PT83654B - Processo para a preparacao de polipeptideos que contem difluoro-cicloestatina - Google Patents

Processo para a preparacao de polipeptideos que contem difluoro-cicloestatina

Info

Publication number
PT83654B
PT83654B PT83654A PT8365486A PT83654B PT 83654 B PT83654 B PT 83654B PT 83654 A PT83654 A PT 83654A PT 8365486 A PT8365486 A PT 8365486A PT 83654 B PT83654 B PT 83654B
Authority
PT
Portugal
Prior art keywords
polipeptidees
cycloestratin
preparation
containing difluoro
difluoro
Prior art date
Application number
PT83654A
Other languages
English (en)
Other versions
PT83654A (en
Inventor
Dennis J Hoover
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT83654A publication Critical patent/PT83654A/pt
Publication of PT83654B publication Critical patent/PT83654B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT83654A 1985-11-01 1986-10-30 Processo para a preparacao de polipeptideos que contem difluoro-cicloestatina PT83654B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1985/002177 WO1987002675A1 (en) 1985-11-01 1985-11-01 Difluorocyclostatine containing polypeptides

Publications (2)

Publication Number Publication Date
PT83654A PT83654A (en) 1986-11-01
PT83654B true PT83654B (pt) 1989-05-31

Family

ID=22188920

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83654A PT83654B (pt) 1985-11-01 1986-10-30 Processo para a preparacao de polipeptideos que contem difluoro-cicloestatina

Country Status (12)

Country Link
EP (1) EP0222523A3 (pt)
JP (1) JPS63218697A (pt)
KR (1) KR890004365B1 (pt)
AU (1) AU592122B2 (pt)
DK (1) DK521186A (pt)
FI (1) FI872890A (pt)
HU (1) HU200473B (pt)
IL (1) IL80431A0 (pt)
NZ (1) NZ218116A (pt)
PT (1) PT83654B (pt)
WO (1) WO1987002675A1 (pt)
ZA (1) ZA868305B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599198A (en) * 1985-08-02 1986-07-08 Pfizer Inc. Intermediates in polypeptide synthesis
GB8619182D0 (en) * 1986-08-06 1986-09-17 Sandoz Ltd Peptides & derivatives
US5238923A (en) * 1989-05-26 1993-08-24 Warner-Lambert Company Amino-substituted heterocycles as renin inhibitors
US5071837A (en) * 1990-11-28 1991-12-10 Warner-Lambert Company Novel renin inhibiting peptides
IL108031A0 (en) * 1992-12-22 1994-04-12 Procter & Gamble Difluoro pentapeptide derivatives and pharmaceutical compositions containing them
US7348055B2 (en) 2001-12-21 2008-03-25 Surmodics, Inc. Reagent and method for providing coatings on surfaces

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1245217A (en) * 1981-12-10 1988-11-22 Joshua S. Boger Renin inhibitory peptides having phe su13 xx deletion
CA1254699A (en) * 1984-03-12 1989-05-23 Jasjit S. Bindra Renin inhibitors containing statine or derivatives thereof
DE3674131D1 (de) * 1985-04-19 1990-10-18 Upjohn Co Substituierte dihalo-statin-reninhemmungsmittel.
US4599198A (en) * 1985-08-02 1986-07-08 Pfizer Inc. Intermediates in polypeptide synthesis

Also Published As

Publication number Publication date
HUT46042A (en) 1988-09-28
PT83654A (en) 1986-11-01
EP0222523A2 (en) 1987-05-20
FI872890A0 (fi) 1987-06-30
NZ218116A (en) 1988-10-28
WO1987002675A1 (en) 1987-05-07
HU200473B (en) 1990-06-28
DK521186D0 (da) 1986-10-31
KR890004365B1 (ko) 1989-10-31
IL80431A0 (en) 1987-01-30
JPS63218697A (ja) 1988-09-12
FI872890A (fi) 1987-06-30
AU6458186A (en) 1987-05-07
AU592122B2 (en) 1990-01-04
KR870005011A (ko) 1987-06-04
EP0222523A3 (en) 1988-12-07
ZA868305B (en) 1988-06-29
DK521186A (da) 1987-05-02

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960531