RO72877B - Process for preparing optically active sulphur oxides - Google Patents

Process for preparing optically active sulphur oxides

Info

Publication number
RO72877B
RO72877B RO87985A RO8798576A RO72877B RO 72877 B RO72877 B RO 72877B RO 87985 A RO87985 A RO 87985A RO 8798576 A RO8798576 A RO 8798576A RO 72877 B RO72877 B RO 72877B
Authority
RO
Romania
Prior art keywords
optically active
preparing optically
sulphur oxides
active sulphur
general formula
Prior art date
Application number
RO87985A
Other languages
Romanian (ro)
Other versions
RO72877A (en
Inventor
Nickl
Original Assignee
Dr.Karl Thomae Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr.Karl Thomae Gmbh filed Critical Dr.Karl Thomae Gmbh
Publication of RO72877B publication Critical patent/RO72877B/en
Publication of RO72877A publication Critical patent/RO72877A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedeu de preparare a sulfoxizilor optic activi cu formula generala I: (vezi formula) în care R reprezinta grupa carboxil sau carbaloxi cu 2...7 atomi de carbon, caracterizat prin aceea ca, se aduce în reactie tioeter optic activ cu formula generala II: (vezi formula) în care R are semnificatia aratata mai sus cu perhidrol de concentratie 36% reactantii fiind luati în raport de greutate circa 3:1 la temperatura de 15...20 degree C, apoi amestecul de reactie care poate fi trecut sub forma de ester în mod obisnuit.Process for the preparation of optically active sulfoxides of the general formula I wherein R represents a carboxyl or carboxyl group of 2 to 7 carbon atoms, characterized in that an optically active thioether of the general formula II : where R has the significance shown above with 36% concentration of perhydrol, the reactants being taken in a weight ratio of about 3: 1 at a temperature of 15-20 ° C, then the reaction mixture which may be passed under the form of the ester is customary.

RO7687985A 1975-10-14 1976-10-12 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE SULFOXIDES RO72877A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752545947 DE2545947A1 (en) 1975-10-14 1975-10-14 Antithrombotic and hypolipaemic biphenylyl-ethyl sulphoxide - prepd. by oxidising optically active thioether cpds. (NL 18.4.77)

Publications (2)

Publication Number Publication Date
RO72877B true RO72877B (en) 1983-06-30
RO72877A RO72877A (en) 1983-07-07

Family

ID=5959111

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7687985A RO72877A (en) 1975-10-14 1976-10-12 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE SULFOXIDES

Country Status (15)

Country Link
JP (1) JPS532460A (en)
AT (1) AT346317B (en)
CS (1) CS189793B2 (en)
DD (1) DD127924A5 (en)
DE (1) DE2545947A1 (en)
DK (1) DK460776A (en)
ES (1) ES452351A2 (en)
FI (1) FI762726A (en)
LU (1) LU75981A1 (en)
NL (1) NL7611293A (en)
NO (1) NO763490L (en)
PL (1) PL103680B3 (en)
PT (1) PT65710B (en)
RO (1) RO72877A (en)
SE (1) SE7611375L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906658A (en) * 1987-04-21 1990-03-06 Merck Frosst Canada, Inc. Fluoro-sulfones
US7449481B2 (en) 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives

Also Published As

Publication number Publication date
JPS532460A (en) 1978-01-11
NL7611293A (en) 1977-04-18
ES452351A2 (en) 1977-12-16
PT65710A (en) 1976-11-01
DE2545947A1 (en) 1977-04-28
LU75981A1 (en) 1977-10-26
ATA667376A (en) 1978-03-15
RO72877A (en) 1983-07-07
CS189793B2 (en) 1979-04-30
AT346317B (en) 1978-11-10
NO763490L (en) 1977-04-15
DD127924A5 (en) 1977-10-19
SE7611375L (en) 1977-04-15
PL103680B3 (en) 1979-07-31
FI762726A (en) 1977-04-15
DK460776A (en) 1977-04-15
PT65710B (en) 1978-08-02

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