RO131825A0 - Multipurpose antimicrobial composition for industrial use - Google Patents

Abstract

The invention relates to a multipurpose antimicrobial composition used for preserving and treating wood. According to the invention, the composition consists, in mass percentage, of 10...35% 4,5-dichloro-2H-isothiazol-3-one, 0.01...20% co-biocide selected among permethrin, 2-octyl-2H-isothiazol-one, didecyl poly oxyethyl ammonium borate, N,N-didecyl-N-methyl-(polyoxyethyl) ammonium propionate and bis(3-aminopropyl)dodecylamine, 10...25% non-ionic emulsifier, 15...35% polar organic solvent, and, for the remainder, a non-polar organic solvent of the petroleum distillate type.

Description

MULTIFUNCTIONAL ANTIMICROBIAL COMPOSITION FOR INDUSTRIAL USE

The present invention relates to a multifunctional antimicrobial composition for industrial use, used in the preservation and treatment of wood in particular, but also of rubber, paints of all types, including those for vapors, leather, binders, insulation, metal processing fluids, cement, sludge / sludge, water from cooling towers, storage spaces for building materials, having fungicidal, bactericidal, insecticidal, algicidal, anti-vegetative effect.

The multifunctional antimicrobial composition for industrial use is a clear solution, slightly yellowish or reddish, with the density 0.91-1 g / cc, specific odor and is used as such, as an additive in rubber, paints, binders, insulation, processing fluids. metals, cement, sludge / sludge, water from cooling towers and in aqueous dispersion for the treatment of wood and storage spaces for building materials.

When choosing the components for formulating an antimicrobial composition, several factors must be taken into account: biocidal efficacy, compatibility / synergism of the components, specific consumption of the active substance, resistance to moisture and light / UV radiation, preservation of the antimicrobial effect over time, toxicity and ecotoxicity , costs, legal issues relevant to the type of biocidal product.

Compositions with fungicidal and / or bactericidal and / or insecticidal, antimicrobial and / or algicidal and / or anti-vegetative activity will be known as appropriate, based on one or more active, inorganic, organometallic, organic substances, such as: compounds ororganic and inorganic chromium, zinc, arsenic, iron, silver, boric acid as well as oxides and boron salts (borates), quaternary ammonium salts, amines and their derivatives, creosote, isothiazolones, carbamates, dithiocarbamates, triazoles, sulfamides, thiocyanates sodium, potassium thiocyanate, sodium arsenite, potassium arsenite or organometallics such as copper oleate, synthetic pyrethroids, of which we mention alpha, beta theta and zeta-cypermethrin, bifentrin, deltamethrin, dimethrin, permethrin, or a mixture of these.

The current trend in the field of biocides is the formulation of them with several active substances, with fungicidal and / or insecticidal and / or bactericidal and / or algicidal and / or anti-vegetative properties having synergistic effect, which leads to a multifunctional product, with a low consumption of the active substance, minimization of the impact on the environment and human health, as well as lower costs.

Such a product is the mixture between zoxamide and DCOIT / ILO, with the role of inhibiting the growth of microorganisms in building materials (WO 2014085742), by

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Information on mixtures of antimicrobial active substances (fungicides) such as: propiconazole-tebuconazole-imidachlorprid, iodopropinylbutyl carbamate (IPBC) - quaternary ammonium salts, 4,5-dichloro-2-n-octyl-3-isothiazolone (available) is available. ) - IPBC.

The most popular antimicrobial products for industrial use available on the market are fungicides for wood treatment, these being formulated mainly on the basis of IPBC, tebuconazole, propiconazole or their mixture.

The disadvantage of these products is the low concentration of active substances in the formulations, which implies the increase of transport, storage and labor costs, the limited use area and the high minimum inhibitory concentration.

The current market requirements are aimed at multifunctional antimicrobial products, with multiple uses and roles, which involve flexibility in operation, minimal consumption of active substances, low costs, minimal impact on the environment and human health, stability in the presence of moisture and solar radiation. .

Thus, an improved preservative composition, which is formulated on the basis of a chlorine-free isotiazolone (preferred being 1,2-benzizothiazolin-3-one), a co-biocide, preferably zinc or sodium salt of salt, is disclosed in U.S. Pat. N2-mercaptopyridine oxide (pyrithione) and an amine or amine derivative, which has the role of enhancing the biocidal effect of the system of active substances. The biocidal product thus obtained is used both in cosmetic and household products, as well as in varnishes, paints, inks, adhesives, processing fluids and certain construction materials.

The technical problems to be solved by the invention consist in the formulation of a multifunctional antimicrobial product for industrial use, with high biocidal efficacy, so with low minimum inhibitory concentrations, having a broad spectrum of action: bactericidal, fungicidal, insecticidal, algicidal and antifungal for treatment and wood preservation in particular, but also rubber, paints of all types, including those for ships, leather, binders, insulation, metal processing fluids, cement, sludge / sludge, water from cooling towers, storage spaces for building materials , especially the timber.

