RO72884B - Process for preparing indolic compounds - Google Patents
Process for preparing indolic compoundsInfo
- Publication number
- RO72884B RO72884B RO81868A RO8186875A RO72884B RO 72884 B RO72884 B RO 72884B RO 81868 A RO81868 A RO 81868A RO 8186875 A RO8186875 A RO 8186875A RO 72884 B RO72884 B RO 72884B
- Authority
- RO
- Romania
- Prior art keywords
- preparing
- indolic compounds
- compounds
- chloro
- methyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Inventia se refera la un procedeu pentru prepararea de compusi indolici cu formula I din pag.1 a descrierii, în care X reprezinta clor, fluor, brom, metil, Z reprezinta fluor, clor, metoxi, R reprezinta o grupa în care A reprezinta -(CH2) indice m- în care m este 1 sau 2, Y reprezinta hidrogen, clor, fluor, metil, constînd în aceea ca se aduce în reactie un derivat indolic cu formula II în care Z, X si m au semnificatia aratata mai sus.The invention relates to a process for the preparation of the indole compounds of formula I of the description, wherein X represents chlorine, fluorine, bromine, methyl, Z represents fluoro, chloro, methoxy, R represents a group wherein A represents - (CH2) m - wherein m is 1 or 2, Y is hydrogen, chloro, fluoro, methyl, in that an indole derivative of the formula II in which Z, X and m are as defined above .
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45664074A | 1974-04-01 | 1974-04-01 | |
| US456641A US3925409A (en) | 1974-04-01 | 1974-04-01 | 4-Aryl-1,2,3,4-tetrahydropyrrolo{8 3,4-b{9 indoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO72884B true RO72884B (en) | 1983-07-30 |
| RO72884A RO72884A (en) | 1983-08-03 |
Family
ID=27038317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO7581868A RO72884A (en) | 1974-04-01 | 1975-04-01 | PROCESS FOR THE PREPARATION OF INDOLIC COMPOUNDS |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS587635B2 (en) |
| AR (2) | AR207799A1 (en) |
| AU (1) | AU7955975A (en) |
| DD (1) | DD118879A5 (en) |
| DE (1) | DE2514084A1 (en) |
| DK (2) | DK130575A (en) |
| ES (3) | ES436157A1 (en) |
| FI (1) | FI750940A (en) |
| FR (1) | FR2265368A1 (en) |
| IL (1) | IL46925A0 (en) |
| LU (1) | LU72182A1 (en) |
| NL (1) | NL7503700A (en) |
| NO (1) | NO751055L (en) |
| RO (1) | RO72884A (en) |
| SE (2) | SE423630B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224329A (en) * | 1979-01-23 | 1980-09-23 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| US4451655A (en) * | 1982-05-17 | 1984-05-29 | Pfizer Inc. | Process for preparing carboline derivatives and compounds used in their preparation |
| AU765751B2 (en) * | 1998-12-21 | 2003-09-25 | Janssen Pharmaceutica N.V. | Benzisoxazoles and phenones as alpha2-antagonists |
| RU2320662C1 (en) * | 2006-08-24 | 2008-03-27 | Андрей Александрович Иващенко | SUBSTITUTED PYRROLO[4,3-b]INDOLES, COMBINATORY AND FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION, METHODS FOR THEIR PREPARING AND USING |
| US8993572B2 (en) * | 2010-04-22 | 2015-03-31 | Intra-Cellular Therapies, Inc. | Pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines derivatives and [1,4]oxazino[2,3,4-hi]pyrido[4,3-b]indole derivatives |
-
1975
- 1975-01-01 AR AR261449A patent/AR207799A1/en active
- 1975-01-01 AR AR258188A patent/AR206812A1/en active
- 1975-03-14 SE SE7502927A patent/SE423630B/en unknown
- 1975-03-25 IL IL46925A patent/IL46925A0/en unknown
- 1975-03-25 NO NO751055A patent/NO751055L/no unknown
- 1975-03-26 AU AU79559/75A patent/AU7955975A/en not_active Expired
- 1975-03-26 DK DK130575A patent/DK130575A/da not_active Application Discontinuation
- 1975-03-27 NL NL7503700A patent/NL7503700A/en not_active Application Discontinuation
