RO87964B1 - Acridine derivative and process for obtaining the same - Google Patents
Acridine derivative and process for obtaining the sameInfo
- Publication number
- RO87964B1 RO87964B1 RO113559A RO11355982A RO87964B1 RO 87964 B1 RO87964 B1 RO 87964B1 RO 113559 A RO113559 A RO 113559A RO 11355982 A RO11355982 A RO 11355982A RO 87964 B1 RO87964 B1 RO 87964B1
- Authority
- RO
- Romania
- Prior art keywords
- acridine derivative
- obtaining
- same
- formula
- dichloroacetyltetradecahydroacridine
- Prior art date
Links
- 125000000641 acridinyl group Chemical class C1(=CC=CC2=NC3=CC=CC=C3C=C12)* 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- RXBYRTSOWREATF-UHFFFAOYSA-N 1,2,3,4-tetrahydroacridine Chemical compound C1=CC=C2C=C(CCCC3)C3=NC2=C1 RXBYRTSOWREATF-UHFFFAOYSA-N 0.000 abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- MVPPADPHJFYWMZ-UHFFFAOYSA-N chlorobenzene Chemical compound ClC1=CC=CC=C1 MVPPADPHJFYWMZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- -1 N-dichloroacetyltetradecahydroacridine Chemical compound 0.000 abstract 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 abstract 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 abstract 1
- 150000008041 alkali metal carbonates Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- FBCCMZVIWNDFMO-UHFFFAOYSA-N dichloroacetyl chloride Chemical compound ClC(Cl)C(Cl)=O FBCCMZVIWNDFMO-UHFFFAOYSA-N 0.000 abstract 1
- 150000004679 hydroxides Chemical class 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 125000005270 trialkylamine group Chemical group 0.000 abstract 1
- 239000008096 xylene Substances 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
Inventia se refera la un derivat de acridina care este N-dicloracetil-tetradecahidroacridina cu structura chimica corespunzatoare formulei I: (vezi formula) si este o substanta cristalina alba, cu punct de topire de 175-176 degree C si la procedeul de obtinere a acestuia care consta în aceea ca tetrahidroacridina se trateaza la temperatura camerei cu clorura de dicloracetil în raport molar de 1:1, în prezenta unui solvent organic inert ales dintre eter etilic, benzen, toluen, xilen, hexan, heptan, diclormetan, cloroform, tetraclorura de carbon, clorbenzen si acetona si a unui acceptor de acid clorhidric ales dintre trialchil-amine, piridina, hidroxizi si carbonati de metale alcaline.The invention relates to an acridine derivative which is N-dichloroacetyltetradecahydroacridine of the chemical structure of the formula I: (see formula) and is a white crystalline substance with a melting point of 175-176 ° C and the process for its preparation which consists in treating the tetrahydroacridine at room temperature with dichloroacetyl chloride in a molar ratio of 1: 1 in the presence of an inert organic solvent selected from ethyl ether, benzene, toluene, xylene, hexane, heptane, dichloromethane, chloroform, carbon, chlorobenzene and acetone and a hydrochloric acid acceptor selected from trialkylamines, pyridine, hydroxides and alkali metal carbonates.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO82113559A RO87964A2 (en) | 1982-01-21 | 1982-01-21 | ACRIDINE DERIVATIVE AND METHOD OF OBTAINING |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO82113559A RO87964A2 (en) | 1982-01-21 | 1982-01-21 | ACRIDINE DERIVATIVE AND METHOD OF OBTAINING |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO87964B1 true RO87964B1 (en) | 1985-10-31 |
| RO87964A2 RO87964A2 (en) | 1985-11-30 |
Family
ID=20114386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO82113559A RO87964A2 (en) | 1982-01-21 | 1982-01-21 | ACRIDINE DERIVATIVE AND METHOD OF OBTAINING |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO87964A2 (en) |
-
1982
- 1982-01-21 RO RO82113559A patent/RO87964A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO87964A2 (en) | 1985-11-30 |
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