RO126272A0 - Set of elements and medical device meant to slow down tissue resorption - Google Patents

Abstract

The invention relates to a set of elements and medical devices meant to slow down tissue resorption in patients in which implant-prosthetic rehabilitation of teeth has been performed. According to the invention, the set includes a dental implant comprising an upper end provided with a central rod (1), made of titanium alloys, at a lower end of said rod (1) there being placed a self-threading leading tip (2) provided with a single or multiple-thread cutting screw (a1) and some cutting teeth (a2), a central jacket (3) preferably made of zirconium oxide which envelopes the rod (1) at a certain distance, so that a small empty space (a4) can exist or not between the jacket (3) and the rod (1), wherein a composition as powder or a tubular piece (4) to accelerate osseointegration is introduced, and a prosthetic blunt (5) placed within a recess (b3) of the upper end of the rod (1) on which a dental crown is made, as well as a composition for accelerating implant osseointegration, made of some substances normalizing the exchanges at the level of the cellular membrane and regulating the enzyme exchange, various implant elements and medical devices to be made of and with said composition.

Description

Set of medical elements and devices for slowing down tissue resorption

The present invention relates to a set of medical elements and devices intended to slow down the resorption of tissues in persons in whom the dentition has been rehabilitated implant-prosthetically. The set is also intended for people who have not had teething problems and want to maintain a healthy natural dentition and, finally, certain elements and devices in its composition can be used by people who have already been inserted before. , any other type of dental implant, those suffering from chronic periodontopathy as well as those to which tissue resorption is due simply to the effects of aging.

The principle underlying the invention is successfully used in dentistry but it is obvious that it can be used in other fields of medical sciences in this regard, the dental set, according to the invention, includes a dental implant - specially created for this purpose - a composition for accelerating its osseointegration, as well as various implant elements and medical devices achievable from and with this composition. All the objects of the set, taken together, or each of them taken separately, have, under certain conditions, the role of slowing down the resorption of tissues.

In the present case, the element means a single product made only of the composition, such as a little free powder of the compositions or the powder pressed in a filiform form or very small tubes of different shapes and sizes usable as such during medical documents. By device is meant a unitary assembly made of several parts and distinct elements such as, for example, the implant itself or a complex assembly that includes the composition, a support for it and, possibly, a heating system.

It is well known that in all people who have had dental implants inserted or are to be inserted, a resorption of the tissues, gums and bone structure affected by the implant occurs over time. However, resorption occurs - continuously - in people affected by chronic periodontopathy as well as in the elderly. The reason is due to the decrease of blood microcirculation in the respective tissues and has as final effect the appearance of dental mobility, if we refer exclusively to the teeth. Normally, however, dead cells should be immediately replaced with new, progenitor cells that turn into cells specific to that area, osteoblasts, cementoblasts, and so on. The decrease in blood microcirculation also has, for example, the effect of wrinkles on the face of the elderly. The dead cells are no longer evacuated and replaced but remain in the area leading to the appearance of wrinkles. As already mentioned, the set according to the invention is intended to slow down the appearance of these effects.

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In order to speed up tissue healing, an electronic device is known that generates a low frequency electromagnetic field - WO 2009/04215 A1 - which is part of a set for healing tissues and bones with various diseases. The device generates a magnetic field and is equipped with an electric circuit to control the pulsation of the magnetic field.

In order to solve the problems of partial edentation are also known and applied a wide variety of forms of metal implants usually made of titanium, more or less alloyed, because it is quite well tolerated by the human body, is easily workable, has a good mechanical resistance to compression, torsion and bending and, consequently, allows the realization of composite dental implants, also called "two-stage surgery", which have the advantage of giving the doctor the opportunity to choose the type of prosthetic work favorable to the patient. the hibernation period necessary for the integration of the implant and favors the installation of parallel prosthetic abutments on which dental crowns perfectly adapted to the respective case can be made.

Subsequently, several researchers have found that the osseointegration time of an implant decreases when it is made of a ceramic material, more precisely of zirconium oxide, because, compared for example with titanium, it is much better tolerated by the body and at the same time, it has the quality of not favoring the formation of electric batteries even if it is combined with various other metals. Basically, there are only a few patients allergic to this material, it being both biocompatible and bioinert. Then, zirconium is also preferable in terms of thermal conductivity. It does not conduct heat so thermal variations are not transmitted to the alveolar bone. This is extremely important especially when the implant needs to be adjusted by grinding right in the patient's mouth. In addition, even if it does not conduct heat, zirconium oxide conducts perfectly well the low frequency secondary oscillations produced by the minerals inside the implant.

We must also add here the fact that both titanium and zirconium, with their alloys, are materials frequently used in implantology, because both have the property of not inhibiting the growth of osteoblasts, cells essential for bone integration.

Given the superior qualities of zirconium oxide, in terms of osseointegration, it was sought to make composite implants, so with implantation in two surgical stages and this material. Unfortunately, this has not yet been possible due to the low machinability of zirconium oxide, which has the effect that certain fineness operations, including threading, cannot be carried out in an optimal way for the time being, as in metals.

However, the use of other types of materials, which have superior osseointegration qualities to titanium, does not always give the expected results due, not only

4 ^ 2010-01910-2 5 -10- 2010 their relatively low machinability but also due to their modulus of elasticity which is often in contradiction with the elasticity of the jaw or mandible portion in which the implant is to be inserted. For example, it is well known that in their anterior part, both the jaw and the mandible are harder, because here the bone density is higher, and in the posterior part both the jaw and the mandible are more elastic, because the porosity of the bone is more big. For this reason, the elasticity of the implant must be adapted to the elasticity of the part of the jaw or mandible in which it is to be inserted, which is not always possible because if titanium has a certain elasticity, zirconium oxide is a hard and friable ceramic material.

Returning to zirconium oxide, its low machinability makes it very difficult, virtually impossible, to obtain from it composite implants, but easily made from titanium alloys, which are recommended by most clinicians. Consequently, materials with increased biocompatibility, such as zirconium oxide and other ceramics, do not allow obtaining a self-tapping area at the top of the implant or the creation of an internal thread, resistant over time, through which to make the connection between the prosthetic abutment and the implant itself. As such, zirconium oxide implants are usually made in the form of a single landmark - which is why they are also called monobloc implants, and the construction of the dental crown on them is very difficult. And this is because, on these implants, we can only make cemented works, at present it is practically impossible to make threaded works. This is very important especially in the case of dental bridges, the risk of allergy when using zirconium is much lower.

Until now, it has not been possible to make viable implants that combine the machinability and mechanical qualities of titanium with the biocompatibility of zirconium.

A brief review of those made so far by researchers in the field will be made below in order to better highlight the new elements introduced by the present invention.

Returning to metal implants, based on titanium alloys, these, unlike ceramic ones, can be easily provided with an internal thread at their top, (RO121362B1; GB2210795A), to fix the prosthetic abutment by screwing , ^; qr on the outside can be made any type of thread or processing that allows good primary retention. In addition, some of them are provided with a self-tapping head which allows them to be inserted more easily into the alveolar bone. However, although extensive research and application has shown that titanium-based alloys are relatively well tolerated by the human body, there are also situations where they create problems, for example, in patients with metal intolerance. whose number is, unfortunately, constantly growing. Another important disadvantage of this type of implants, metal, is

during the relatively long time required for their osseointegration into the alveolar bone and the possibility of forming an electric battery.

Ceramic implants - and we refer here again to those made of zirconium oxide - although better tolerated by the body, can not be provided, on the outside, than, at most, with a simple threaded pattern, rounded, to allow an anchorage their best in the alveolar bone.

We can mention here the implant described in patent application WO 2006/108951 entitled Screw implants. As a form, this implant is, in general, very simple and relatively easy to make, but in addition to advantages it also has quite large disadvantages as it results from the research carried out by the author of the present invention, research presented briefly in the analysis below .

Thus, the author conducted a research on cell cultures of fibroblasts and was able to demonstrate the superior biological characteristics of zirconium oxide, compared to titanium, in terms of biocompatibility. The study was conducted at the Faculty of Biology of the University of Bucharest together with Ms. Anișoara Câmpean, associate professor and was presented at the Biology Congress in Vienna in 2008, where it enjoyed attention.

Also, the author conducted a clinical study published in "Revue Implantologie" November 2007 pages 103-108, a study that demonstrates the good integrability of zirconium oxide. The implants used for this study were monobloc. The author also highlighted the prosthetic problems that may occur when using this type of implant, including the difficulty of being able to offer a hibernation period of about three months. This derives from its very construction because the prosthetic abutment, of obvious type or, in other words, apparently, from the oral cavity, will always be touched by food and tongue, during mastication, which can cause the implant to reject due to its continuous microdeplacement. . The study also showed that even when monobloc implants are integrated, major problems occur due to the non-parallelism of the abutments. However, in order to achieve the parallelism of the abutments, they must be further sanded, which can generate the appearance of microcracks that, in time, can cause the abutment to break. Obviously, this forces us to resect the entire implant, because the abutment can no longer be changed.

Turning to composite implants, also called "two-stage surgery", but usually made of titanium and its alloys, we can say that, in many ways, these implants are superior to monobloc zirconia. This, first of all, because each piece and detail of the assembly has a certain functional role, which allows the realization of screwed prosthetic works which, in turn, allow obtaining in the laboratory a good parallelization of the prosthetic abutments.

Starting from all these findings, we tried to make dental implants, also called hybrids, which combine two materials, each with certain specific qualities, in order to gain from each the qualities it has.

For example, patent application PCT / FR00 / 02008 (WO 01/05325 - DENTAL IMPLANT COMPRISING TWO BIOCOMPATIBLE MATERIALS) relates to a dental implant made of two materials with equal biocompatibility but having a different osseointegrability, namely, some elements of a ordinary titanium alloy and other porous titanium elements. The implant is made in the form of a central, elongated body, provided with two axial holes, centrally clogged, one at each end. A porous titanium rod is inserted in the hole at the lower end and the prosthetic abutment can finally be screwed into the one at the upper end. A porous titanium sheath is inserted along the central body, towards the upper end. The role of porous titanium is to promote the entry of osteoblasts inside it, thus ensuring a better integration of it in the alveolar bone. To make it easier to insert the implant into the newly created alveolus, its lower end is threaded to the outside. However, it is noted that only a relatively small area of the porous titanium layer comes into contact with the bone and the insertion of the porous titanium mantle on the body ^{: the} implant is practically very difficult.

