RO73044B1 - Saruri ale acidului 1-(4-clorbenzoil)-5-metoxi-2-metil-1h-indol-3-acetic cu metale bivalente si procedeu de obtinere a acestora - Google Patents
Saruri ale acidului 1-(4-clorbenzoil)-5-metoxi-2-metil-1h-indol-3-acetic cu metale bivalente si procedeu de obtinere a acestoraInfo
- Publication number
- RO73044B1 RO73044B1 RO92563A RO9256377A RO73044B1 RO 73044 B1 RO73044 B1 RO 73044B1 RO 92563 A RO92563 A RO 92563A RO 9256377 A RO9256377 A RO 9256377A RO 73044 B1 RO73044 B1 RO 73044B1
- Authority
- RO
- Romania
- Prior art keywords
- methoxy
- methyl
- acetic acid
- chlorobenzoyl
- salts
- Prior art date
Links
- 229910052751 metal Inorganic materials 0.000 title abstract 4
- 239000002184 metal Substances 0.000 title abstract 4
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical class CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 150000002739 metals Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 abstract 2
- 229910017052 cobalt Inorganic materials 0.000 abstract 2
- 239000010941 cobalt Substances 0.000 abstract 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 abstract 1
- 235000019341 magnesium sulphate Nutrition 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 229960002523 mercuric chloride Drugs 0.000 abstract 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 abstract 1
- 229910052753 mercury Inorganic materials 0.000 abstract 1
- LWJROJCJINYWOX-UHFFFAOYSA-L mercury dichloride Chemical compound Cl[Hg]Cl LWJROJCJINYWOX-UHFFFAOYSA-L 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Landscapes
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Saruri ale acidului 1-(4-clor-benzoil)-5-metoxi-2-metil-1H-indol-3-acetic cu metale bivalente, caracterizate prin aceea ca au structura chimica conform formulei generale I: (vezi formula) în care Me reprezinta un metal bivalent ales dintre magneziu,mercur si cobalt, si sînt substante solide, cu puncte de topire de la 149 la 152 degree C. Procedeul de obtinere a unor saruri conform revendicarii 1, caracterizat prin aceea ca se trateaza o solutie alcoolica de acid 1-(4-clorbenzoil)-5-metoxi-2-metil-1H-i ndol-3-acetic cu o solutie apoasa sau hidroalcoolica a unei sari de metal bivalent, aleasa dintre sulfatul de magneziu, clorura mercurica si clorura de cobalt într-un raport molar de 1:2, la temepratura camerei.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO7792563A RO73044A2 (ro) | 1977-12-21 | 1977-12-21 | Saruri ale acidului 1-(4-clorbenzoil)-5-metoxi-2-metil-1h-indol-3-acetic cu metale bivalente si procedeu de obtinere a acestora |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO7792563A RO73044A2 (ro) | 1977-12-21 | 1977-12-21 | Saruri ale acidului 1-(4-clorbenzoil)-5-metoxi-2-metil-1h-indol-3-acetic cu metale bivalente si procedeu de obtinere a acestora |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO73044B1 true RO73044B1 (ro) | 1983-05-30 |
| RO73044A2 RO73044A2 (ro) | 1983-06-01 |
Family
ID=20099127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO7792563A RO73044A2 (ro) | 1977-12-21 | 1977-12-21 | Saruri ale acidului 1-(4-clorbenzoil)-5-metoxi-2-metil-1h-indol-3-acetic cu metale bivalente si procedeu de obtinere a acestora |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO73044A2 (ro) |
-
1977
- 1977-12-21 RO RO7792563A patent/RO73044A2/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO73044A2 (ro) | 1983-06-01 |
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