PT83930B - PROCESS FOR THE PREPARATION OF TIADIAZOL ANTIVIRAL AGENTS AND IN VITRO ANTIVIRAL METHOD USING THEM - Google Patents
PROCESS FOR THE PREPARATION OF TIADIAZOL ANTIVIRAL AGENTS AND IN VITRO ANTIVIRAL METHOD USING THEMInfo
- Publication number
- PT83930B PT83930B PT83930A PT8393086A PT83930B PT 83930 B PT83930 B PT 83930B PT 83930 A PT83930 A PT 83930A PT 8393086 A PT8393086 A PT 8393086A PT 83930 B PT83930 B PT 83930B
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- antiviral
- tiadiazol
- preparation
- vitro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
Abstract
(1) 1,3,4-Thiadiazole-2-cyanamide and derivs. of formula (I) and their salts are new. In (I), R1 = H; R2 = CN; or R1+R2 = =C(SR6)NH2 or =C(NH2)2; R6 = 1-4C alkyl, cyano-(1-4C)alkyl or pyridyl-(1-4C)alkyl. (2) In vitro antiviral method for protecting mammalian cells in culture comprises adding to the culture a cpd. (I) in which either (A) R1 = H; R2 = CN or =CH-NHR3; or R1+R2 = =C(NH2)2 or =CR5-NHR3(1); R3 = COOR4; R3(1) = H or COOR4; R4 = 1-10C alkyl, 2-10C alkenyl or Ph, each opt. substd.; R5 = H or SR6; R6 = 1-4C alkyl, cyano-(1-4C)alkyl or pyridyl-(1-4C)alkyl; or (B) as defined for (A) except that R1+R2 = =CR5NHR31 only; and R3, R31 = H or COOR4.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80966985A | 1985-12-16 | 1985-12-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT83930A PT83930A (en) | 1987-01-01 |
PT83930B true PT83930B (en) | 1989-06-30 |
Family
ID=25201936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT83930A PT83930B (en) | 1985-12-16 | 1986-12-15 | PROCESS FOR THE PREPARATION OF TIADIAZOL ANTIVIRAL AGENTS AND IN VITRO ANTIVIRAL METHOD USING THEM |
Country Status (15)
Country | Link |
---|---|
KR (1) | KR890004197B1 (en) |
CN (1) | CN1014242B (en) |
AT (1) | ATE59405T1 (en) |
DE (1) | DE3676673D1 (en) |
DK (1) | DK602786A (en) |
EG (1) | EG17724A (en) |
GR (1) | GR3001371T3 (en) |
HK (1) | HK2792A (en) |
HU (1) | HU198461B (en) |
IL (1) | IL80962A (en) |
MY (1) | MY101918A (en) |
NZ (1) | NZ218648A (en) |
PT (1) | PT83930B (en) |
SG (1) | SG98891G (en) |
ZA (1) | ZA869439B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108374182B (en) * | 2018-02-27 | 2019-08-16 | 广西师范大学 | A kind of new method of electrochemistry formated 1,2,4- thiadiazole compound |
-
1986
- 1986-12-15 ZA ZA869439A patent/ZA869439B/en unknown
- 1986-12-15 HU HU865218A patent/HU198461B/en not_active IP Right Cessation
- 1986-12-15 PT PT83930A patent/PT83930B/en not_active IP Right Cessation
- 1986-12-15 DK DK602786A patent/DK602786A/en not_active Application Discontinuation
- 1986-12-15 DE DE8686309740T patent/DE3676673D1/en not_active Expired - Lifetime
- 1986-12-15 KR KR1019860010710A patent/KR890004197B1/en not_active IP Right Cessation
- 1986-12-15 AT AT86309740T patent/ATE59405T1/en not_active IP Right Cessation
- 1986-12-15 EG EG765/86A patent/EG17724A/en active
- 1986-12-15 IL IL80962A patent/IL80962A/en not_active IP Right Cessation
- 1986-12-16 CN CN86108507A patent/CN1014242B/en not_active Expired
- 1986-12-16 NZ NZ218648A patent/NZ218648A/en unknown
-
1987
- 1987-09-29 MY MYPI87002224A patent/MY101918A/en unknown
-
1991
- 1991-01-24 GR GR91400075T patent/GR3001371T3/en unknown
- 1991-11-23 SG SG988/91A patent/SG98891G/en unknown
-
1992
- 1992-01-02 HK HK27/92A patent/HK2792A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN1014242B (en) | 1991-10-09 |
CN86108507A (en) | 1987-08-05 |
SG98891G (en) | 1992-01-17 |
IL80962A0 (en) | 1987-03-31 |
KR870006026A (en) | 1987-07-08 |
ATE59405T1 (en) | 1991-01-15 |
HK2792A (en) | 1992-01-10 |
MY101918A (en) | 1992-02-15 |
KR890004197B1 (en) | 1989-10-27 |
HU198461B (en) | 1989-10-30 |
HUT47092A (en) | 1989-01-30 |
EG17724A (en) | 1990-08-30 |
DE3676673D1 (en) | 1991-02-07 |
IL80962A (en) | 1991-12-15 |
NZ218648A (en) | 1989-07-27 |
ZA869439B (en) | 1988-08-31 |
PT83930A (en) | 1987-01-01 |
DK602786A (en) | 1987-06-17 |
DK602786D0 (en) | 1986-12-15 |
GR3001371T3 (en) | 1992-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19940630 |