The embodiments are slightly different from each other and, as such, the general case is that, inside, these implants, in two surgical stages, existing on the market, are usually provided with a longitudinal-axial hole, threaded at its upper end, in which the scarring abutment is to be inserted first, then, after approx. 2 to 3 months after implantation, the healing abutment and, finally, after a shorter period of time, the prosthetic abutment. It is obvious, however, that this type of implant, in two stages, but made of titanium, has the disadvantage of the relatively long time required for osseointegration in the alveolar bone, which can lead, in the end, to some complications that may delay the fixation of the prosthetic abutment and dental crown.

Due to the impossibility of making a thread on a piece of zirconium oxide, an attempt was made to obtain prosthetic abutments to be fixed in the implant body through a con morse system, with a slope of approx. 2 degrees, the assembly will then be cemented with a dental cement.

This combination has the great disadvantage that it can no longer be disassembled in case of various accidents that may occur over time - abutment fractures, misalignment of abutments, blocking of the abutment in an incorrect position, before reaching the final position - relatively common accidents in implantology . in addition, it must be acknowledged that, over time, the cementation may fail and, as a consequence, we can no longer correctly reapply a new abutment, due to the remaining traces of dental cement.

No other materials with increased biocompatibility - such as porous titanium - allow threading and, therefore, their insertion is done only by impact.

However, this system is not accepted by most dentists.

As an exception to the above, by patent application PCT / WO 99/17675 entitled 'Zirconium oxide dental implant with internal thread', the author seeks to resolve the already known impediments. Knowing the difficulty of making threads in zirconium oxide, he proposes a solution for casting zirconium in the mold to make this type of thread. However, the results obtained were not in line with expectations, which did not allow the solution to spread.

in orthopedics, in general and in dental implant surgery, in particular, it is of decisive importance to reduce the healing period of the fractured bone, respectively the biointegration of the implant. The use of porous titanium, zirconium oxide, alloying titanium with zirconium to obtain roxolid, are just some of the solutions applied.

Later, however, starting from various researches, new elements were discovered that opened the way for the application of new solutions. Thus, it is obvious that the level of tissue integration depends, first of all, on the speed with which the new cells arrive in the area destroyed by the surgical trauma. If the flow of these cells is high, there will be a rapid neovascularization of the area and the cells will be able to survive on the implanted material. This can reduce the layer of protoglycans and increase the percentage of direct osimplant contact. Patent application FR 2919498, dated 02.08.2007, belonging to Mr. Gilles Gutierez, presents a first use of opal in medicine, more precisely in cosmetics, following the discovery of the effect that both natural and synthetic opal have to produce increasing the migration rate of progenitor cells used in cell cultures (keratinocytes and fibroblasts).

It should be noted that patent application JP2009254547 (A) of 2009-11-05 also highlights that a composition that includes octacalcium phosphate can successfully contribute to bone regeneration. In general, research conducted by many specialists has shown that there are many other substances that, in fact, normalize exchanges in the cell membrane and regulate enzyme balance.

Patent application FR 2926460, dated 22.01.2008, having as authors Messrs. Gilles Gutierrez and Bogdan Vlădilă, the author of the present application - both from GINGIVAL PROTECT, Bucharest, Romania - presents, however, a first medical use of opal in dental surgery , in order to accelerate the growth of the mass of bone material arranged around an implant or the root of a tooth. For this purpose, a composition is made which includes natural or synthetic opal - in a proportion of 0.5 to 20%, but preferably between 1 and 10% - embedded in a mass of easily polymerizable or fusible polymeric material. By ο ¹ α - ο 'ο ι ο - 2 5 -II) - 2010 Δ7 the research carried out by the two authors found that the existence of opal in this composition causes a migration of cells, especially those of osteoblasts, cementoblasts, fibroblasts or keratinocytes. almost three times larger than in his absence. With others: twenty solutions can be applied in the field of dental implants to successfully improve the integration of the implant in the alveolar bone.

The same authors subsequently registered, on July 10, 2008, also in France, under no. 08 03921 / CBI 2933610 a new patent application entitled "Opal-based composition for the treatment of dental diseases" which relates to a composition which includes an opal powder which is incorporated into a mass of hot melt polymer chosen from polyolefins such as polyethylene or polypropylene, alone or in a mixture. From this mixture you can get a shape, individualized to each patient through a dental brace, for periodontal regeneration. The results obtained, mentioned by the two authors in the application, are very promising. It should be added here that the application of the solution continues even now and the results are remarkable. The author of the present invention has so far treated over 100 patients - using such a splint - patients whom he has examined together with other renowned dentists in Europe.

Also, working together with Mr. Gilles Gutierrez obtained confirmation that cell migration occurs even if there is no direct contact between the opal - or a composition that includes opal - and the affected tissue. However, this migration is influenced by several factors, including the patient's oral hygiene, his age, the material between the opal and the affected tissue and the opal concentration of a particular mixture. Then it was shown that neither titanium nor zirconium prevents too much the signal transmitted at a distance from the opal, a signal that determines the migration of cells. However, zirconium transmits this signal to a greater extent than titanium. It has been hypothesized for the first time that the Brownian motion inside the opal composition may be the one that generates a certain type of signal that causes migration to begin, because cell migration begins as soon as the opal is attached to a cell culture. We can now explain the previously issued hypothesis because cell cultures are performed at temperatures above 37 ° C. This means that these crystals take up heat and secondarily emit low frequency oscillations that cause the cells to attract. Even if, for a certain type of implant, the surface occupied by zirconium oxide cannot be too large, it is still good to create it because it is the one that will favor the transmission of the signal generated by the active substance introduced inside the implant much better. than any other metal.

Also, these experiments showed that the tooth itself naturally emits a signal that attracts the progenitor cells in order to regenerate what is destroyed by Χ- 2 Ο 1 Ο - Ο 1 9 1 ο - 2 5 -10- 20W cause of microbial activity. However, the intensity of this regenerative signal decreases with age and the tartar completely shields its intensity.

If, as it was found as a result of research conducted, among others by the two researchers, the teeth show a weak signal, autologous, regeneration, current implants, unfortunately, do not generate this type of signal, which is why they are much more vulnerable to degenerative agents (microbes, chemicals in food, occlusal pressures). It is therefore necessary to add this type of signal to the implants by introducing active substances, such as those mentioned above, either inside the implant or outside it, in order to create the condition for these implants to withstand degenerative actions. However, it is very important that zirconium oxide is a much better signal transmitter than titanium. For example, when using zirconium oxide, the signal strength is strong enough to attract the progenitor cells to the implant even if only 5% of the implant mass is represented by active substances such as, for example, opal or calcium carbonate, over time. what for titanium requires a proportion of at least 20% of the implant mass. Research has also shown that the signal is very well transmitted under the conditions of sterility existing inside the alveolar bone where we will insert the implant, here there are no microbes, although in the oral cavity, these microbes exist. This fact was demonstrated by the author working in collaboration with the Victor Babeș Institute in Bucharest. Given the fact that the gum and bone form a unitary whole, it is obvious that gingival regeneration is also applied to the bone, due to cellular plasticity that determines the transformation of progenitor cells, either into osteoblasts or fibroblasts. The results of this study were communicated to researchers who participated in the Europerio 6 international congress, held in Stockholm in 2009.

State-of-the-art research, corroborated with the results of older research, opens up new avenues, completely unexpected in dental implantology. Thus, in 1952, Dr. Winfried Otto Schumann, from the Faculty of Science in Munich, managed to prove an older theory, namely that the terrestrial space between the earth's surface and the ionosphere behaves like a waveguide and also like a sounding board. The frequency spectrum of this space is approximately between 6 and 50 Hz with the main value, average, of 7.83Hz. Because life on earth was created inside this space, everything we call a living organism has adapted to this frequency. The vital functions of the organisms deteriorate in the longer absence of this frequency. This is why the body of cosmonauts suffers significant disorders during space flight, for example periodontopathy. However, things started to normalize after the 7.83 Hz frequency was generated on board the spaceships ο- 2 Ο 1 Ο - Ο 1 ΰ 1 Ο - - / Ζ

5 -10- 2010 artificial. Deepening the research, scientists have found that in addition to the basic frequency, vital for the functioning of any organism, the internal organs and the cells of which they are composed react favorably to other frequencies, some of them vital for their recovery if they were subject to injury or if they suffer from certain conditions.

Thus, it was demonstrated by James L. Oschman (see his papers: Energy Medicine - The Scientific Basis; Energy Medicine in Therapeutics and Human Performance; Recent Developments in Energy Medicine) that every normal or pathological event occurring within any organism produces changes in the electromagnetic field generated by that organism. Based on these principles, devices have been built that manage to monitor the activity of the heart, brain or to specify the time of ovulation. Oschman also demonstrated that muscle activity generates electromagnetic impulses that stimulate cell regeneration starting from the attraction of undifferentiated mesenchymal cells. He also showed that any condition - in our case periodontitis, or injury, in our case the damage caused by surgery at the time of implant insertion - causes a change in the magnetic field in that area. Based on all these findings, a new treatment has been developed called "pulsed electromagnetic field therapy" which treats bone fractures that do not heal.

Thus, Sisken and Walker demonstrated that the frequencies of 2 Hz, 25 Hz and 50 Hz stimulate nerve regeneration which is also useful in implantology if hypoaesthesia occurred after surgery, and a frequency of 7 Hz stimulates bone regeneration; this fact is also useful in dental implantology for better integration of implants. A frequency of 10 Hz stimulates ligament regeneration, which is useful in periodontics to reduce tooth mobility. It is obvious that a device that would emit this frequency can also act on the coexisting teeth. It has also been shown that the frequencies of 15 Hz, 20 Hz and 72 Hz stimulate the reformation of capillaries necessary action after any surgery of bone graft or soft tissue.

