RS51686B - Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor - Google Patents

Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor

Info

Publication number
RS51686B
RS51686B YU20050761A YUP76105A RS51686B RS 51686 B RS51686 B RS 51686B YU 20050761 A YU20050761 A YU 20050761A YU P76105 A YUP76105 A YU P76105A RS 51686 B RS51686 B RS 51686B
Authority
RS
Serbia
Prior art keywords
tnf
therapy
patient
inadequate response
autoimmune disease
Prior art date
Application number
YU20050761A
Other languages
Serbian (sr)
Inventor
Mark Benyunes
Original Assignee
Genentech Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33299824&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS51686(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc. filed Critical Genentech Inc.
Publication of RS20050761A publication Critical patent/RS20050761A/en
Publication of RS51686B publication Critical patent/RS51686B/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
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    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • AIDS & HIV (AREA)
  • Biomedical Technology (AREA)

Abstract

Upotreba antitela u proizvodnji leka za lečenje reumatoidnog artritisa davanjem dve doze antitela od 1000 mg čoveku koji ima neadekvatni odgovor na inhibitor TNFa, gde je prva doza davana 1. dana lečenja, a druga doza 15. dana, gde je antitelo rituksimab, i gde je inhibitor TNFa etanercept, infliksimab i adalimumab.Prijava sadrži još 4 patentna zahteva.Use of antibodies in the manufacture of a medicament for the treatment of rheumatoid arthritis by administering two doses of 1000 mg of antibody to a human having an inadequate response to a TNFα inhibitor, where the first dose is given on day 1 of treatment and the second dose on day 15, where the antibody is rituximab TNFα inhibitor etanercept, infliximab and adalimumab. The application contains 4 more claims.

YU20050761A 2003-04-09 2004-04-06 Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor RS51686B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46148103P 2003-04-09 2003-04-09
PCT/US2004/010509 WO2004091657A2 (en) 2003-04-09 2004-04-06 Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor

Publications (2)

Publication Number Publication Date
RS20050761A RS20050761A (en) 2007-11-15
RS51686B true RS51686B (en) 2011-10-31

Family

ID=33299824

Family Applications (1)

Application Number Title Priority Date Filing Date
YU20050761A RS51686B (en) 2003-04-09 2004-04-06 Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor

Country Status (32)

Country Link
US (4) US20040202658A1 (en)
EP (2) EP1613350B1 (en)
JP (3) JP2006522811A (en)
KR (2) KR101092171B1 (en)
CN (2) CN1802176A (en)
AT (1) ATE425766T1 (en)
AU (1) AU2004229376B2 (en)
BR (1) BRPI0409534A (en)
CA (1) CA2519870A1 (en)
CR (1) CR8033A (en)
CY (1) CY1109127T1 (en)
DE (1) DE602004020061D1 (en)
DK (1) DK1613350T3 (en)
EC (1) ECSP056082A (en)
ES (1) ES2322267T3 (en)
HK (1) HK1086480A1 (en)
HR (2) HRP20050940A2 (en)
IL (2) IL171038A (en)
MA (1) MA27838A1 (en)
ME (1) ME00426B (en)
MX (1) MXPA05010778A (en)
NO (1) NO20055253L (en)
NZ (2) NZ587776A (en)
PL (1) PL1613350T3 (en)
PT (1) PT1613350E (en)
RS (1) RS51686B (en)
RU (1) RU2358762C9 (en)
SI (1) SI1613350T1 (en)
TN (1) TNSN05234A1 (en)
UA (2) UA99933C2 (en)
WO (1) WO2004091657A2 (en)
ZA (1) ZA200507805B (en)

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