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In the particular case of wood, the bacteria do not produce significant degradation, but they prepare the ground for the attack of mold and insect, living in symbiosis with them.

The active antimicrobial (biocidal) substances used according to the invention, besides the efficacy of the bactericidal, fungicide, insecticide, algicide and antivegetative very high biocides, are stable in the presence of solar radiation, have a high resistance to washing with water, so in the case of wood treatment the protection will be very long; also the risk of their entrainment with atmospheric water, penetration into soil and migration into ground and groundwater is minimal. The multifunctional antimicrobial composition for industrial use is used in minimum concentrations of the active substance, which implies the reduction of costs and minimal impact on the environment and human health. Also, the product is formulated as a liquid concentrate, emulsifiable, being used in high dilution, which minimizes the emission of volatile organic substances.

The multifunctional antimicrobial composition for industrial use, according to the invention, consists of: 10 - 35% by weight 4,5-dichloro-2H- isothiazole-3-one (DCOIT), 0.01 - 20% by weight co-biocide selected from: permethrin , 2-octyl-2H-isothiazole-3-one (ILO), N, N-didecylN-methyl- (polyoxyethyl) ammonium propionate, didecylpoloxyethylammonium borate (polymeric betaine), bis (3-aminopropyl) dodecylamine (Diamine) or mixtures of these, 1025% by weight non-ionic emulsifier with HLB comprised between 4-13 of PEG type oleate / stearate / laurate, sorbitan oleate / stearate / laurate, alkylpoliglucosides, ethoxylated fatty alcohols, or mixtures thereof, preferably PEG oil / stearate / laurate , 15-35% by weight polar organic solvent selected from an alcohol / diol with 1-8 carbon atoms, ethers-alcohols, esters and the rest up to 100% non-polar organic solvent, petroleum distillates such as xylenes, toluene, ethylbenzene, white spirit , preferred being xylenes and ethylbenzene.

The following are 6 non-limiting examples of multifunctional antimicrobial composition for industrial use:

Example 1. In a mixing bowl made of stainless steel or with anti-acid protection, provided with heating / cooling jacket, electrically operated stirring and evacuation system, 100 kg DCOIT previously dissolved in 218 kg xylene and 12 kg are introduced under stirring. ethylbenzene, 160 kg PEG 400 monooleate with HLB 11, is supplemented with 240 kg isobutyl alcohol in which 100 kg permethrin and 10 kg diamine have previously been dissolved; add 160 kg xilen and stir well until a yellowish or reddish solution is obtained, with a specific odor and density of 0.91-1 g / ce.

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Example 2. In a mixing bowl made of stainless steel or with anti-acid protection, provided with heating / cooling jacket, electrically operated stirring and evacuation system, 200 kg DCOIT previously dissolved in 228 kg xylene and 12 kg are introduced under stirring. ethylbenzene, 130 kg PEG monolayed with HLB 12, is supplemented with 300 kg normal butyl alcohol in which 10 kg permethrin and 50 kg ILO have previously been dissolved; add 70 kg xylenes and stir well until a yellowish or reddish solution is obtained, with a specific odor and density of 0.91-1 g / cc.

Example 3. In a mixing bowl made of stainless steel or self-protection, provided with heating / cooling jacket, electrically operated stirring and evacuation system, 260 kg DCOIT previously dissolved in 273 kg xylene, 220 kg are introduced under stirring. PEG 200 monostearate and 30 kg alkylpolyglucosides with HLB 5 are supplemented with 180 kg isopropyl alcohol in which 37 kg of N, N-didecyl-N-methyl- (polyoxyethyl) ammonium propionate has been previously dissolved; stir well until a yellowish or reddish solution is obtained, with a specific odor and density of 0.91-1 g / cc.

Example 4. In a mixing bowl made of stainless steel or with antacid protection, provided with heating / cooling jacket, electrically operated stirring and evacuation system, 100 kg DCOIT previously dissolved in 260 kg xylene and 40 kg are introduced under stirring. ethylbenzene, 190 kg sorbitan oleate and 10 kg ethoxylated fatty alcohols with HLB 7, are supplemented with 200 kg of butyl acetate in which 100 kg permethrin and 100 kg diamine have been dissolved previously; stir well until a yellowish or reddish solution is obtained, with a specific odor and density of 0.91-1 g / cc. Example 5. In a mixing vessel made of stainless steel or with antacid protection, provided with heating / cooling jacket, electrically operated stirring and evacuation system, 300 kg DCOIT previously dissolved in 400 kg toluene and 50 kg are introduced under stirring. ethylbenzene, 90 kg of sorbitan laurate and 40 kg of ethoxylated fatty alcohols with HLB 9 are supplemented with 120 kg 2,2,4-trimethyl-1,3-pentadiol in which 0.5 kg of polymeric betaine have been previously dissolved; stir well until a yellowish or reddish solution is obtained, I have a specific odor and density of 0.91-1 g / cc.