Herbert Frachlich demonstrated that “A set of cells that form a tissue or an organ has a specific frequency that regulates the physiology of that organ. If a large number of cells are affected then the frequency can no longer be emitted and disease or dysfunction occurs. ” The conclusion that can be drawn from this is extremely important. It follows that the human tooth itself, healthy, helps maintain the health of the area around it. Unfortunately, in the oral cavity the natural regenerative field is low because the microbial bodies and minerals in the composition of the tartar steal from the intensity of the regenerative field to mineralize.

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But how does gingival regeneration affect microbes in the mouth?

The explanation is very simple; they are electrically charged, either positively or negatively. These microbe charges destroy the ionic balance and thus periodontopathy occurs.

The frequency normally generated whenever a patient drinks warmer fluids is consumed partly for periodontal tissue regeneration and another part for tartar formation. Often, if the tartar already exists in large quantities, the frequency is distributed predominantly for the formation of tartar and no matter how many hot liquids we drink, there is not enough power from our own regenerative field to regenerate the tissues. Hence the importance of periodic removal of the formed dental tartar, so each individual must pay much more attention to his oral health.

It is therefore necessary to increase the amount of mineral capable of radiating infrared under the action of body temperature. Also a large part of the additional amount brought by the use of medical devices will continue to be stolen by the tartar which will settle faster. This was highlighted by the author of the invention who had to perform more frequent descaling of patients using such slides. This clinical observation confirms the theory described in this patent. We will introduce the minerals in the presented medical devices and we will have a low frequency secondary emission that can be distributed to tissue regeneration or in other words we will obtain a regenerating field that will help the body's natural field in slowing down tissue resorption. However, these microbial bodies and various harmful minerals are always present in large quantities in the oral cavity and can never be completely removed. It turns out that we should make medical devices that are easy to use and support, for a longer or shorter time by, for example, a patient with a dental implant or various periodontal problems. Adding a field with the highest possible frequency oscillations in resonance with the biological frequencies will reconstitute the regenerative frequency and will attract undifferentiated mesenchymal cells. They will start the physiological process of regeneration and will maintain it throughout life through applications at intervals completed by the doctor. Also, the frequencies applied by the doctor may be different depending on the desired result and the nature of the work - surgical or maintenance.

But if, for example, it is relatively easy to attach an electronic medical device to a fractured limb that generates - electronically - a favorable frequency for its recovery, it is obvious that no patient with a dental implant or periodontopathy will be able to hold in the mouth this device - for months - until the complete recovery of the affected tissues.

(Χ-2 01 Ο - 0 '3' - 2 5 -10- 2010

However, the solution came unexpectedly and was due to a clinical observation of the author of the present patent description. Thus, he found that some patients no longer part with the splint that they were recommended to wear only until the complete resolution of the dental problems for which they were instructed to wear it. Asked why she still wears it, even though the problems they had had had already been solved, they answered either that they found that wearing it calmed them down and / or that wearing it could put them to sleep better at night.

We remind you that these gutters are the subject of a previous patent application already mentioned above (no. 08 03921; CBI 2933610).

The explanation is that various minerals or crystals, such as opal, generate more or less intense electromagnetic fields in a range of frequencies beneficial to the human or animal body in general. It is clear, therefore, that a gutter made, for example, of a composition containing opal will emit, under certain conditions, electromagnetic radiation, in a range of frequencies favorable to operation and restoration not only of the tests immediately adjacent to it but even of proper operation. of the brain. Moreover, it is known that the use of crystals regulates the emitted frequencies, which is why they are used in television and broadcasting.

However, it is clear that such a device will do well, for example, on the skin of the face, generating an anti-aging effect as well as on the sinuses, eyes, etc. Patients who have become accustomed to sputum therefore realize that by wearing it and they feel good in many ways. It follows implicitly that the simplest way to apply these frequencies in the body is to ask the patient to wear almost all the time and mainly at night, a device made of a material that generates low, secondary frequencies, following thermal stimulation.

In other words, it is no longer necessary to create electrical devices capable of emitting electromagnetic frequencies beneficial to the human body, but it is enough to create static devices that include minerals capable of emitting these frequencies by taking energy from the human body to activate them. In fact, the clay treatments consisting in its application on the gums of the teeth affected by periodontopathy, although unpleasant in many respects, still give apparently miraculous and incomprehensible positive results for most doctors. The explanation is simple and is due to the fact that the microparticles of silicate in the clay, activated by the heat of the mouth, emit electromagnetic radiation beneficial to the body. The same goes for sitting on the beach on the sand. Children prefer to play in the warm sand and because, instinctively, they feel that it is good for them. Another important clinical observation refers to the fact that an anti-inflammatory effect is found in those who are exposed to the sun on the beaches formed by volcanic rocks - joint and rheumatic pains decrease. The same thing happens with the treatments in which pieces are put / (fî f (s> b

Λ-20 10-01010-2 5 -10- 2010 hot volcanic rock along the spine to relieve back pain, or any treatment that uses certain crystals heated to a fairly low temperature. There are currently a lot of treatments with various crystals placed, warm, on the affected body parts. Suddenly, a series of observations made by scientists get a simple explanation. For example, it has been found that those who consume hot foods or drinks - teas, soups - are less affected by dental problems. A reference study in dentistry published in 1986 in JOURNAL OF CLINICAL PERIODONTOLOGY ”no. 13, pp. 431 - 440 by Loe H and Anerud A show how Sri Lankan tea growers, who do not follow dental hygiene rules at all but consume a lot of hot tea, do not have special problems of peridental tissue resorption. Another longitudinal study conducted in Sweden shows that patients with very good hygiene but who consume cold foods have major problems with resorption of peridental tissues - JOURNAL OF CLINICAL PERIODONTOLOGY ”no. 28/2001, authors Rosling, Serina, Lindhe “Longitudinal periodontal tissue alteration during p therapy therapy”. Another finding, which until now seemed quite strange, is that in horned animals, such as reindeer and deer, the horns do not grow in the cold season. They begin to rise only when the outside temperature reaches the value of approx. 20 ° C. In other words, it is the heat that causes, for example, crystals in the dental structure or other bones or horns to emit high and / or very low frequency electromagnetic waves favorable to the neighboring area. In Sweden, people with various ailments can take part in medical treatments in warm baths with broken reindeer horns. It is scientifically proven by researchers at the University of Gratz that salt crystals have a therapeutic action due to the vibrations generated. It is also presented on - http://products.mercola.com/himalavansalt/bath-salt.htm - the opinion that the positive effect is due to the vibrations present when the patient bathes in a bathtub in which we have a lot of natural salt at constant temperature of 37 ° C. It is estimated that the water temperature must be constant for the vibrations to have a constant frequency. This scientifically proven application also applies to the oral cavity where the salt crystals will emit these frequencies normalizing the affected cell balance due to ionic changes caused by the appearance of microbes that are electrically charged. The mechanism described by us is different from the mechanisms used in all other salt crystal treatments because the treatments already described are based on the contact of salt with the cells - antiseptic effect and pH regulation. Our treatment means that the salt remains trapped inside the medical devices and we have no risk of overheating the salt in case of a prolonged treatment, mandatory to slow the resorption of tissues. Natural salt crystals are preferable to table salt which has already been processed and, as a result, its crystalline structure has been altered. These crystals take heat from the oral cavity and generate small amplitude oscillations with a regenerating role and slowing down the resorption of adjacent tissues. Another example is demonstrated by toothpaste manufacturers who show that after brushing the regenerative effect lasts about an hour. In fact, the restoration of dental tissues occurs due to the heating of minerals in the composition of the tooth and toothpastes and the emission of oscillations with low frequency.

in the book - http: //www.shirleys-wellness-cafe.eom/saltresearch.htm#Fact7 - Water and salt Essence of life ”- it is presented that salt crystals can generate the frequency that regulates tissue physiology.

There are studies that show that the calcium ion resonates at a frequency of 33.3 Hz. Or this ion is present in the composition of each dental and peridental tissue. These oscillations of mineral particles can exist by the action on them of electromagnetic waves frequently emitted by various artificial sources, which put them in a state of synchronous oscillation, on specific, biocompatible, beneficial frequencies.

Dr. David Cohen's therapy research (http://newyorkbodyscan.com/mineral-infrared-therapy-theory.html,) is also known in this regard, which highlights the bioenergetic effect of infrared radiation emitted by various minerals, as secondary radiation. which-absorbed by biological tissues, shortens the post-operative and post-disease recovery period. Experimental results in this regard were also obtained by K. Imamura in 1991 who placed plants in tap water, plain and in tap water in which he placed some minerals, found that, after three weeks, the plant in untreated water it was dry while the mineral water plant was still green. It was thus concluded that infrared emission, in the wavelength spectrum: 2,000-25000nm, has beneficial vibratory effects on ions in the cell membrane, balancing ion exchange between the outside and inside of the cell and making the cell membrane more permeable to nutrients, which prolongs the life of the cell. This effect is also manifested in animal and human tissue cells, as research has shown.

We find, therefore, that while some researchers believe that only extremely low frequencies, ranging from about 2 to 80 Hz, have favorable effects on the human body, other researchers believe that only infrared frequencies have these beneficial effects. What is certain, however, is that both groups of researchers highlight the beneficial effects generated by various crystalline minerals, put in contact with the human body. Another observation that can be made is that these favorable effects are triggered by heating the respective minerals or crystalline substances at a temperature above the human body, for example at approx. 50 ° C and subsequent contact with the human body. It can be # 4 <^ - 2010-01010--

5 -10- 2010 therefore concluded that the temperature jumps applied to a crystal or a composition that includes certain crystals, followed by their maintenance at a constant temperature of the human body are favorable to the generation of beneficial frequencies the human body.

Summarizing the above, we can say that titanium, with its alloys, as a metal used in implants, has the advantage of machinability and greater elasticity, zirconium oxide has, among other advantages already mentioned above, that of biocompatibility and as such an implant - called, by us, a hybrid - that manages to combine these two metals will be clearly superior to one made only on the basis of titanium or zirconium. It is also obvious that if the ratio of zirconium to titanium increases, its biological qualities will also increase, ie, e.g. osseointegration. Then, compositions capable of emitting very low frequency oscillations such as compositions based on opal, topaz, quartz, jade, orthorhombic calcium carbonate, octacalcium phosphate or other active substances in this respect known and already applied at present on world plan, or to be developed later, inserted in the implant or adjacent to it - ensures the recovery of nerves and tissues affected by surgery, alveolar bone and a better and faster osseointegration of any implant. In other words, it can be said that a hybrid implant which, at the same time, can also include a composition which generates, for example, biocompatible waves or which helps to heal affected tissues, nerves or parts of bone, acquires the property of regenerative implant, with active osseointegration.

It is also obvious that varying the ratio between the mass and the shape of the parts of an implant made of titanium alloys and those made of zirconium oxide used to make the same implant also varies its elasticity. As such, an implant adapted to the portion of the jaw or mandible in which it is to be integrated can be made.

The technical problem solved by the present invention consists in the realization of a set of medical devices which, based on the latest research in the field, contribute to the slowing down of tissue resorption both in persons to be fitted with dental implants but also in persons who have been fitted. already, previously, any other type of dental implants, to those suffering from chronic periodontitis as well as to those to which the resorption of tissues is due, simply to the effects of aging.

Extending the problem, the set will have to include a dental implant that allows the combination of the favorable characteristics of the three elements mentioned above, namely the machinability of titanium and its alloys with the biocompatibility of zirconium oxide and accelerating the recovery of affected tissues. due to the possibility of incorporating inside it, or attached to it, one or more implant elements, respectively medical devices made of a composition, or which include a composition, which stimulates the progenitor cells and ¢ ^ -2010- 01310--

5 -10- 2010 produces the restoration of all affected tissues. At the same time, the implant must allow its elasticity characteristic to be correlated with that of the part of the jaw or mandible in which it is to be inserted.

The dental set intended to slow the resorption of tissues, according to the invention, eliminates the aforementioned disadvantages and solves the proposed technical problem by including a dental implant made of a central, outer, revolutionary body - or in other words, the outer mantle - preferably made of -a ceramic material with high osseointegration such as zirconium oxide, or roxolid, a body that axially includes a central rod or, as the case may be, a central core that has the role of first taking over the torsional stresses produced when the implant is inserted into the bone alveolar and then those due to mastication, the rod being provided, respectively the central core being provided, for this purpose, with a threaded or other location in which the prosthetic abutment can be fixed, said rod or the central core being fixed inside the central body by screwing, gluing, welding, anchoring pin, morse taper, or any other means that allows a solid anchoring of their p it is the axis of revolution of the central body. On a case-by-case basis, the body can also be provided with a central space in which various biologically active compositions can be arranged. At its lower end, below the central body, the rod may or may not be provided with a self-tapping head. The central rod / central core and the self-tapping head can be made of titanium or its usual alloys, or of a titanium alloy with zirconium for example roxolid, because he / she must withstand the efforts due to the insertion of the implant or mastication. The central body can be made, preferably, of zirconium oxide, of roxolid, but also of ordinary titanium, with its alloys, or porous titanium. Because this body does not have mainly the role of resistance, or in other words it is not subjected to special efforts, in its construction we can use low-strength materials such as soft zirconium, which is even cheaper than hard zirconium. The body can also incorporate, inside it, in the central space, specially created for this purpose, or outside it, elements made of a composition known for favoring tissue regeneration.

The biologically active composition, ie including substances that normalize exchanges in the cell membrane and regulate enzymatic balance, accelerate the osseous integration of the implant, must be made of a material capable of emitting resonant electromagnetic waves with biocompatible space or environmental waves adjacent in the infrared and / or radio frequency range. The crystal composition meets this condition, as shown above. It can be made from any of the crystals or substances mentioned above, capable of emitting secondary oscillations at very low frequencies, such as compositions based on opal, topaz, quartz, jade, orthorhombic calcium carbonate, octacalcium phosphate, or any other substance. assets from the point

762

C ^ - 2 O 1 O - O 1 O 1 O - 2 5 -10- 2010 from a biological point of view - already known and currently applied worldwide, or to be developed later. As a particular case, the composition can be achieved by grinding one tooth of that patient, or even another, until the particle size falls in the range of 20 to 150μ, tooth previously extracted for various reasons, because as already mentioned above the natural tooth emits a signal that attracts the progenitor cells in order to regenerate what is destroyed due to microbial activity. Depending on the case, devices can also be made in which powder obtained from animal horns has been incorporated. These powders are indicated to be introduced inside the dental cements and also of the materials for fillings and prosthetic works because they have three advantages at the same time:

- generates biocompatible secondary radiation;

- they will cause the formation of new dentin called secondary dentin;

- bring the coefficient of thermal expansion of different materials close to the coefficient of the natural tooth, thus avoiding fractures.

The composition can be used in powder or pressed form and must be suitable for the problem to be solved in a particular patient, in order to make implant elements for example in the form of granules, filiform, tubular or small bolt, depending on the function. the shape of the inner space of the implant - simple or embedded in a polar polymeric material, easily polymerizable or fusible, of high or low density, as the case may be, ie a material that does not shield the secondary oscillations with low frequency. By embedding it in a polar polymer such as low or high density polyethylene or in another polymer with a better degree of polarization, the composition can also be used to make larger implant elements - which we will hereinafter referred to as dental devices such as healing and / or healing abutments or even temporary prosthetic abutments to be finally replaced with metal abutments made of titanium or, preferably, zirconium oxide or roxolid. It is recommended that these abutments be made by embedding minerals in polymers with higher polarity than polyethylene and higher hardness, such as e.g. acrylate. Also, from acrylic material, in which minerals have been incorporated, root pivots for dental roots, acrylic dental works such as prostheses or fixed works, etc. can be made. Various other types of medical devices used supragingival can also be made, such as splints or rails for immobilizing teeth and implants. In addition, for those who cannot adapt to wearing a gutter, pillows can be made on which they can sleep at night or even various covers. And this is because research has shown that the effect of the composition is manifested at a distance of 15 mm around it (Dr. David Cohen). To these devices

IU ι> 2 010-01010-2 5 -10- 2010 external electrical sources can be attached to reheat them after a certain period of time.

Moreover, although the object of the present invention is limited only to certain problems of the oro-maxillo-facial area, we recommend adopting this method by using specially adapted external devices and to solve similar problems in other fields - cosmetics, orthopedics, rheumatology, etc.

Regarding its incorporation in a polymer, the process is as follows: the active crystals are mixed with polymer granules with high polarity at the specific temperature of the respective polymer after which they are regranulated by breaking the block thus obtained. The new granules are processed to the required shape by hot or cold pressing in the mold. For making gutters, pillows, covers, the respective granules are hot pressed between two or more polar polymer sheets, thus obtaining a sandwich product. The advantage of this technique is that the active minerals do not come into contact with the tissues and thus reduce the risk of side effects.

We draw attention to the fact that, in addition to those mentioned in the patent description Fr 2933610, we come with the specification that a powder obtained from any mineral can be used that can secondary generate low frequency oscillations, resonating with biocompatible electromagnetic waves of space, in infrared or radio frequency range. The accelerating effect of the post-operative recovery of the tissue around the titanium implant inside which mineral powder was placed could also be explained by the effect of secondary infrared emission and in the form of low frequency oscillations in the characteristic spectrum of the powder. minerals thermally excited by the heat of the mouth. It is transmitted to the mineral composition by thermal conduction made by the head and respectively the titanium rod of the implant which is the object of the invention. The composition takes caloric energy (IR) from the surrounding tissue and selectively retransmits it in the form of two types of energy: frequencies. «Rarity and low frequency oscillations that are transmitted very well through the outer zirconium oxide mantle of the implant, the surrounding biological tissue.

The explanation of the role of secondary source in the spectrum of biocompatible radio waves, role generating beneficial biological effect of mineral powder, could be that of easy ionization of mineral powder particles under the influence of thermal vibrations in the characteristic IR spectrum, electromagnetic oscillations resulting from electromagnetic vibrations to which the implant electrons are subjected and also the ionized particles of mineral powder inside, under the action of electromagnetic waves from surrounding sources that have the frequency in the biocompatible spectrum, such as electrotherapy spectrum, for example - in the frequency band of 3-30 MHz or in the decimetric microwave range ^

5 W- 7010

We repeat, it is obvious that any type of composition already known and used at present or discovered in the future can be used as having favorable effects on the success of an implant. These natural or synthetically made minerals, minerals of human origin, minerals of animal origin can be used alone or by mixing them together. However, if the mixture is intended to be included inside an implant, then it will preferably be used as a powder, plain or pressed, to make the effect stronger. Likewise, the composition will also be used in powder form if it is introduced in the space created after the devitalization of a tooth or at the root of a tooth.

As already mentioned, the active substances inserted in the implant will cause more cells to migrate to the implant and, most importantly, they cause the affected cells to recover and preserve the morphotype and phenotype of the cells that reach the implant surface, helping to its good integration into the alveolar bone.

Dr. David Cohen's therapy research (http://newyorkbodyscan.com/mineral-infrared-therapy-theory.html) shows that the cellular mechanism by which it acts consists in regulating the enzymatic balance and regulating exchanges in cell membranes.

