PT93877A - PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MEDICINES, FOR EXAMPLE BETA-LACTAMIC ANTIBIOTICS - Google Patents

PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MEDICINES, FOR EXAMPLE BETA-LACTAMIC ANTIBIOTICS

Info

Publication number
PT93877A
PT93877A PT93877A PT9387790A PT93877A PT 93877 A PT93877 A PT 93877A PT 93877 A PT93877 A PT 93877A PT 9387790 A PT9387790 A PT 9387790A PT 93877 A PT93877 A PT 93877A
Authority
PT
Portugal
Prior art keywords
medicines
preparation
pharmaceutical compositions
oral administration
example beta
Prior art date
Application number
PT93877A
Other languages
Portuguese (pt)
Other versions
PT93877B (en
Inventor
David Roy Merrifield
Paul Laurence Carter
Ian James Bolt
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT93877A publication Critical patent/PT93877A/en
Publication of PT93877B publication Critical patent/PT93877B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent

Abstract

A chewable tablet comprises a medicament dispersed in a chewable base, such as mannitol, together with an effervescent couple, such as citric acid - sodium bicarbonate. The combination of effervescence and chewability with optional flavourings improves the taste characteristics of the medicament in oral adminstration. A disintegrant such as microcrystalline cellulose may be added to give the patient the option of dispersing the tablet in water.
PT93877A 1989-04-28 1990-04-26 PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MEDICINES, FOR EXAMPLE BETA-LACTAMIC ANTIBIOTICS PT93877B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898909793A GB8909793D0 (en) 1989-04-28 1989-04-28 Pharmaceutical formulation

Publications (2)

Publication Number Publication Date
PT93877A true PT93877A (en) 1990-11-20
PT93877B PT93877B (en) 1996-09-30

Family

ID=10655920

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93877A PT93877B (en) 1989-04-28 1990-04-26 PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MEDICINES, FOR EXAMPLE BETA-LACTAMIC ANTIBIOTICS

Country Status (17)

Country Link
US (2) US5225197A (en)
EP (1) EP0396335B1 (en)
JP (1) JP2992761B2 (en)
KR (1) KR0167554B1 (en)
AT (1) ATE101034T1 (en)
AU (1) AU627298B2 (en)
CA (1) CA2015536C (en)
CY (1) CY1957A (en)
DE (1) DE69006385T2 (en)
DK (1) DK0396335T3 (en)
ES (1) ES2062353T3 (en)
GB (1) GB8909793D0 (en)
HK (1) HK1004522A1 (en)
IE (1) IE63806B1 (en)
NZ (1) NZ233441A (en)
PT (1) PT93877B (en)
ZA (1) ZA903181B (en)

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Also Published As

Publication number Publication date
IE901489L (en) 1990-10-28
US5225197A (en) 1993-07-06
DE69006385D1 (en) 1994-03-17
AU627298B2 (en) 1992-08-20
KR0167554B1 (en) 1999-01-15
JPH02295919A (en) 1990-12-06
US5962022A (en) 1999-10-05
CY1957A (en) 1990-04-26
DK0396335T3 (en) 1994-03-07
AU5391490A (en) 1990-11-01
HK1004522A1 (en) 1998-11-27
ATE101034T1 (en) 1994-02-15
CA2015536C (en) 1999-08-24
CA2015536A1 (en) 1990-10-28
EP0396335B1 (en) 1994-02-02
GB8909793D0 (en) 1989-06-14
JP2992761B2 (en) 1999-12-20
ZA903181B (en) 1991-06-26
DE69006385T2 (en) 1994-05-19
NZ233441A (en) 1992-03-26
ES2062353T3 (en) 1994-12-16
EP0396335A1 (en) 1990-11-07
IE63806B1 (en) 1995-06-14
PT93877B (en) 1996-09-30
KR900015716A (en) 1990-11-10

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Legal Events

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FG3A Patent granted, date of granting

Effective date: 19960628

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20061228