- 1975-03-27 FI FI750940A patent/FI750940A/fi not_active Application Discontinuation
- 1975-03-29 DE DE19752514084 patent/DE2514084A1/en not_active Ceased
- 1975-03-31 ES ES436157A patent/ES436157A1/en not_active Expired
- 1975-04-01 RO RO7581868A patent/RO72884A/en unknown
- 1975-04-01 LU LU72182A patent/LU72182A1/xx unknown
- 1975-04-01 JP JP50040224A patent/JPS587635B2/en not_active Expired
- 1975-04-01 DD DD185114A patent/DD118879A5/xx unknown
- 1975-04-01 FR FR7510139A patent/FR2265368A1/en active Granted
-
1976
- 1976-11-30 ES ES453788A patent/ES453788A1/en not_active Expired
- 1976-11-30 ES ES453787A patent/ES453787A1/en not_active Expired
-
1978
- 1978-05-01 DK DK187878A patent/DK187878A/en not_active Application Discontinuation
-
1982
- 1982-01-07 SE SE8200047A patent/SE8200047L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SE7502927L (en) | 1975-10-02 |
| NO751055L (en) | 1975-10-02 |
| SE8200047L (en) | 1982-01-07 |
| AR207799A1 (en) | 1976-10-29 |
| NL7503700A (en) | 1975-10-03 |
| ES436157A1 (en) | 1977-04-16 |
| AR206812A1 (en) | 1976-08-23 |
| ES453787A1 (en) | 1978-01-01 |
| LU72182A1 (en) | 1976-03-02 |
| JPS587635B2 (en) | 1983-02-10 |
| RO72884A (en) | 1983-08-03 |
| FR2265368A1 (en) | 1975-10-24 |
| FI750940A (en) | 1975-10-02 |
| IL46925A0 (en) | 1975-05-22 |
| SE423630B (en) | 1982-05-17 |
| FR2265368B1 (en) | 1978-07-28 |
| DD118879A5 (en) | 1976-03-20 |
| ES453788A1 (en) | 1978-01-01 |
| DK130575A (en) | 1975-10-02 |
| DE2514084A1 (en) | 1975-11-20 |
| JPS50140494A (en) | 1975-11-11 |
| DK187878A (en) | 1978-05-01 |
| AU7955975A (en) | 1976-09-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE22082T1 (en) | 9-THIOMAYTANSINOIDS, THEIR PRODUCTION AND USE. | |
| RO86698B (en) | Process for preparing (1-piperidinylalkyl)-pyrimidinone | |
| RO81225B (en) | Process for preparing some derivatives of 6-beta-hydroxyalkylpenicillanic | |
| UA5559A1 (en) | METHOD OF PREPARATION OF IMIDAZOLE DERIVATIVES | |
| RO81944B (en) | Process for the preparation of imidosulphamides | |
| RO72884B (en) | Process for preparing indolic compounds | |
| RO81766B (en) | Process for the preparation of phenylamines | |
| RO93218B (en) | Process for preparing 2-oxindole derivatives | |
| RO72547B (en) | Process for preparing 2',3,6'-trichloro-4-cyan-4'-benzoylureido-diphenyl esters | |
| RO81117B (en) | Process for preparing thiazolidenoxopropionitryl salts | |
| FR2369260A1 (en) | 2-1,5-DISUBSTITUTED 2-PYRROLIDONS AND THEIR PREPARATION METHODS | |
| RO66265B (en) | Process for preparing s-triazole-(3,4-b)-benzotmetathiazoles | |
| RO71183B (en) | Process for preparing substituited 20-on-steroids | |
| RO81686B (en) | Process for preparing triaryltriazole compounds | |
| ES420824A1 (en) | Triazole-bis(benzoxazole) optical brighteners | |
| FI852951L (en) | CHEMICAL SYNTHESES. | |
| ES535357A0 (en) | A METHOD OF PREPARING SPIRAL- (BENZOFURAN-AZALCANOS) | |
| FR2255895A1 (en) | Substd. benzo(b,d)pyrans - as anxiolytic, antidepressive and antipsychotic agents | |
| ATE10090T1 (en) | SUBSTITUTED 2,4-DIALKOXYBENZENESULFONYL CHLORIDES. | |
| RO78069B (en) | Process for preparing benzoyl-urea derivatives | |
| GB1516414A (en) | Prostane derivatives | |
| RO71480B (en) | Process for preparing diuretic and saluretic compounds | |
| GB622297A (en) | Improvements in or relating to the preparation of basic ethers | |
| RO86858B (en) | Process for the preparation of 2-phenoxypropionic acid derivatives of pentites | |
| RO85816B (en) | Process for preparing optically active 1-(6-methoxy-2-naphthyl)-2 -(alkoxycarbonyl)-amino-1-propanone derivatives |