The set of medical devices for slowing down tissue resorption according to the invention has the following main advantages:

combines the biological qualities of materials with low machinability but high biocompatibility with those with high machinability and high mechanical strength, each of these materials being positioned in key areas and the combination of them safe; for example, it allows the combination of the so-called grade 5 titanium, for the realization of the self-tapping head with grade 2 titanium, with porous titanium, with elements of zirconium oxide or roxolid at the level of the outer casing. The result is a very good primary stability of the implant due to the self-tapping head combined with the biological qualities of the outer sheath;

the adopted construction also allows the realization of implants with predetermined elasticity by varying the ratio between the mass of titanium elements and the mass of zirconium oxide elements that make up an implant; in this way, depending on the hardness of the part of the bone in which the implant is to be inserted, we will be able to decide the type of implant according to that part;

allows the incorporation or attachment of active substances that promote the recovery of affected cells and accelerate osseointegration;

although it includes ceramic materials, in a relatively large proportion, the implant still allows the realization of any prosthetic works, such as those possible only for metal implants such as threaded works and the parallelization in the laboratory of prosthetic abutments;

5 -10- ZflIiJ hybrid construction of the implant has as main advantage the fact that titanium, having a good thermal conductivity, takes heat from the mouth and transmits it to the mineral composition that generates the two types of secondary oscillations and zirconium oxide has the advantage of a very good their transmissions to the surrounding tissue.

it is possible to change only the prosthetic abutment in case of fractures, implantation accidents, etc., not being obliged to remove the entire implant; also if we have an acute episode of perimplantitis we can change the final abutment with an abutment of minerals incorporated for example in acrylate or other polymer with high polarity, for a fast regeneration;

it is not possible to form electric cells when combining zirconium oxide with titanium; however, some embodiments of an implant in accordance with the present invention are intended to be used in the case of extremely sensitive individuals, since the only titanium element is disposed inside an implant body made entirely of zirconium and the prosthetic abutment. it can also be made only of zirconium oxide; also, if different electromagnetic wave generating devices are used, galvanism cannot occur because the coronary head of the implant is made of zirconium oxide;

any areas of contact between the components are below the average third of the implant, ie where it is no longer necessary to try to treat a possible peri-implant but it is already proven that we need to change the entire implant;

the use of prosthetic and / or healing abutments from a composition adapted to the respective case favors the osseointegration of the implant and the decrease of the chances of the appearance of postoperative dehiscence and periimplantitis. It should be noted that these abutments can be used not only for the implant according to the invention but also for any other type of implant, already existing on the market;

While dental implants are made in factories that have approved working conditions, dental devices that are applied over the implant can be made both in these factories and in dental laboratories resulting in pivots and inlays, crowns and bridges, prosthetic abutments and healing from materials with a high degree of polarity, acceptable physiognomy and strength, etc.

- the incorporation in cements and filling materials ensures, in addition to the secondary emission of regenerative frequencies, the improvement of the thermal expansion coefficient, thus, implicitly, a longer duration of resistance of the prosthetic work.

Further embodiments of the invention are given in connection with FIG. 1 to 57 which represent:

/ ri ^ -2 010-01010-2 5 -10- 2010

- fig. 1, general view, axonometric, of a dental implant, according to the invention, in a first embodiment, having the healing abutment mounted;

- fig. 2, general view, axonometric, with axial section, partial, through the same implant but without healing-healing abutment;

- fig. 3a, b, longitudinal section, according to the plane A-A, through the implant - fig. 3a, and, top view - fig. 3b;

- fig. 4a, b, c, longitudinal section, according to the C-C plane, through the central stem of the implant - fig. 4a, top view - fig. 4b, axonometric view - fig. 4c;

- fig. 5, general view, axonometric, of the self-tapping head;

- fig. 6, longitudinal section through the central mantle, in the variant - threaded on the outside and frustoconical on the inside;

- fig. 7, longitudinal section through an active element, of tubular type, to accelerate the osseointegration;

- fig. 8, longitudinal section through a healing abutment;

- fig. 9 is a general, spatial view of a dental implant, according to the invention, in a second embodiment, with a bayonet-type assembly of the component elements;

FIG. 10, general view 10a, and longitudinal section, axial, 10b, through the implant body of FIG. 9 and 10a, with a view to the central core fixing channels;

- fig. 11, general view of the central core of the implant;

- fig. 12, general view of the osseointegration accelerating element;

FIG. 13, general view, axonometric, with partial section of an implant, according to the invention, in a third embodiment, namely with the fixing of the prosthetic abutment with Morse cone;

FIG. 14, longitudinal section, axial, according to the plane A-A of fig. 16, of an implant, according to the invention, in the third embodiment;

- fig. 15, longitudinal section, axial according to the plane B-B of fig. 16, of an implant, according to the invention, in the third embodiment;

FIG. 16, top view of an implant, according to the invention, in the third embodiment, implant shown in the longitudinal sections of FIG. 14 and 15;

FIG. 17, general view, axonometric, of the sheath / body of the implant, the third variant, shown in fig. 13;

FIG. 18, general view, axonometric, with partial section, of an implant, similar to the one in the third variant, fig. 13, but provided with prosthetic abutment and fixed to the implant by means of an ordinary screw;

FIG. 19, general view, axonometric, of a prosthetic abutment, the screw fixing variant;

5 -10- 2010

ZfT-

- fig. 20 to 23, general sectional view of another implant, according to the invention, in a fourth embodiment, namely with self-tapping head provided with a support rod and the assembly of the abutment to the body of the implant by screw;

- fig. 24 is a variant of the implant shown in Figures 20 to 23 in which the upper head of the implant is provided with a bottom wall separating the seat in which the prosthetic abutment is to be screwed from the seat of the self-tapping head rod;

- fig. 25 to 27, the 5th embodiment of the implant according to the invention in which the upper head is provided with a threaded recess for fixing the abutment and with a rod for fixing it in the jacket / body by means of a pin;

FIG. 28 to 31, another embodiment of the implant of FIG. 25 to 27 at which the joint of the upper head of the implant is fixed to the sheath by suitable gluing or welding;

- fig. 32 to 34, the embodiment of the implant of fig. 1 to 6, in which the fixing on position of the self-tapping head of the rod of the upper head rod of the implant is made by pin;

- fig. 35 to 37, the embodiment of the implant according to the invention in which its body is plugged in its lower part with a stopper in order to more easily introduce the regenerating composition and with an internal hexagon for carrying out its insertion;

- fig. 38 to 41, the embodiment of the implant according to the invention in which its body is plugged in its lower part with a stopper in order to more easily introduce the regenerating composition and with an external hexagon for carrying out its insertion;

- fig. 42 to 47, the embodiment of the implant according to the invention in which its body is provided on the inside with a bush, glued or welded to it, for assembling the prosthetic abutment;

- fig. 48 to 49, the embodiment of the implant according to the invention in which its body is provided on the inside with a bush, glued or welded to it, for assembling the prosthetic abutment and at the lower end with a hexagonal processing in which the self-tapping head is fixed;

- fig. 50 to 54, the embodiment of the implant of FIG. 48 to 49 in which the self-tapping head is also screwed into the inner sleeve, in order to ensure the maintenance of the inner sleeve in position;

- fig. 55 to 57, embodiment of the implant of FIG. 50 to 54 in which the self-tapping head was replaced with a simple head screw to ensure that the inner sleeve remained in position.

c <-2 Ο 1 Ο - Ο 1 Ο 1 Ο - 2 5 ΊΟ- 2010

In order to be able to solve the proposed technical problem, which is very complex, the implant will have to meet the following requirements established by the technical problem; we resume them in more detail:

To allow the combination of the machinability of titanium and its alloys with the biocompatibility of zirconium. This means that the elements of the implant that will undergo mechanical processing such as thread of different shapes and sizes must be made of titanium and the rest of the body to facilitate osseointegration to be made of zirconium oxide. Looking only at this aspect, it is obvious that the ratio of zirconium oxide to titanium with its alloys must be as high as possible. In addition, if the doctor is facing a very delicate situation, namely a patient who is extremely sensitive to the presence of titanium in the implant, he must be able to choose an implant that, although it includes titanium in his body, must still be only inside it and cannot come into contact with the tissues around it.

It should be possible to correlate the elasticity characteristic of the implant with that of the part of the jaw or mandible in which it is to be inserted. This means that the dentist, depending on the specific case he has to solve, must be able to choose a more rigid or elastic implant depending on the place where it is to be inserted.

In order to accelerate the recovery of the tissues affected by the insertion of the implant and implicitly its osseointegration, it must allow the incorporation inside it, or attached to it, of one or more implant elements, made of a composition known and accepted by practitioners. it has a stimulating action on the progenitor cells and produces the restoration of all the affected tissues.

Since the present invention presents the technical solution which is the subject of it in many constructive embodiments, but all obviously having at their base the same inventive concept, in order to preserve the unity of the invention, we consider it necessary to say a few words about the embodiment indicated for one case or another. The first conclusion that can be drawn is related to the consistency or hardness of the bone in which a certain type of implant is to be inserted. Implants with higher elasticity will be used in the posterior area where the bone is soft and elastic, while in the frontal area, where the bone is hard, implants with lower elasticity will be chosen.

The dental implant with increased biocompatibility, according to the invention, is made, in a first variant, presented in figures 1 to 8 in the form of an assembly composed of several parts, each with a well-established role in the actual implantation, in increasing the biocompatibility and in accelerating osseointegration. This first variant includes an upper head with central rod 1, hereinafter referred to more briefly as the central rod which can be made of ordinary titanium alloys - alloys themselves well known and used at the time.

5 -10- 2010 current, for example grade 5 titanium, the most used, or grade 2 titanium. Obviously it can also be made of the new type of titanium-zirconium alloy called roxolid. The central rod, 1 has a multiple role. First, it has the role of taking over both the torsional stresses that occur during the actual implantation and the compression and bending stresses that occur during mastication. Then, as in the present case, a self-tapping head 2 can be arranged at the lower end of the rod (see also fig. 5), made of the same material as it to avoid the formation of an electric battery and at the same time to a durable bonding could be achieved - by any suitable procedure - between the two components 1 and 2. obviously, this solution also allows the combination of grade 5 titanium, recommended for making the self-tapping head, with grade 2 titanium usable in the outer jacket. Head 2 is provided for this purpose with an ι-cutting thread, with one or more beginnings and with ace-cutting teeth. In addition, the titanium construction of a self-tapping head 2, provided with cutting teeth has the advantage that it contributes to increasing the degree of primary stability and will allow the insertion of a ceramic implant in areas with fragile bone such as immediately post-extraction. The third part of the assembly is a central body or, in other words, a central mantle 3, (see also fig. 6) made, preferably, only of zirconium oxide, in order to facilitate the integration of the implant in the mandibular bone or in the jaw. However, it can also be made of porous titanium or titanium-zirconium alloy, roxolid, already mentioned. On the outside of the central mantle 3 we can add various compositions to increase biocompatibility, e.g. proteins or various minerals, a solution known per se. This sheath may have a cylindrical or slightly tapered shape and should preferably be threaded on the outside or at least provided with an embossed pattern to allow it to be anchored inside the dental bone, or it can be smooth. The jacket 3 may surround, at a certain distance, the central rod 1, so that there is or not a small empty space between it and the rod, of ₄ , in which a composition for accelerating the biointegration of the implant can be introduced, in the form of dust. or, as the case may be, the fourth element of the assembly may be introduced, namely a tubular part 4 (see Figs. 2, 3a and 7) or, in other words, an element for accelerating the osseointegration of the implant made of a composition mentioned above, e.g. a composition known per se, based on opal and calcium carbonate, or other substances which have the role of accelerating osseointegration used at present or which will be discovered in the future. For the role of part 4 in accelerating osseointegration, we will also call it active cartridge. It is true that zirconium does not conduct heat but the rod is made of titanium and it has a good thermal conductivity. Therefore, the heat from the mouth will be transmitted through the rod to element 4, which in turn will emit secondary frequencies favorable to the human biofield. when heat reaches our minerals they generate infrared radiation and / or very low frequency oscillations, also biocompatible,

5 -10- 2010 products of lightly ionized mineral particles. The transmission of these secondary radiations through the zirconium mantle is very good, this being the major advantage of zirconium oxide. In fact, this is the basic mechanism for increasing the biointegration of our implant.