Example 6. In a mixing bowl made of stainless steel or with antacid protection, provided with the heating / cooling jacket, electrically operated stirring and draining system, 350 kg 4,5-dichlor-2H-octyl-4 is stirred. -isothiazolin-3-one previously dissolved in 180 kg xylenes and 20 kg white spirits, 50 kg sorbitan stearate and 50 kg alkylpoliglucoside with HLB 13, supplemented with 300 kg methyl alcohol and 50 kg phenoxypropanol in which they were previously dissolved 0.1 kg diamine; stir well until a yellowish or reddish solution is obtained, with a specific odor and density of 0.91-1 g / cc.

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The minimum inhibitory concentration (MIC) for the compositions presented above are:

Microorganism type Comp.ex.l MIC mg / 1 Max. Comp.ex.2 MIC mg / 1 Max. Comp.ex.3 MIC mg / 1 Max. Comp.ex.4 MIC mg / 1 Max. Comp.ex.5 MIC mg / 1 Max. Comp.ex.6 MIC mg / 1 Max. FUNGI Aspergillus niger 0.7 0.35 0.27 0.7 0.23 0.2 Trichoderma viride 30 15 11.5 30 10 8.6 Ulocladium sp. 8 4 3 8 2.7 2.3 Run albicans 60 30 2. 3 60 20 17 ALGAE Anabaena flos-aquae 10 5 3.8 10 3.3 2.9 Nostoc common 10 5 3.8 10 3.3 2.9 Microcystis sp. 10 5 3.8 10 3.3 2.9 Chlorella pyrenoidosa 10 5 3.8 10 3.3 2.9 Scenedesmus Sp. 2 1 0.8 2 0.67 0.57 BACTERIA Bacillus subtilus 20 10 7.7 20 6.7 5.7 Escherichia coli 180 90 69 180 60 51 Pseudomona aeruginosa 140 70 54 140 47 40 Staphylocco cus aureus 50 25 19 50 17 14

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The multifunctional antimicrobial composition for industrial use is used in dilution of 0.7-3% for wood preservation and 0.1-1% for the other recommended uses.

Claims (5)

1. Multifunctional antimicrobial composition for industrial use with high biocidal efficiency, having a wide range of action: bactericide, fungicide, insecticide, algicide and antivegetative for treating and preserving wood in particular, but also rubber, paints of all types, including those for ships, leather, binders, insulation, metal processing fluids, cement, sludge / sludge, water from cooling towers, storage spaces for building materials, having a fungicidal, bactericidal, insecticidal, algicidal, anti-vegetative effect, characterized by being constituted from 10 - 35% by weight 4,5dichloro-2H- isothiazole-3-one (DCOIT), 0.01 - 20% by weight co-biocide selected from: permethrin, 2-octyl-2H-isothiazole-3-one (ILO) , N, N-didecyl-N-methyl- (polyoxyethyl) ammonium propionate, didecyl polyoxyethyl ammonium borate (polymeric betaine), bis (3aminopropyl) dodecylamine (Diamine), 10-25% by weight non-ionic emulsifier with HLB between 4-13 of PEG type oleate / stearate / laurate, sorbitan oleate / stearate / laurate, alkylpolyglucosides, ethoxylated fatty alcohols, 15-35% by weight polar organic solvent selected from an alcohol / diol with 1-8 carbon atoms, ether-alcohols, esters and the rest up to 100% nonpolar oranganic solvent, petroleum distillates selected from xylenes, toluene, ethylbenzene, white spirit. 2. The multifunctional antimicrobial composition for industrial use according to claim 1, characterized in that the co-biocide is selected from permethrin, 2-octyl-2H-isothiazole-3ona (ILO), N, N-didecyl-N-methyl- (polyoxyethyl). ) propionate ammonium, didecyl polyoxyethylammonium borate (polymeric betaine), bis (3-aminopropyl) dodecylamine (Diamine) or mixtures thereof. 3. The multifunctional antimicrobial composition for industrial use, according to claim 1, characterized in that the emulsifier used in the composition is non-ionic, with HLB ranging from 4-13 of PEG type oleate / stearate / laurate, sorbitan oleate / stearate / laurate, alkylpolyglucosides, alcohols. ethoxylated fats, or mixtures thereof. 4. The multifunctional antimicrobial composition for industrial use according to claim 1, characterized in that the polar solvent is selected from an alcohol / diol having 1-8 carbon atoms, ethers-alcohols, esters or mixtures thereof. 5. The multifunctional antimicrobial composition for industrial use, according to claim 1, characterized in that the non-polar solvent is an oil distillate selected from xylenes, toluene, ethylbenzene, white spirit or mixtures thereof.