RO82040B1 - N-substituted bislactams and process for obtaining the same - Google Patents

N-substituted bislactams and process for obtaining the same

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Publication number
RO82040B1
RO82040B1 RO101363A RO10136380A RO82040B1 RO 82040 B1 RO82040 B1 RO 82040B1 RO 101363 A RO101363 A RO 101363A RO 10136380 A RO10136380 A RO 10136380A RO 82040 B1 RO82040 B1 RO 82040B1
Authority
RO
Romania
Prior art keywords
bislactams
substituted
obtaining
same
general formula
Prior art date
Application number
RO101363A
Other languages
Romanian (ro)
Other versions
RO82040A2 (en
Inventor
Dumitru Dobrescu
Mircea Iovu
Aurelia-Nicoleta Cristea
Mohamed Abd El Hafez Omaima
Original Assignee
Dumitru Dobrescu
Mircea Iovu
Aurelia-Nicoleta Cristea
Mohamed Abd El Hafez Omaima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dumitru Dobrescu, Mircea Iovu, Aurelia-Nicoleta Cristea, Mohamed Abd El Hafez Omaima filed Critical Dumitru Dobrescu
Priority to RO80101363A priority Critical patent/RO82040A2/en
Publication of RO82040B1 publication Critical patent/RO82040B1/en
Publication of RO82040A2 publication Critical patent/RO82040A2/en

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Abstract

Inventia se refera la o bislactame-N-substituite cu actiune analgezica care, au formula generala: (vezi formula) în care m are valoarea cuprinsa între 3 si 5, iar n între 0 si 4, acestea fiind substante solide, cristaline cu puncte de topire cuprinse între 147 si 221 degree C. Produsul de preparare a bislactamelor cu formula generala de mai sus, consta în aceea ca se trateaza lactamatii alcalini cu biclormetil derivati aromatici reactia avînd loc în prezenta unui sovent ales dintre: benzen, toluen sau xileni, etanol, la temperaturi cuprinse între temperatura camerei si teperatura de fierbere a solventului.The invention relates to a N-substituted bis-lactam-analgesic action having the general formula: wherein m is between 3 and 5, and n is between 0 and 4, being solid, crystalline, melting range between 147 DEG and 221 DEG C. The product of preparation of the bislactams of the general formula above consists in treating the alkali lactamases with a dichloromethyl aromatic derivative reaction in the presence of a solvent selected from benzene, , at temperatures between room temperature and the boiling temperature of the solvent.

RO80101363A 1980-06-09 1980-06-09 N-SUBSTITUTED BISLACTAMES AND PROCESS FOR OBTAINING RO82040A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RO80101363A RO82040A2 (en) 1980-06-09 1980-06-09 N-SUBSTITUTED BISLACTAMES AND PROCESS FOR OBTAINING

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RO80101363A RO82040A2 (en) 1980-06-09 1980-06-09 N-SUBSTITUTED BISLACTAMES AND PROCESS FOR OBTAINING

Publications (2)

Publication Number Publication Date
RO82040B1 true RO82040B1 (en) 1983-06-30
RO82040A2 RO82040A2 (en) 1983-07-07

Family

ID=20108632

Family Applications (1)

Application Number Title Priority Date Filing Date
RO80101363A RO82040A2 (en) 1980-06-09 1980-06-09 N-SUBSTITUTED BISLACTAMES AND PROCESS FOR OBTAINING

Country Status (1)

Country Link
RO (1) RO82040A2 (en)

Also Published As

Publication number Publication date
RO82040A2 (en) 1983-07-07

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