It is found, from the above, that we are dealing with a set of parts made - in order to achieve the proposed purpose - from different materials, which entitles us to call it hybrid. After mounting, the obtained assembly is stiffened by a process of gluing or welding the end of the central rod 1 to the front of the drive head 2. the connection can also be made by means of a simple pin, not shown, which penetrates diametrically through both parts. This variant will be presented later in this paper. Obviously, in order to avoid the formation of an electric battery, this pin will have to be made of material identical to parts 1 and 2. We mention here, if necessary, that securing a multi-piece joint with a pin is a very used procedure in the technique. it is practiced in cutting-edge fields of technology, in car construction, in aviation, in the armament industry, etc. That pin must form a tightening fit with the parts it passes through. It is introduced, for example, by pressing or other process appropriate to the case and can only be extracted by applying at least equal force and the opposite direction.

The central rod 1 is provided - see fig. 4 - with a cylindrical, polygonal or slightly frustoconical head bi extended with an elongated portion b ₂ of polygonal shape, for example hexagonal, along which all the other parts are to be mounted. The polygonal shape of the elongated portion b ₂ is necessary, firstly, because the self-tapping head 2 must be driven in rotational motion by rotating the rod and secondly because if both parts - the head 2 and the jacket central 3 - are threaded on the outside, the two threads must be arranged, preferably, in extension of each other, which is made easier by rotating them, by 60 degrees, after the sides of the elongated polygonal portion b ₂ . The other bi end of the rod 1 has, as I said before, the shape of a cylindrical body, slightly frustoconical or even polygonal, of diameter approximately equal to the outer diameter, upper of the mantle 3. Inside it the bi head can be provided with a slot hexagonal, axial, b ₃ continued, also axial, with a relatively short threaded portion b ₄ , because here the prosthetic abutment is to be screwed.

In the hexagonal seat b ₃ of the upper end bi of the central rod 1, a healing / healing abutment 5 can be arranged first - represented in fig. 8 - and then, after scarring, a prosthetic abutment, known in itself, on which the dental crown is to be made. They can be tightened to the desired position by means of a screw, also known solution. The hexagonal seat b ₃ serves both for inserting the implant into

5 -10- 2010 alveolar bone and to be able to mount the prosthetic abutment in the most favorable position in terms of tooth alignment.

Healing / healing abutments can also be made of polymers containing the composition according to the invention to stimulate integration. If the composition is incorporated into an acrylate, or another hard polar polymer, then even a temporary prosthetic abutment can be made from the resulting mixture. As particular variants of realization of this first variant of implant according to the invention we can note that we can make the body bi and with a hexagonal shape on the outside shape that serves both for inserting the implant in the alveolar bone or for mounting a prosthetic abutment provided with a hexagonal seat suitable. At the same time, the jacket 3 can be anchored, against twisting - if its inner diameter is larger than the diameter of the circle in which the polygon of the bi portion of the rod fits. The work is done very easily by various shape details such as hexagonal portions or some wings as shown in fig. 13 and 17 and then in all the variants presented in figures 20 to 34. It is, we believe, obvious that this type of implant allows that, if the dentist deems it necessary - depending on the patient's health, his age, etc. - he chooses an implant with or without the active cartridge 4.

It is also obvious that this type of implant can be made without the inner space of ₄ affected by a composition of accelerating osseointegration, in which case mantle 3 will become slightly more voluminous. However, we specify here that all the variants described here allow the insertion of a composition inside them, only by creating a play between the central rod and the zirconium or other material mantle.

It is also obvious that in a construction similar to this one can give up the self-tapping head 2 case in which the outer jacket can be closed at the bottom and the rod 1 can be secured e.g. also through the pin - see also fig. 13 - and will train the mantle in rotational motion, at implantation, also by means of a polygonal locus, for example hexagonal.

The second implant variant, shown in fig. 9 to 12 show us an implant body 6, tubular, in the shape of a glass, ie open only at the top and closed at the bottom, so that an empty space Ci is created inside it. A central core 7 is inserted in its lower part, which is anchored in the implant body by a simple short twist. For this purpose the tubular body 6 is provided in the upper part with some short channels c ₂ , in the shape of L. The central core 7 is provided with some protrusions c ₃ made in correspondence with the channels c ₂ . It is evident from the drawings that the core 7 is inserted axially into the tubular body 6 and then rotated briefly to anchor it in said body. The assembly of the two components is therefore extremely simple. in the created space Ci is introduced an active pill, cylindrical, 8, made of a composition cx- 2 Ο 1 ο - Ο 1 Ο 1 ο - 2 5 -10- 2010 suitable for that case. The central core 7 is made of titanium or its alloys in terms of implantation and is provided inside with an oval or hexagonal c ₄ processing made in correspondence with the prosthetic abutment used. For the insertion of the implant in the alveolar bone, the tubular body 6 is provided in its extreme, upper part, with a hexagonal processing c ₅ performed on a small portion of its length. However, it is obvious that implantation in the dental bone can also be done using an internal key suitable for c ₄ processing. On the outside, the body 6 is provided with a thread of known shape ₃ . The core of May 7 is provided in its lower part with a thread Ce- It serves to fix the prosthetic abutment by means of a screw that pierces it. If we also make the prosthetic abutment also from zirconium oxide, it is obvious that this type of implant is recommended for people with a very special sensitivity to metals. The tubular body will therefore be made of zirconium oxide or titanium alloys already mentioned above. Outside or not, substances can be added to increase its biocompatibility.

Figures 13 to 17 show the third embodiment of the dental implant according to the invention. This implant also includes a central rod 9 which is inserted into a tubular body 10 plugged at the lower end and open at the upper one where the rod is inserted. Although more rigid at first, the elasticity of this implant model will vary over time due to the play that occurs between the titanium head and the zirconium oxide body. And that's because zirconium will embrace the titanium rod. This adjustment, over time, of the elasticity of the implant is determined by the change in bone structure. We can say that the implant adapts to changes in bone elasticity. Due to osteoporosis or even physiological aging of the bone, over time it becomes spongy. Over time, as the elasticity of the implant increases, it will adapt to the new situation. Moreover, this advantage - very important - is found in most implants that are the subject of the invention except those that are made entirely of zirconium oxide. Total zirconium oxide implants are recommended to be used in the anterior area of the jaws combining the aesthetic advantage of achieving the cervical area of the zirconium oxide implant while maintaining high rigidity, synchronous with changes over time in the bones of the anterior area of the jaws. The elasticity of the implant can vary in time and depending on the metal from which the pin is made as well as its position along the rod, so implicitly depending on its length. A pin made of a more elastic metal can allow a higher elasticity of the implant. However, the embodiment allows the assembly of the two elements to be carried out by means of a fixing pin 11. The rod 9 can be made in the manner known from variant 1. In other words, it is provided with an upper head di in which the boit will be inserted. prosthetic and with a polygonal portion d ₂ , for example hexagonal, as in the first variant. However, for example, the upper head is provided with a hexagonal machining d ₃ which serves both to insert

5 -10- 20W of the implant in the alveolar bone as well as when fixing the prosthetic abutment on the correct position. It also includes a d ₄ machining for assembly with a prosthetic abutment by the con morse process. It is obvious that nothing prevents us from processing for assembly, with the prosthetic abutment, through the thread, exactly as in the first variant, just as it is equally obvious that the body b of the rod in the first variant can be machined for assembly with cone. walruses. What appears new, in this case, at the rod, is the fact that, at its joint with the tubular body 10, the polygonal extension d ₂ is also provided with two lateral fins d ₅ , arranged diametrically. These fins enter two recesses d ₆ made, in correspondence, in the body 10 shown in fig.

17. Obviously, the assembly of the rod 9 with the tubular body 10 will be firmer. The body 10 is provided, as expected, with a closed axial processing d ₇ in which the pill with active substance already mentioned several times so far will be introduced. We have already mentioned that the assembly of the central rod 9 with the tubular body is done with the help of a fixing pin 11. in this sense through the two parts 9 and 10 a hole d ₈ will be given perpendicular to the longitudinal axis of the implant or lateral, perpendicular to the plane. axis but median of the two wings. It should also be added here that the elasticity of the rod also depends on the degree of alloying of the titanium. For example, grade 5 titanium is stiffer than grade 2 titanium.

Due to the existence of the two side fins d _{5 it} is obvious that it is no longer necessary for the extension d ₂ of the rod to be polygonal. It can also be circular because the two fins take over the turning moment and the pin has only the role of positioning, stiffening and securing the assembly. It is up to the manufacturer whether or not to make the rod 9 polygonal, in a section perpendicular to its axis of rotation, or not, for example, round. As already mentioned, on the outside the two elements 9 and 10 of the implant can be provided with a thread d ₉ . As execution materials, we believe that it is already obvious that the rod 9 can be made of titanium with its alloys and the tubular body 10 can be made of zirconium oxide, porous titanium or titanium alloys with zirconium. Obviously, in this case too we can take measures to increase the biocompatibility of the tubular body by depositing on its outside, through the already known process, growth proteins, minerals or other biological stimulants of integration. Figures 18 and 19 show a concrete example of assembling a prosthetic abutment with the implant itself. The explanations given in Figure 18 are, we hope, quite enlightening. The system for fixing the prosthetic abutment was chosen by means of a tight elastic bush by means of a screw that passes right inside the prosthetic abutment provided with a longitudinal channel. Obviously, the same screw and the same abutment shape will be used if the inner core / central rod are provided with an internal thread (b ₄ , c ₆ ).

