RO87312B1 - PROCEDEU DE OBtINERE A HIALURONIDAZEI - Google Patents
PROCEDEU DE OBtINERE A HIALURONIDAZEIInfo
- Publication number
- RO87312B1 RO87312B1 RO112094A RO11209483A RO87312B1 RO 87312 B1 RO87312 B1 RO 87312B1 RO 112094 A RO112094 A RO 112094A RO 11209483 A RO11209483 A RO 11209483A RO 87312 B1 RO87312 B1 RO 87312B1
- Authority
- RO
- Romania
- Prior art keywords
- hyluronidase
- preparing
- viscines
- sprats
- anchovies
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000251468 Actinopterygii Species 0.000 abstract 1
- 241000555825 Clupeidae Species 0.000 abstract 1
- 241001454694 Clupeiformes Species 0.000 abstract 1
- 108010003272 Hyaluronate lyase Proteins 0.000 abstract 1
- 102000001974 Hyaluronidases Human genes 0.000 abstract 1
- 239000008351 acetate buffer Substances 0.000 abstract 1
- YBCVMFKXIKNREZ-UHFFFAOYSA-N acoh acetic acid Chemical compound CC(O)=O.CC(O)=O YBCVMFKXIKNREZ-UHFFFAOYSA-N 0.000 abstract 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 abstract 1
- 235000011130 ammonium sulphate Nutrition 0.000 abstract 1
- 235000019513 anchovy Nutrition 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 235000019688 fish Nutrition 0.000 abstract 1
- 229960002773 hyaluronidase Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Procedeul de obtinere a hialuronidazei, conform inventiei, consta în aceea ca viscerele bine omogenizate de la pestele marunt ales dintre hamsie si sprot se extrag, în doua faze, succesive, cu solutie tampon acid acetic-acetat cu pH 4,3 dupa care extractelor reunite li se adauga sulfat de amoniu se lasa în repaus o ora, dupa,care se filtreaza si precipitatul obtinut se purifica prin dializare în curent continuu fata de apa distilata, produsul obtinut conservandu-se prin liofilizare.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO112094A RO87312B1 (ro) | 1983-09-19 | 1983-09-19 | PROCEDEU DE OBtINERE A HIALURONIDAZEI |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO112094A RO87312B1 (ro) | 1983-09-19 | 1983-09-19 | PROCEDEU DE OBtINERE A HIALURONIDAZEI |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RO87312B1 true RO87312B1 (ro) | 1985-07-31 |
Family
ID=40903913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO112094A RO87312B1 (ro) | 1983-09-19 | 1983-09-19 | PROCEDEU DE OBtINERE A HIALURONIDAZEI |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO87312B1 (ro) |
-
1983
- 1983-09-19 RO RO112094A patent/RO87312B1/ro unknown
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