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Application filed by Aurora Moldovan, Maria Taizs, Vasile NeagufiledCriticalAurora Moldovan
Priority to RO124467ApriorityCriticalpatent/RO96198B1/en
Publication of RO96198A2publicationCriticalpatent/RO96198A2/en
Publication of RO96198B1publicationCriticalpatent/RO96198B1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Inventia se refera la un procedeu de obtinere a unui medicament cu actiune anticanceroasa, în care acidul retinoic este supus granularii umede cu polivinilpirolidona, separat se granuleaza un amestec de substante inerte uzual, în acelasi mod, raportul între substanta activa: amestec inactiv fiind de 1:8...10, granulatele astfel obtinute se amesteca, se comprima pentru obtinerea unor nuclee care, la rândul lor, se izoleaza cu solutie de polivinilpirolidona în alcool izopropilic se usuca si se supune drajefierii într-un mod cunoscut.The invention relates to a process for obtaining an anti-cancer drug, wherein the retinoic acid is subjected to wet granulation with polyvinylpyrrolidone, a mixture of normally inert substances is granulated in the same way, the ratio of the active substance: the inactive mixture is 1 : 8 ... 10, the granules thus obtained are mixed, compressed to obtain nuclei which in turn are isolated with a solution of polyvinylpyrrolidone in isopropyl alcohol is dried and subjected to drageing in a known manner.
RO124467A1986-08-081986-08-08Process for preparing a medicine having anticancerous activity
RO96198B1
(en)
Process for the production of new tiophenecarbonic acid esthers of amino-alcoholes, their quaterner derivatives and of medical preparations containing them as active agents
Process for production of insecticides and acaricides containing pirasoline-derivatives as active substance and process for production of the active substances