(A- L ^J

5 W- 20: 0

Of the three variants presented so far, only the first variant has an implant provided with a leading head 2. We now give another embodiment shown in Figures 20 to 24. Compared to the first variant, things are slightly reversed here. The implant is made of a top, tubular head, 12 made of titanium or titanium with its alloys, or roxolid, an intermediate tubular jacket 13, made of zirconium or porous titanium but also of zirconium with its alloys, a self-tapping head 14 an assembly pin 15, and if necessary, an active pellet 16 can be inserted inside the tubular jacket 13, represented only in fig. 21. We make here the important clarification, in order to prevent any misunderstanding that in figure 20 the mantle 13 is fixed directly on the rod. This is because the dentist considers that for a certain patient it is not necessary to take an additional measure to stimulate regeneration. In the new variant, the self-tapping head 14 is provided with a polygonal-shaped tail - eg hexagonal - in section. Being provided with a support tail, the self-tapping head 14 will be easier and cheaper to make because we will no longer need to create auxiliary devices to attach it for processing. The assembly of the tubular upper head 12 with the self-tapping head 14 is made with a fixing pin 15. in this sense the head 12 is provided at its lower part, starting from the end of the inner thread for fixing the prosthetic abutment, with a polygonal hole, e ₂ made in correspondence with the dimensions of its rod of the self-tapping head 14.

in figure 22 we give another embodiment of the tubular head 12 and of the jacket 13. We mentioned it a little earlier, when we presented figure 17, but in an inverted variant, fig. 13, namely when the upper head was provided with a rod. The head 12 is made here (fig. 22) with two lateral extensions, arranged radially e ₂ which enter into two lateral recesses e ₄ practiced in the jacket 13. in this case, the twisting of the mantle 13 around the tail e ₁ of the head 14 in when an active pill is placed between the jacket and the tail 16.

Figures 20 and 21 clearly show that the distance between the end part of the inner thread of the tubular head 12 and the end head of its rod of the self-tapping head 14 may be smaller or larger depending on their length so that a gap can be created between them. space between which an active composition of any type can be introduced. Obviously, this composition can be changed during the healing of the place where the implant is inserted. However, if you do not want to create this space then, instead, a ββ separator wall can be made as shown in Figure 24.

Many of the changes to this implant are based on the experience and phenomena observed by practitioners in their current work.

Thus, in the case of peri-implant infection, it has been shown that, by different methods, we can sterilize the area affected by the infection provided that in this part of the

Ο 1 Ο - Ο 1 Ο 1 Ο - 2 5 -10- 2010 implant there is no connection between two components. It has also been shown that in the case of an implant in which the periimplantitis has fallen below its upper third, the infection can no longer be treated and it is recommended to change the implant. For this reason, as can be seen, the implant according to the present invention has no connections in its upper third. in addition, this fact gives it a special mechanical resistance.

After implant insertion, periimplant healing goes through several well-known stages in terms of chronology and physiology. In order to act synergistically with the physiology, the dentist can introduce in the space made inside the implant body substances that will generate desired physical signals that will be transmitted through the thickness of the implant to the peri-implant bone. The dentist can induce these signals in the period between the insertion of the implant and the application of the final prosthetic abutment and by applying scarring / healing abutments and a temporary prosthetic abutment containing the desired substances incorporated in the plastic. After the integration period, the final prosthetic abutment must be mounted in the implant, but following this abutment (caught by any attachment system) we will leave a space where the dentist can apply and remove the desired substances to emit the necessary signal. In parallel with these substances that the dentist can decide and change there are already immobilized from the construction of the implant substances that continuously generate signals. The coexistence of the signals permanently emitted by the incorporated substances with the signals emitted for certain periods of time by the substances introduced at the doctor's decision will allow an individualized response depending on the patient's reactivity and the risk of peri-implantitis.

The substance that will be inserted into the implant and remain there may be, for example, calcium carbonate which is known to stimulate bone formation. The substance in the cartridge / interchangeable element will be a composition that includes opal and carbonate to be incorporated into polar plastic. We specify that other minerals mentioned in this patent can be mixed to obtain the ideal formula. This interchangeable cartridge will be inserted for periods of 1-6 months if we detect peri-implantitis to tighten the peri-implant ring and stop the aggravation of the peri-implant. Their introduction in order to prevent the appearance of peri-implantitis is encouraged because a much tighter periimplant ring will be formed which will delay the appearance of peri-implantitis. The same composition is used to achieve the healing / healing abutment that is applied immediately after the implant is inserted. The only difference between the two cases consists only in the fact that when making the cartridge / interchangeable element, low density polymers will be used to make healing / healing abutments, high density polymers will be used because their resistance must be higher although they they do not serve for mastication. However, repeated passage of the food bowl over them can result in their destruction. From c — 1 O O - - ‘” 2 5 -10- 20W on a case-by-case basis, depending on the space available inside the implant, opal powder and / or calcium carbonate can be introduced without being embedded in a polymer.

Since the present invention presents the technical solution which is the subject of it in many constructive embodiments, but all obviously having at their base the same inventive concept, in order to preserve the unity of the invention, we consider it necessary to say a few words about the embodiment indicated for one case or another. The first conclusion that can be drawn is related to the consistency or hardness of the bone in which a certain type of implant is to be inserted. Implants with higher elasticity will be used in the posterior area where the bone is soft and elastic, while in the frontal area, where the bone is hard, implants with lower elasticity will be chosen.

In order to control the elasticity of the assembly and its correlation with the local rigidity of the bone, a variant with zero junctions, a junction or two junctions will be adopted in its construction and the assembly of its elements will be of the left-right double nut type, through thread, pin , bayonet type, nut and spring type, by Morse cone, by laser welding and / or glued assembly with biocompatible adhesives. The principle behind this adaptation of implant elasticity following bone elasticity is explained by the fact that zirconium oxide is harder and will abrade from titanium.

We have presented in more detail the variants so far, which allows us to present only the main elements of differentiation in the following variants.

Fig. 25 to 27, shows the 5th embodiment of the implant according to the invention in which the upper head is provided with a threaded recess for fixing the abutment and with a rod for fixing it in the jacket / body by means of a pin. The stem can also be polygonal in which case you can give up the wings e ₃ . However, we recommend making the two diametrical fins because this can strengthen the inner thread b ₄ . This solution also has the advantage of creating a larger interior space and the fact that the entire body of the implant can be made of zirconium.

Fig. 28 to 31 shows another embodiment of the implant of FIG. 25 to 27 at which the joint of the upper head of the implant is fixed to the sheath by suitable gluing or welding. The twisting of the implant is based only on the e ₃ fins that enter the e ₄ recesses. In other words, if an adhesive is available that is biocompatible with the human body, the head can be joined to the jacket by gluing. Likewise, they can be joined by any welding process that does not cause biological incompatibilities. It is obvious that in this way an even larger interior space will be created. If necessary, you can give up the cover with ₆ threaded bottoms.

Fig. 32 to 34, shows another embodiment of the implant of FIG. 1 to 6, in which the positioning of the self-tapping attachment head 2 of the rod b ₃ of the upper head of the implant

Gl _ό -2 1 ': - î' 2 1 Ο - 2 5 -11) - 21110 is made by the same pin 15. The fins a have also been preserved here because, as already mentioned, the threaded hole b ₄ will be stronger.

Fjg. 35 to 37, shows a new embodiment of the implant according to the invention, namely one in which the body of 16 is made entirely of the same material, for example titanium or roxolid alloy. At the same time, this body is plugged in its lower part with a stopper 17, in order to introduce the regenerating composition more easily and is provided with an inner hexagon b3 for its insertion in the dental bone and with thread b ₄ for fixing the prosthetic abutment. Although we do not think it is necessary, we repeat that this body is also provided on the outside with an embossed design a ^. This variant has another advantage, namely the fact that the implant can be easily made, both inside and outside only by mechanical processing.

Fig. 38 to 41, shows an embodiment of the anterior implant, fig. 35 to 37, according to the invention, in which the body of 16 'is plugged in its lower part with the same plug 17 in order to introduce more easily the regenerating composition but is provided with an outer hexagon g for carrying out its insertion. In our opinion, the advantage of this variant would be that it will be able to increase even more the empty inner volume f. At the same time, the upper end will have a smaller diameter so that a suitable prosthetic abutment can be easily created. It is obvious that the prosthetic abutment will be sufficient to cover only one side of the outer hexagon.

Fig. 42 to 47, shows a favorite embodiment of the implant according to the invention that the body of 18 is provided on the inside with a sleeve 19 threaded on the inside but hexagonal on the outside - in other words it is identical to a simple hexagon nut - glued or welded by it , for assembling the prosthetic abutment. The bushing 19 being completely arranged inside the body 18, the biocompatibility condition of the soldering solution is no longer so severe. On the other hand, it is obvious that this implant body can be made entirely of zirconium because it does not undergo any complex technological processing, such as thread. It should be noted that it can also be provided with an inner plug through which it can be filled with active substance or, possibly, welding the bushing to the implant body. The arrangement of the hexagonal bushing inside the implant body will be done by providing in its upper part a hexagonal processing h made in accordance with the dimensions of the hexagonal bushing.

Fig. 48 to 49, shows a variant partially similar to the previous one for making an implant according to the invention in which the body of 18 'is also provided inside with an identical bush 19, glued or welded by it, for assembling the prosthetic abutment, but at the lower end it is provided with another hexagonal processing h'in in which it is fixed, also by ii> ~ 2? ¹ 3 -? '3'2- ^J 2 5 ^: 0 · 2010 adequate soldering or welding, a self-tapping head 14', similar to the head 14, with the only difference that it has a tail or rod / much shorter.

Fjg. 50 to 54 also shows a preferred embodiment of the previous implants, from fig. 42 to 49 in which an 18 ”body is similar to the previous two but made even simpler, ie without hexagonal processing h’. in this case, a 14 ”self-tapping head is screwed into the inner sleeve to ensure that the inner sleeve is held in place. for this purpose the leading head is provided with a threaded tail in accordance with the thread of the sleeve 19. The solution is very simple and recommended by us because we do not have to do any additional work to keep the inner sleeve in position. All implants, from 48 to 54, also have the advantage that being provided with a self-tapping head ensures a very good primary stability, even if they are ceramic.

