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Priority to YU20050953ApriorityCriticalpatent/RS52202B/en
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Publication of RS52202BpublicationCriticalpatent/RS52202B/en
Postupak za dobijanje supstituisanih ariloksi-2,3-epoksipropana opšte formule (1)gde je Ar naftil, supstituisani naitil. fenilalkil, naznačen time, što sejedinjenje opšte formule (1) dobija reagovanjem odgovarajućeg nukleofilnog anjona, dobijenog od arilhidroksi jedinjenja u prisustvu vodenog rastvora natrijum ili kalijum hidroksida na povišenoj temperaturi, sa epihlorhidrinom pri uslovima semi kontinualne ili kontinualne reakcije u vodenoj fazi.Prijava sadrži još 8 patentnih zahteva.A process for the preparation of substituted aryloxy-2,3-epoxypropane of the general formula (1) wherein Ar is naphthyl, substituted nautyl. phenylalkyl, wherein the compound of general formula (1) is obtained by reacting the corresponding nucleophilic anion obtained from an arylhydroxy compound in the presence of an aqueous solution of sodium or potassium hydroxide at elevated temperature, with epichlorohydrin under conditions of semi-continuous or continuous reaction in a semi-continuous or continuous reaction. 8 patent claims.
YU20050953A2005-12-232005-12-23Process for preparation of substituted aryloxy -2,3-epoxypropane
RS52202B
(en)
New process for the synthesis of 1,3-dihydro-2h-3-benzazepin-2-one compounds, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid.