RO120381B1 - Moisturizing day cream - Google Patents

Abstract

The invention relates to a moisturizing day cream comprising 3...6% Aloe vera gel, 0.02...0.04% ascorbyl palmitate, 0.03...0.06% Carbopol 940 (wool fat alcoholic derivative), 0.03...0.06% diethylaminoethanol, 2...4% avocado oil, 2...4.5% cetyl alcohol, 0.5...1% buckthorn oil, 1.5...2.5% glyceryl monostearate, 1...2% phytocollagen, 1...1.5% Amerchol CAB (acryl polymer), 2...2.8% Arlacel 60 (anhydrosorbitol stearate), 1...2% Tween 60 (polyoxyethylenesorbitan monostearate), 2...4% almond oil, 1...2.5% isopropylmyristate, 1...3% methylsilanol manuronate, 1...2% propylene glycol, 0.2...1% wheat germs oil, 0.2...0.5% tocopheryl acetate, 0.1...0.2% rosemary oil and distilled water for the remainder up to 100% by weight.

Description

The present invention relates to a moisturizing cream with protective action of the epidermis, throughout the day.

Free radicals are substances with biological aggression due to free electrons, which can cause chain reactions, leading to alteration of cellular structures, causing the appearance of so-called oxidative stress.

The hydroxyl radical or the superoxide anion, in the presence of a transition metal, such as iron, which is the most widespread, is highly reactive, creating certain biological substrates a state of toxicity. In general, this reaction is under the control of an enzymatic system of the human body, namely under the control of the enzyme superoxide dismutase. If the enzymatic system is degraded, oxidative reactions accelerate, and hydrogen peroxide reacts with reduced iron (Fe ²⁺ ), producing the most toxic free radicals, namely the hydroxyl radical.

O ₂ + Fe ³⁺ - O ₂ + Fe ²⁺

Fe ²⁺ + H ₂ O ₂ - Fe ³⁺ + OH + OH '

Exposure of the skin to ionizing radiation, UV, atmospheric pollution, favors the formation of free radicals, which can cause morphological or histological alterations, in the tissues, which attack the main cellular constituents: lipids (with the effect of breaking the cell membranes), proteins (with breaking effect of SS bridges, crosslinking, alterations of collagen fibers), DNA-deoxyribonucleic acid (with irreversible amino acid chain splits and possible mutagenic effects).

Under the influence of free radicals, the cell membrane loses its functional capacity, both at the cutaneous level, but also in other structures, such as vessel walls, parenchyma, cellular elements of the nervous system, with the appearance of skin wrinkles and ptosis, sclerosis of the vessel walls, immunological diseases (such as Parkinsoh or Alzheimer's disease, etc.).

At the skin level, the collagenic and elastic fibers of the dermis are touched and degraded and the elasticity of the fundamental substance is lost, the result being the appearance of wrinkles, the skin becoming flabby. Lipids undergo a process of peroxidation, and the proteins are concatenated, become harsh, insoluble, lose their elasticity, generally, metal-dependent enzymes (catalase, peroxidase, dismutase, etc.) destroy the free radicals they come into contact with. But if superficial defense reactions are not effective, exogenous intervention is required, with antioxidant substances (vitamins A, C, B, beta-carotene), glucose, organic silicon derivatives, and GEROVITAL H3, which are involved in maintaining enzymatic functionality. .

There are known cosmetic products in the form of creams, which have in their composition various active principles with antioxidant effects, such as vitamin A, flavones, phytosterols (RO 98522, 77101, 97206).

Also known are creams whose composition is active ingredient, a gelatin-glycine-zinc vitaminized biocomplex (RO 87352) or vitamin A associated with amniotic fluid (RO 63700).

These cosmetic products have the disadvantages of insufficient antioxidant, free antiradical action. Known products cannot replace the activity of degraded enzymes, which normally control oxidative processes.

The problem that the invention solves is that by combining the substances in new reports, the bioavailability of the cream increases.

