RO91672B1 - Procedeu de obtinere a 10,11-dihidro-n,n-dimrtil-5h-dibenzo-(a, d)- ciclohepten-5-propilaminei - Google Patents
Procedeu de obtinere a 10,11-dihidro-n,n-dimrtil-5h-dibenzo-(a, d)- ciclohepten-5-propilamineiInfo
- Publication number
- RO91672B1 RO91672B1 RO118117A RO11811785A RO91672B1 RO 91672 B1 RO91672 B1 RO 91672B1 RO 118117 A RO118117 A RO 118117A RO 11811785 A RO11811785 A RO 11811785A RO 91672 B1 RO91672 B1 RO 91672B1
- Authority
- RO
- Romania
- Prior art keywords
- dibenzo
- cyclohepten
- propylamine
- dihydro
- dimethyl
- Prior art date
Links
- 238000003747 Grignard reaction Methods 0.000 abstract 1
- 229960000836 amitriptyline Drugs 0.000 abstract 1
- KRMDCWKBEZIMAB-UHFFFAOYSA-N amitriptyline Chemical compound C1CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 KRMDCWKBEZIMAB-UHFFFAOYSA-N 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Inventia se refera la obtinerea 10,11-dihidro-N,N-dimetil-5H-dibenzo-(a,b)-cicloheptan-5-hidroxi-5-propilaminei, intermediar în sinteza unor medicamente antidepresive ca amitriptilina simortriptilina, printr-o reactie Grignard dintre 10,11-dihiro-5-H-dibenzo-(a,d)-ciclohepten-5-ona si 1,3-dimetilamiclorpropan într-o singura etapa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO118117A RO91672B1 (ro) | 1985-03-25 | 1985-03-25 | Procedeu de obtinere a 10,11-dihidro-n,n-dimrtil-5h-dibenzo-(a, d)- ciclohepten-5-propilaminei |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO118117A RO91672B1 (ro) | 1985-03-25 | 1985-03-25 | Procedeu de obtinere a 10,11-dihidro-n,n-dimrtil-5h-dibenzo-(a, d)- ciclohepten-5-propilaminei |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO91672A2 RO91672A2 (ro) | 1987-07-30 |
| RO91672B1 true RO91672B1 (ro) | 1987-07-31 |
Family
ID=20116834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO118117A RO91672B1 (ro) | 1985-03-25 | 1985-03-25 | Procedeu de obtinere a 10,11-dihidro-n,n-dimrtil-5h-dibenzo-(a, d)- ciclohepten-5-propilaminei |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO91672B1 (ro) |
-
1985
- 1985-03-25 RO RO118117A patent/RO91672B1/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO91672A2 (ro) | 1987-07-30 |
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