PT91410A - Process for the identification and use of biosynthetic genes or regulating genes for the improved production of secondary metabolites - Google Patents

Process for the identification and use of biosynthetic genes or regulating genes for the improved production of secondary metabolites

Info

Publication number
PT91410A
PT91410A PT9141089A PT9141089A PT91410A PT 91410 A PT91410 A PT 91410A PT 9141089 A PT9141089 A PT 9141089A PT 9141089 A PT9141089 A PT 9141089A PT 91410 A PT91410 A PT 91410A
Authority
PT
Portugal
Prior art keywords
genes
micro
identification
organism
culture
Prior art date
Application number
PT9141089A
Other languages
Portuguese (pt)
Other versions
PT91410B (en
Inventor
Annemarie Eveline Veenstra
Martinus Antonius Math Groenen
Pieter Van Solingen
Bertus Pieter Koekman
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of PT91410A publication Critical patent/PT91410A/en
Publication of PT91410B publication Critical patent/PT91410B/en

Links

Landscapes

  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to a process for the isolation of DNA fragments which express during the metabolism of micro-organisms and which are directly or indirectly essential for the production of a secondary metabolite or indirectly essential for the production of a secondary metabolite in that micro-organism, preferably a bacteria or a fungus, which comprises the stages of: a) scrutinizing a DNA bank prepared from the said micro- organism with sensors obtained from mRNA and DNA derived from a first culture of the said micro-organism which produces the said secondary metabolite, b) scrutinizing the said DNA bank with sensors obtained from mRNA or DNA derived from a second culture of the said micro-organism or a mutant thereof which does not produce the said secondary metabolite, and c) identification of the genes in the said first culture which are not substantially transcribed in the said second culture.
PT9141089A 1988-08-11 1989-08-09 PROCESS FOR IDENTIFYING AND USING BIOSAETIC OR REGULATING GENES FOR THE ENHANCED PRODUCTION OF SECONDARY METABOLITES PT91410B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88201714 1988-08-11
EP89200522 1989-03-03

Publications (2)

Publication Number Publication Date
PT91410A true PT91410A (en) 1990-03-08
PT91410B PT91410B (en) 1995-09-12

Family

ID=26115258

Family Applications (1)

Application Number Title Priority Date Filing Date
PT9141089A PT91410B (en) 1988-08-11 1989-08-09 PROCESS FOR IDENTIFYING AND USING BIOSAETIC OR REGULATING GENES FOR THE ENHANCED PRODUCTION OF SECONDARY METABOLITES

Country Status (1)

Country Link
PT (1) PT91410B (en)

Also Published As

Publication number Publication date
PT91410B (en) 1995-09-12

Similar Documents

Publication Publication Date Title
WO1998002550A3 (en) Microbial isoprene generation
ES8202362A1 (en) Genetically engineered microorganisms for massive production of amylolytic enzymes and process for preparing same.
EP1130043A3 (en) Polyhydroxyalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same
EP0066129A3 (en) Method for producing l-threonine by fermentation
EP0071023A3 (en) Method for producing l-isoleucine by fermentation
MXPA00008459A (en) New nucleotide sequences coding for the thre gene and process for the enzymatic production of l-threonine using coryneform bacteria.
DE3469038D1 (en) Process for the biotechnological preparation of poly-d(-)-3-hydroxybutyric acid
JPS5765198A (en) Fermentative production of l-glutamic acid
BG101400A (en) Biological product for the physico-chemical stabilisation of wine
MX244419B (en)
PT91410A (en) Process for the identification and use of biosynthetic genes or regulating genes for the improved production of secondary metabolites
AU7854694A (en) Genes for butyrobetaine/crotonobetaine-l-carnitine metabolism and their use for the microbiological production of l-carine
GB2330144A (en) Process for preparing doxorubicin
DE3064409D1 (en) Process for the production of cholesterol esterase
WO1996027670A3 (en) Enzymatic process for producing gdp-alpha-d-mannose, a gdp mannose pyrophosphorylase and phosphomannomutase suitable for that process, the extraction of the said enzymes, and an enzyme test
PT83368A (en) Process for propagating microorganisms in vivo by using cell lines which lack human class ii histocompatibility antigens
Grange et al. Differential deoxyribonucleic acid synthesis during microcycle conidiation in Neurospora crassa
CA2027059A1 (en) Process for the preparation of l-serine by an enzymatic method
GB1376573A (en) Process for the production of an amylase inhibitor
EP0341776A3 (en) Process for the incorporation of dna molecules into microorganisms with methyl-specific restriction systems
AU3157893A (en) Process for preparing neuraminidase
DE69722852D1 (en) Fermentative production of biotin
UA28162A (en) A method for genetic modification of strain of homobasidium fungi
ES2131001A1 (en) Process for increasing the production of clavulanic acid by the expression of biosynthetic regulator genes from Streptomyces clavuligerus
IL149389A0 (en) Method for producing a bank or collection of mutants and applications thereof

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19950503

PC3A Transfer or assignment

Free format text: 19981117 DSM N.V. NL