RS49561B - Process for enzymatic synthesis of triazol-nucleosides by use of thermophilic bacteria - Google Patents

Process for enzymatic synthesis of triazol-nucleosides by use of thermophilic bacteria

Info

Publication number
RS49561B
RS49561B YUP-775/93A YU77593A RS49561B RS 49561 B RS49561 B RS 49561B YU 77593 A YU77593 A YU 77593A RS 49561 B RS49561 B RS 49561B
Authority
RS
Serbia
Prior art keywords
thermophilic bacteria
nucleosides
enzymatic synthesis
triazol
triazolo
Prior art date
Application number
YUP-775/93A
Other languages
Serbian (sr)
Inventor
Gordana Opačić
Ljubinka Gligić
Željka Radulović
Valentina Živković
Lola Matić
Smith Robert
Original Assignee
Galenika A.D.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galenika A.D., filed Critical Galenika A.D.,
Priority to YUP-775/93A priority Critical patent/RS49561B/en
Priority to PCT/CA1994/000261 priority patent/WO1995016785A1/en
Priority to AU67182/94A priority patent/AU6718294A/en
Priority to CN 94190019 priority patent/CN1111061A/en
Publication of YU77593A publication Critical patent/YU77593A/en
Publication of RS49561B publication Critical patent/RS49561B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Postupak za enzimsku sintezu triazolo neukleozida primenom termofilnih bakterija izolovanih iz geotermalnih izvora, naznačen time, što se reakcijom triazolo derivata sa donorima riboze, u prisustvu biomase termofilnih bakterija Thermothrix ihiopara kao izvora enzima, uz dodatak neorganskih fosfata kao katalizatora i sredstva za fosforilaciju riboze, dobijaju farmaceutski aktivna jedinjenja kod kojih je ribozo grupa vezana za triazol. Prijava sadrži još 1 nezavisan i 7 zavisnih patentnih zahteva. <patent>Process for the enzymatic synthesis of triazolo nucleosides using thermophilic bacteria isolated from geothermal sources, characterized in that the reaction of triazolo derivatives with ribose donors in the presence of thermophilic bacteria Thermothrix ihiopara as an enzyme source, with the addition of inorganic phosphates as catalysts and phosphorylation agents, pharmaceutically active compounds wherein the ribose group is bound to triazole. The application contains 1 more independent and 7 dependent patent claims. <patent>

YUP-775/93A 1993-12-14 1993-12-14 Process for enzymatic synthesis of triazol-nucleosides by use of thermophilic bacteria RS49561B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
YUP-775/93A RS49561B (en) 1993-12-14 1993-12-14 Process for enzymatic synthesis of triazol-nucleosides by use of thermophilic bacteria
PCT/CA1994/000261 WO1995016785A1 (en) 1993-12-14 1994-05-12 Use of thermophilic bacteria to manufacture triazole nucleosides
AU67182/94A AU6718294A (en) 1993-12-14 1994-05-12 Use of thermophilic bacteria to manufacture triazole nucleosides
CN 94190019 CN1111061A (en) 1993-12-14 1994-05-12 Use of thrmophilic bacteria to manufacture triazole nucleosides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YUP-775/93A RS49561B (en) 1993-12-14 1993-12-14 Process for enzymatic synthesis of triazol-nucleosides by use of thermophilic bacteria

Publications (2)

Publication Number Publication Date
YU77593A YU77593A (en) 1997-03-07
RS49561B true RS49561B (en) 2007-04-10

Family

ID=25551391

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-775/93A RS49561B (en) 1993-12-14 1993-12-14 Process for enzymatic synthesis of triazol-nucleosides by use of thermophilic bacteria

Country Status (4)

Country Link
CN (1) CN1111061A (en)
AU (1) AU6718294A (en)
RS (1) RS49561B (en)
WO (1) WO1995016785A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2338985A1 (en) 2009-12-22 2011-06-29 Institut Univ. de Ciència i Tecnologia, s.a. Thermostable biocatalyst combination for nucleoside synthesis
RU2480218C1 (en) * 2011-12-06 2013-04-27 Российская Федерация, От Имени Которой Выступает Министерство Промышленности И Торговли Российской Федерации METHOD OF PRODUCING 1-β-D-RIBOFURANOSYL-1,2,4-TRIAZOLE-3-CARBOXAMIDE
CN112980906B (en) * 2021-04-14 2021-07-30 深圳瑞德林生物技术有限公司 Enzyme composition for preparing beta-nicotinamide mononucleotide and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614719A (en) * 1982-04-30 1986-09-30 Yamasa Shoyu Kabushiki Kaisha Process for producing ribavirin
US4840898A (en) * 1987-09-17 1989-06-20 Eastman Kodak Company High temperature method for the production of ribavirin
DE69027154T2 (en) * 1989-02-28 1996-10-24 Yamasa Shoyu K.K. (Yamasa Corp.), Chosi, Chiba Process for the preparation of nucleosides by using phosphorylases obtainable from Bacillus stearothermophilus

Also Published As

Publication number Publication date
CN1111061A (en) 1995-11-01
AU6718294A (en) 1995-07-03
YU77593A (en) 1997-03-07
WO1995016785A1 (en) 1995-06-22

Similar Documents

Publication Publication Date Title
HN1999000083A (en) PIRROLO COMPOUNDS (2,3-D) PYRIMIDINE
AU9536898A (en) 4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the holesterin-ester transfer protein
ZA981936B (en) Novel benzimidazole inhibitors of fructose 1,6-bisphosphatase.
BR0111561A (en) Pyrrolo [2,3-d] pyrimidine compound as immunosuppressive agents
DK1052984T3 (en) Antibacterial agents
DK177585A (en) pyridazinones
ES2165368T3 (en) CULTURE OF ANIMAL CELLS.
MY137020A (en) Diazabicyclic central nervous system active agents
YU19499A (en) Benzonaphthyridines as bronchial therapeutics
MY129998A (en) Saccharin derivative proteolytic enzyme inhibitors
ES2151608T3 (en) NEW ANTIBIOTIC COMPOUNDS AND ANTIBIOTIC COMPOSITIONS THAT INCLUDE SUCH COMPOUNDS TO INHIBIT POSITIVE GRAM BACTERIA CELLS AND MICOPLASMS.
AU7548500A (en) Compositions and methods for inhibiting g2 cell cycle arrest and sensitizing cells to dna damaging agents
ES2091322T3 (en) COMPOUNDS OF GUANINE, GUANOSINE AND 2&#39;-DEOXYGUANOSINE BENCILLATED IN O6 THAT POSSESS ACTIVITY OF EMOODING IN O6-ALKYLGUANINE-DNA-ALKYL TRANSFERASE.
RS49561B (en) Process for enzymatic synthesis of triazol-nucleosides by use of thermophilic bacteria
Potvin et al. Inhibition by barbituric acid and its derivatives of the enzymes in rat brain which participate in the synthesis of pyrimidine ribotides
DE69625910D1 (en) PENAMSULPHONES AS BETA LACTAMASE INHIBITORS
Sun et al. The effect of substrate availability on the metabolism of arachidonic acid in human platelets
ES2193207T3 (en) PROCEDURE FOR THE FEMENTATIVE PREPARATION OF CLAVAMA DERIVATIVES IN WHICH THE LEVELS OF AMMONIA AND UREA ARE MAINTAINED IN THE MIDDLE OF FERMENTATION.
Nakatani et al. Germinability of coat-lacking spores of Bacillusmegaterium
Shirae et al. Adenosine phosphorolyzing enzymes from microorganisms and ribavirin production by the application of the enzyme
AU1402495A (en) Use of macrophage depleting agents for prolonging the survival of non-autologus hematopoietic cell transplants and animal model assay systems
EA199900508A1 (en) AGRICULTURAL COMPOSITIONS CONTAINING BACTERIA
ES2194207T3 (en) NEW USEFUL TRICICLIC N-CYANOIMINES AS INHIBITORS OF THE FARNESIL-PROTEIN-TRANSFERASA.
Cramp The effect of methoirexate on dihydrofolic reductase in the rat liver
GB9723905D0 (en) Heterocyclic compounds having MMP and TNF inhibitory activity