od 0-4;q predstavlja ceo broj od 0-2;ili njegova farmaceutski prihvatljiva so ili solvat.Prijava sadrži još 14 patentnih zahteva.Compound of Formula (I): X1 is carbon; each X2 and X3 is independently selected from carbon or nitrogen such that at least one of X1-X3 represents nitrogen: X4 represents CR3 or nitrogen; X5 represents CR6, nitrogen or C = O; that more than three X1-X5 do not represent nitrogen; - - - - - - represent a single or double bond, such that at least one bond in the 5-membered ring system is a double bond; R3 represents hydrogen, halogenC1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxy, C3-6 cycloalkyl, C3-6 cycloalkenyl, cyano, haloC1-6 alkyl, haloC1-6 alkoxy or = O; A represents a phenyl or pyridinyl group optionally substituted by one or more (e.g., 1, 2 or 3) Ra group; B represents a -V-carbocyclic group or -W-heterocyclyl group, said carbocyclic and heterocyclyl groups being optionally substituted by one or more (e.g. 1, 2 or 3) R a group; R 2 represents an aryl or heterocyclyl group, wherein said aryl and heterocyclyl groups may optionally be substituted with one or more Rb groups; R6 represents halogen, hydrogen, C1-6 alkyl, C1-6 alkoxy, C2-6 alkenyl, C2-6 alkynyl, - C = N, C3-8 cycloalkyl, C3-8cycloalkenyl, -NHSO2Rw , -CH = N-ORw, aryl or heterocyclyl group, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl and heterocyclyl groups may be optionally substituted by one or more Rb groups; Re, Rf and Rw independently represent hydrogen or C1-6 alkyl; Ra represents halogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-8 cycloalkyl, C3-8 cycloalkenyl, -ORX, - (CH2) nO-C1-6 alkyl, -O- (CH2) n-ORx, halo C1-6 alkyl, halo C1-6 alkoxy, C1-6 alkanol, = O, = S, nitro, Si (Rx) 4, - ( CH2) S-CN, -S-Rx, -SO-Rx, -SO2-Rx, - CORX, - (CRxRy) s-COORz, - (CH2) s-CONRxRy, - (CH2) s-NRxRy, - ( CH2) s-NRxCORy, - (CH2) s-NRxSO2-Ry, - (CH2) s-NH-SO2-NRxRy, -OCONRxRy, - (CH2) s-NRxCO2Ry, -O- (CH2) s-CRxRy- ( CH2) t-ORz or - (CH2) s-SO2NRxRy groups; Rx, Ry and Rz independently represent hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkanol, hydroxy, C1-6 alkoxy , haloC1-6 alkyl, -CO- (CH2) n-C1-6 alkoxy, C3-8 cycloalkyl or C3-8 cycloalkenyl; R1 and Rb independently represent a Ra group or a -Y-carbocyclyl or -Z-heterocyclyl group, wherein said carbocycles! and heterocyclyl groups may be optionally substituted by one or more (e.g., 1, 2 or 3) Ra groups; V and W independently represent a bond or - (CReRf) n- group: Y and Z independently represent a bond, -CO- (CH 2 ) s-, -COO-, - (CH2) n-, -NRx- (CH2) n-, - (CH2) n-NRx-, -CONRx-, -NRxCO-, -SO2NRx-, -NRxSO2-, - NRxCONRy-, - NRxCSNRy- -O- (CH2) s-, - (CH2) sO-, -S-, -SO- or - (CH2) s-SO2-; n represents an integer of 1-4; s and t independently represent an integer of 0-4; q represents an integer of 0-2; or a pharmaceutically acceptable salt or solvate thereof. The application contains 14 more claims.