Day moisturizer, according to the invention, contains: 3 ... 6% A / oe vera gel, 0.02 ... 0.04% palmitate ascorbate, 0.03 ... 0.06% Carbopol 940 (derivative lanolin (alcohol), 0.03 ... 0.06% diethylaminoethanol, 2 ... 4% avocado oil, 2 ... 4.5% cetyl alcohol, 0.5 ... 1% quinine oil, 1.5 ... 2.5% glyceryl monostearate, 1 ... 2% phytocolagen, 1 ... 1.5% Amerchol CAB (acrylic polymer), 2 ... 2.8% Arlacel 60 (anhydrosorbitol stearate) ), 1 ... 2% Tween 60 (monostearate

RO 120381 Β1 of polyoxyethylsorbentane), 2 ... 4% almond oil, 1 ... 2.5% isopropyl myristate, 1 ... 3% methylsilanol 1 manuronate, 1 ... 2% propylene glycol, 0.2 ... 1% wheat germ oil, 0.2 ... 0.5% tocopherylacetate,

0.1 ... 0.2% rosemary oil and distilled water up to 100% by weight.3

The advantages of moisturizing cream according to the invention are the following:

- it strengthens the natural defense of the skin by being a cofactor of the enzymatic activity;

- is a moisturizing product, throughout the day; 7

- it is a membrane stabilizer, because it opposes the lipid peroxidation of the unsaturated fats in the cell membranes, participating in the lipid reorganization of the cell membranes9;

- contributes to the restructuring of the elastic substrate by exogenous protein intake and 11 silicon derivatives;

- its association in the systematic cosmetic treatment in the cabinet, namely as a method of 13 maintenance, ensures a visible effect on the skin, invigorating its tone, by maintaining the elasticity of the conjunctive components. 15

An example of the invention is given below.

The composition of the cream according to the invention is as follows: 4 g Aloe vera gel, 0.2 g 17 palmitate ascorbable, 0.04 g lanolin alcoholic derivative, 0.03 g diethylaminoethanol, 3 g avocado oil, 3 g cetyl alcohol, 0.5 g sea buckthorn oil, 2 g glyceryl monostearate, 2 g phytocolagen, 1 g 19 acrylic polymer, 2 g anhydrosorbitol stearate, 1 g polyoxyethylensorbitan monostearate, 4 g almond oil, 2 g isopropyl myristate, 2 g methylsilanol manuronate, 2 g of propylene glycol, 0.5 g of wheat germ oil, 0.5 g of tocopheryl acetate, 0.2 g of rosemary oil and distilled water up to 100% by weight. 2. 3

To the composition according to the invention, a preservative selected from propyl, methyl paraben, imidazolidinyl urea or parahydroxyoxycinnamic acid extracted from Aloe vera (0.1 ... 1% by weight 25) is added.

The process of preparing the cream follows the known steps of preparing the 27 fat phase, separated from the aqueous phase of the ingredients, mixing them at 75'C under vacuum and after cooling the mixture to 40 ° C, add in the oil of sea buckthorn, germ oil of wheat, 29 phytocolagen and tocopheryl acetate.

Moisturizing cream is a protective of the epidermis during the day, while being a good substrate for makeup. It has a quick moisturizing action, is an antioxidant and a toner with visible effects on the face. 33

Claims (2)

Day moisturizer, characterized in that it has in the composition 3 ... 6% gel 37 Aloe vera, 0.02 ... 0.04% palmitate ascorbable, 0.03 ... 0.06% alcohol derivative lanolin, 0.03 ... 0.06% diethylaminoethanol, 2 ... 4% avocado oil, 2 ... 4.5% cetyl alcohol, 0.5 ... 1% 39 sea buckthorn oil, 1, 5 ... 2.5% glyceryl monostearate, 1 ... 2% phytocolagen, 1 ... 1.5% acrylic polymer, 2 ... 2.8% anhydrosorbitol stearate, 1 ... 2% polyoxyethylenesorbitan monostearate, 2 ... 4% almond oil 41, 1 ... 2.5% isopropyl myristate, 1..3% methylsilanol manuronate , 1 ... 2% propylene glycol, 0.2 ... 1% wheat germ oil, 0.2 ... 0.5% tocopherylacetate, 0.1 ... 0.2% rosemary oil and 43 distilled water up to 100% by weight.