RS51686B - Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor - Google Patents
Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitorInfo
- Publication number
- RS51686B RS51686B YU20050761A YUP76105A RS51686B RS 51686 B RS51686 B RS 51686B YU 20050761 A YU20050761 A YU 20050761A YU P76105 A YUP76105 A YU P76105A RS 51686 B RS51686 B RS 51686B
- Authority
- RS
- Serbia
- Prior art keywords
- tnf
- therapy
- patient
- inadequate response
- autoimmune disease
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- AIDS & HIV (AREA)
- Biomedical Technology (AREA)
Abstract
Upotreba antitela u proizvodnji leka za lečenje reumatoidnog artritisa davanjem dve doze antitela od 1000 mg čoveku koji ima neadekvatni odgovor na inhibitor TNFa, gde je prva doza davana 1. dana lečenja, a druga doza 15. dana, gde je antitelo rituksimab, i gde je inhibitor TNFa etanercept, infliksimab i adalimumab.Prijava sadrži još 4 patentna zahteva.Use of antibodies in the manufacture of a medicament for the treatment of rheumatoid arthritis by administering two doses of 1000 mg of antibody to a human having an inadequate response to a TNFα inhibitor, where the first dose is given on day 1 of treatment and the second dose on day 15, where the antibody is rituximab TNFα inhibitor etanercept, infliximab and adalimumab. The application contains 4 more claims.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46148103P | 2003-04-09 | 2003-04-09 | |
PCT/US2004/010509 WO2004091657A2 (en) | 2003-04-09 | 2004-04-06 | Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor |
Publications (2)
Publication Number | Publication Date |
---|---|
RS20050761A RS20050761A (en) | 2007-11-15 |
RS51686B true RS51686B (en) | 2011-10-31 |
Family
ID=33299824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU20050761A RS51686B (en) | 2003-04-09 | 2004-04-06 | Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor |
Country Status (32)
Country | Link |
---|---|
US (4) | US20040202658A1 (en) |
EP (2) | EP1613350B1 (en) |
JP (3) | JP2006522811A (en) |
KR (2) | KR101092171B1 (en) |
CN (2) | CN1802176A (en) |
AT (1) | ATE425766T1 (en) |
AU (1) | AU2004229376B2 (en) |
BR (1) | BRPI0409534A (en) |
CA (1) | CA2519870A1 (en) |
CR (1) | CR8033A (en) |
CY (1) | CY1109127T1 (en) |
DE (1) | DE602004020061D1 (en) |
DK (1) | DK1613350T3 (en) |
EC (1) | ECSP056082A (en) |
ES (1) | ES2322267T3 (en) |
HK (1) | HK1086480A1 (en) |
HR (2) | HRP20050940A2 (en) |
IL (2) | IL171038A (en) |
MA (1) | MA27838A1 (en) |
ME (1) | ME00426B (en) |
MX (1) | MXPA05010778A (en) |
NO (1) | NO20055253L (en) |
NZ (2) | NZ587776A (en) |
PL (1) | PL1613350T3 (en) |
PT (1) | PT1613350E (en) |
RS (1) | RS51686B (en) |
RU (1) | RU2358762C9 (en) |
SI (1) | SI1613350T1 (en) |
TN (1) | TNSN05234A1 (en) |
UA (2) | UA99933C2 (en) |
WO (1) | WO2004091657A2 (en) |
ZA (1) | ZA200507805B (en) |
Families Citing this family (108)
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ATE311199T1 (en) | 1999-05-07 | 2005-12-15 | Genentech Inc | TREATMENT OF AUTOIMMUNE DISEASES WITH ANTAGONISTS THAT BIND SURFACE MARKERS OF B CELLS |
HUP0202238A3 (en) * | 1999-07-12 | 2004-05-28 | Idec Pharmaceuticals Inc San D | Blocking immune response to a foreign antigen using an antagonist which binds to cd20 |
DE60334364D1 (en) | 2002-02-21 | 2010-11-11 | Univ California | TREATMENT PROCEDURE USING ANTI-CD22 ANTIBODIES |
US20090217404A1 (en) * | 2002-09-27 | 2009-08-27 | Lowe Scott W | Cell-based RNA interference and related methods and compositions |
ES2633311T3 (en) * | 2002-12-16 | 2017-09-20 | Genentech, Inc. | Immunoglobulin variants and uses thereof |
WO2004074445A2 (en) * | 2003-02-17 | 2004-09-02 | Cold Spring Harbor Laboratory | Model for studying the role of genes in tumor resistance to chemotherapy |
US20090186839A1 (en) * | 2003-02-17 | 2009-07-23 | Cold Spring Harbor Laboratory | Model for studying the role of genes in chemoresistance |
EP1460088A1 (en) * | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
JP2006522811A (en) | 2003-04-09 | 2006-10-05 | ジェネンテック・インコーポレーテッド | Method for treating autoimmune disease in patients with inadequate response to TNFα inhibitors |
JP5416338B2 (en) * | 2003-05-09 | 2014-02-12 | デューク ユニバーシティ | CD20-specific antibody and method of use thereof |
AR044388A1 (en) * | 2003-05-20 | 2005-09-07 | Applied Molecular Evolution | CD20 UNION MOLECULES |
MXPA06002134A (en) * | 2003-08-29 | 2006-05-31 | Genentech Inc | Anti-cd20 therapy of ocular disorders. |
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MXPA06014067A (en) * | 2004-06-04 | 2007-02-15 | Genentech Inc | Method for treating lupus. |
AU2005267028A1 (en) * | 2004-07-22 | 2006-02-02 | Genentech, Inc. | Method of treating Sjogren's syndrome |
JP5055603B2 (en) | 2004-08-04 | 2012-10-24 | メントリック・バイオテック・リミテッド・ライアビリティ・カンパニー | Mutated Fc region |
RU2411956C2 (en) * | 2004-10-05 | 2011-02-20 | Дженентек, Инк. | Method of treating vasculitis |
US8137907B2 (en) * | 2005-01-03 | 2012-03-20 | Cold Spring Harbor Laboratory | Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof |
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US20060263357A1 (en) * | 2005-05-05 | 2006-11-23 | Tedder Thomas F | Anti-CD19 antibody therapy for autoimmune disease |
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- 2004-04-06 CN CNA2004800161012A patent/CN1802176A/en active Pending
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2005
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2006
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2008
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2009
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2011
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