Fig. 55 to 57, embodiment of the implant of FIG. 50 to 54 in which the self-tapping head was replaced with a simple head screw 20 to ensure that the inner sleeve 19 was held in position.

And now a few extra words about each component of the set according to the invention. With reference to the dental implant itself, the first and most important device in the set, it is made in hybrid construction - ie from several materials with different strength, biocompatibility and physico-chemical qualities - but specially chosen so that by combining them have obtained an implant capable of generating technical effects with a new biological character and is called by us, an implant with high biocompatibility and controlled elasticity and self-adaptable over time because these are its two main biological characteristics.

Although similar or even identical in shape, however, the implant embodiments may differ from each other both in terms of the constructive solution, chosen for one or more components of their composition, but also in terms of materials from which are made or which can be added to these components. This fact can give the implant different and totally unexpected physical and biological qualities, so that it becomes possible to obtain a product that responds better to the concrete situation that the dentist may encounter in a certain patient. Due to the combination of materials possible to use in its realization, which is why we, as seen above, we also called it implant in hybrid construction, it has an increased tissue integrability but also a controlled elasticity adapted to the elasticity of the jaw portion. or the mandible in which it is to be implanted.

At the same time, the invention relates to a composition, which can be used both inside the implant and outside it in order to restore the tissues, nerves and bone structure affected by the insertion of the implant. It is used in the form of elements of

Λ-2 5 1 PC '3 = - 2 5 -IC- 2C1U implant and dental devices of different shapes and sizes, interchangeable, depending on the specific situation existing in each patient at the date of implantation or depending on the situation that may occur later to that patient. This fact obviously leads to the acceleration of the osseointegration of the implant from a biological point of view, which is why we also called it regenerative and with active osteointegration, because it also contributes to the regeneration of the tissues and bone structure affected by the operation. Its special construction allows the integration of simple elements made of the composition ₍ »? Ntioned but also the addition to its exterior of dental devices also made of this composition, devices that also have the same role of slowing down the resorption of tissues affected by Therefore, the implant according to the invention will have new features in the variant according to the invention, namely it is with high biocompatibility, controlled and self-adaptable elasticity and also slows down the subsequent resorption of tissues.

The composition according to the invention includes substances known and used as biologically active, ie substances which normalize exchanges in the cell membrane and regulate the enzymatic balance, namely, natural or synthetic crystals of opal, topaz, jade, olivine, carbonate. orthorhombic calcium, octacalcium phosphate, and, where appropriate, crushed natural salt crystals, including powder obtained from teeth, horns, human or animal bones. All of these can be used alone, as such, or mixed with each other and can also be used as such or embedded in a polar polymer. It is recommended that this polymer has a polarization greater than or at least equal to that of polyethylene. From this composition are made simple elements in the form of powder or filiform or small bumps that have the shape of the implant cavity as well as various devices with a prophylactic and curative role that can be attached to the implant, can be worn in the mouth or are for external use.

when arranged inside the teeth or implants these elements may be in the form of dust or the shape of the gap made inside the tooth or implant.

From the composition embedded in a polar polymer are made, either in industrial conditions or in the dental laboratory, scarring / healing or prosthetic abutments, dental prostheses, fixed works, obtained either by grinding teeth or by coating teeth on all faces or only on some faces, orthodontic appliances, root pivots, immobilization rails or gutters as well as in the form of pillows or covers provided with thermostatic heating systems up to a temperature bearable by the human body.

The process for obtaining medical devices such as healing / healing abutments and prosthetic abutments, including splints, cushions and covers, consists in that the active crystals are mixed with polymer granules with high polarity at temperature.

5 -10- 2010 specific to the respective polymer, after which it is regranulated by breaking the block thus obtained. To obtain abutments for the implant, the granules will be pressed into the mold, while to obtain gutters, cushions and covers, the granules obtained are hot pressed between two or more polar polymer sheets, depending on the required rigidity, thus obtaining a product. sandwich type from which the final product customized to each patient can be obtained.

Said devices will be made of materials that emit secondary oscillations in the frequency range of 7 Hz if they are intended for bone regeneration, 10 Hz if they are intended for ligament regeneration, 15, 20 and 72 Hz if they are intended for the formation of new capillaries and 2 Hz, 25 Hz and 50 Hz if intended for nerve regeneration, or 33.3 Hz if the resonant frequency of calcium is intended primarily for tissue regeneration in tissues.

Claims (14)

Set of medical elements and devices for slowing down tissue resorption. 1. Set of medical elements and devices for slowing tissue resorption in people who want to maintain their teeth either natural or rehabilitated implant-prosthetic, characterized in that it includes a hybrid dental implant, ie made of several materials with different mechanical characteristics to be able to control its elasticity and biocompatibility and to be able to be realized in several constructive variants, depending on the local elasticity of the patient's bone, implant provided with an empty space inside it to be able to insert a composition that includes crystalline minerals for be able to emit secondary oscillations with constant frequency, known and used as biologically active by normalizing exchanges at the cell membrane and regulating the enzymatic balance, namely, crystalline minerals, natural or synthetic opal, topaz , jade, olivine, ortho calcium carbonate mbic, octacalcium phosphate and, where appropriate, crushed natural salt crystals, including powder obtained from teeth, horns, human or animal bones, all used alone, as simple elements, or mixed with each other and used as such or mixed in dental cements, augmentation materials and filling materials or as medical devices in which case the composition will be embedded in a polar polymer preferably having a polarization greater than or at least equal to that of polyethylene from which unitary assemblies made of several landmarks and distinct elements that include the composition, a support for it and possibly a heating system. High biocompatibility dental implant according to claim 1, characterized in that, in order to provide a modulus of elasticity adapted to the elasticity of the mandible or jaw portion into which it is to be integrated, it includes an upper head provided with a central rod or, where appropriate, a central core, of variable length, to obtain a variable elasticity compatible with the elasticity of the place where the implant is to be inserted, the rod being provided, respectively the central core being provided, for this purpose, with a threaded recess or a cone. Morse in which the prosthetic abutment can be fixed, said rod or the central core being fixed inside a central body made of a material with high biocompatibility, the body being provided with an axial space created by the difference between the body volume and the volume of the rod or core to which the prosthetic abutment is fixed; at its lower end, after the central body, the rod can also be provided, with a self-tapping head provided, in turn, with one or more beginnings. High biocompatibility dental implant according to claims 1 and 2, characterized in that, in order to ensure increased biocompatibility and controlled rigidity, the central rod / central core and the self-tapping head are made of titanium a- 2 oic - en <c - 2 5 -10- 2D1C or its ordinary alloys, or of roxolid, and the central body will be made, preferably, of zirconium oxide, of roxolid, as well as of ordinary titanium, with its alloys, or porous titanium or possibly from another biocompatible but low strength material such as soft zirconium oxide. High biocompatibility dental implant according to Claims 1, 2 and 3, characterized in that the space for arranging the compositions is created between the volume of the central rod or the central core, which can be reduced to a single bush and the inner volume of its body. Composition according to Claim 1, characterized in that, embedded in a polar polymer, it is made either under industrial conditions or in the dental laboratory in the form of scarring / healing or prosthetic abutments, dental prostheses, fixed works, made either by grinding either by applying over existing crowns, on all sides or only on some of their faces, root pivots, immobilization rails or gutters as well as in the form of pillows or covers provided, on a case-by-case basis, with thermostatic heating systems up to a temperature bearable by the human body. Dental implant according to claim 1, characterized in that, in order to control and self-adapt over time the elasticity of the assembly with the local rigidity of the bone in its construction, a variant with zero junctions, one junction or two junctions is adopted and the assembly of its elements is will make left-right double nut type, threaded, pin, bayonet type, nut and spring type, Morse taper, laser welding and / or solder assembly with biocompatible adhesives. Devices according to claims 1 to 5, characterized in that, on a case-by-case basis, they are made of materials which emit secondary oscillations in the frequency range of 7 Hz if they are intended for bone regeneration, 10 Hz if they are intended for ligament regeneration, 15, 20 and 72 Hz if they are intended for the formation of new capillaries and 2 Hz, 25 Hz and 50 Hz if they are intended for nerve regeneration, or 33.3 Hz if the resonant frequency of calcium if they are intended mainly for the regeneration of calcium in tissues. Process for obtaining medical devices according to Claims 1 and 7, such as healing / healing abutments and prosthetic abutments, including splints, cushions and covers characterized in that the active crystals are mixed with high-polarity polymer granules melting, specific to the respective polymer, after which it is granulated by breaking the block thus obtained; after which, in order to obtain abutments for the implant, the granules, in the molten state, will be pressed into the mold, while for obtaining gutters, cushions and covers, either the method described above will be used or the obtained granules will be hot pressed between two or more many polar polymer sheets, depending on the required rigidity (V- 2 sandwich 1 0 - 0 1 0 1 Ο - 2 5 -10- 2010, thus obtaining a sandwich product from which the final product customized to each patient can be obtained. Elements according to claim 1, characterized in that, when arranged inside the teeth or implants, they can be in the form of dust or the shape of the cavity made inside the tooth or implant. Devices according to claims 1 and 7, characterized in that if they are used supragingival they will be made in the form of immobilization rails for teeth and implants, splints of high polarity materials, healing and / or scarring abutments and abutments temporary prosthetics, orthodontic appliances, prosthetic works with all faces of the teeth covered or removing some faces, which can be changed depending on the emitted frequency correlated with the pathology. 11. Devices according to rev. 7, characterized in that they can also be made in the form of gutters, dental work done without grinding teeth, and even bed pillows or covers for different parts of the body, which can be filled with active crystals provided with thermostatic systems. heating that can ensure a constant temperature bearable by the human body. 12. Use of zirconium oxide and its alloys as a transmitter of low frequency secondary oscillations, resonating with the human biofield. Composition according to the preceding claims, characterized in that it can include any other mineral with a regular crystalline structure capable of secondarily emitting a constant frequency compatible with the human biofield. Use of the elements and devices according to claims 1 to 13 for slowing down the resorption of tissues and thus speeding up their healing.