PT81256A - Process for the preparation of 1,2,3,4,6,7,12,12b-octahydroindolo/2,3-a/quinolizin-1-yl-alkanecarboxylic acid amides and their therapeutically useful acid addition salts pharmaceutical compositions containing them - Google Patents

Process for the preparation of 1,2,3,4,6,7,12,12b-octahydroindolo/2,3-a/quinolizin-1-yl-alkanecarboxylic acid amides and their therapeutically useful acid addition salts pharmaceutical compositions containing them

Info

Publication number
PT81256A
PT81256A PT81256A PT8125685A PT81256A PT 81256 A PT81256 A PT 81256A PT 81256 A PT81256 A PT 81256A PT 8125685 A PT8125685 A PT 8125685A PT 81256 A PT81256 A PT 81256A
Authority
PT
Portugal
Prior art keywords
octahydroindolo
quinolizin
preparation
pharmaceutical compositions
addition salts
Prior art date
Application number
PT81256A
Other languages
English (en)
Other versions
PT81256B (pt
Inventor
Ferenc Soti
Csaba Szantay
Maria Incze
Zsuzsanna Balogh
Elemer Ezer
Judit Matuz
Laszlo Szporny
Gyorgy Hajos
Csaba Kuthi
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of PT81256A publication Critical patent/PT81256A/pt
Publication of PT81256B publication Critical patent/PT81256B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT81256A 1984-10-05 1985-10-04 Processo para a preparacao de amidas de acidos 1,2,3,4,,6,7,12,12b-octahidro-indolo{2,3-a}-quinolizin-1-il-alcanocarboxilicos e seus sais de adicao de acido terapeuticamente uteis e de composicoes farmaceuticas que os contem PT81256B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU843776A HU191454B (en) 1984-10-05 1984-10-05 Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof

Publications (2)

Publication Number Publication Date
PT81256A true PT81256A (en) 1985-11-01
PT81256B PT81256B (pt) 1987-10-20

Family

ID=10965440

Family Applications (1)

Application Number Title Priority Date Filing Date
PT81256A PT81256B (pt) 1984-10-05 1985-10-04 Processo para a preparacao de amidas de acidos 1,2,3,4,,6,7,12,12b-octahidro-indolo{2,3-a}-quinolizin-1-il-alcanocarboxilicos e seus sais de adicao de acido terapeuticamente uteis e de composicoes farmaceuticas que os contem

Country Status (23)

Country Link
US (1) US4782052A (pt)
EP (1) EP0177361A3 (pt)
JP (1) JPS61126086A (pt)
KR (1) KR860003254A (pt)
CN (1) CN85109716A (pt)
AU (1) AU578314B2 (pt)
CA (1) CA1267145A (pt)
DD (1) DD237659A5 (pt)
DK (1) DK453485A (pt)
ES (1) ES8701176A1 (pt)
FI (1) FI853867L (pt)
GR (1) GR852410B (pt)
HU (1) HU191454B (pt)
IL (1) IL76579A0 (pt)
IN (1) IN162609B (pt)
NO (1) NO161857B (pt)
NZ (1) NZ213710A (pt)
PH (1) PH23265A (pt)
PL (1) PL145678B1 (pt)
PT (1) PT81256B (pt)
SU (1) SU1470193A3 (pt)
YU (1) YU159085A (pt)
ZA (1) ZA857687B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582663B2 (en) * 1985-08-10 1989-04-06 John Wyeth & Brother Limited Sulphonamides

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565804A (en) * 1975-10-28 1980-04-23 Inverni Della Beffa Spa Alkaloid derivatives
ZA786426B (en) * 1977-11-25 1979-10-31 Scras New indulo(2,3-a)quinolizidines,preparation and therapeutic use
HU178700B (en) * 1978-02-10 1982-06-28 Richter Gedeon Vegyeszet Process for preparing 1,1-disubstituted octahydro-indolo/2,3-a/-quinolizines
US4353911A (en) * 1979-07-20 1982-10-12 Andre Buzas Indolo(2,3-a)quinolizidines, useful in increasing femoral and vertebral blood flow
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
DE3175900D1 (en) * 1981-11-18 1987-03-12 Thal Claude Indoloquinolizine derivatives, process for their preparation and their therapeutic use
DE3204960A1 (de) * 1982-02-12 1983-08-25 Fa. Dr. Willmar Schwabe, 7500 Karlsruhe Corynanthein-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194221B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound

Also Published As

Publication number Publication date
NO161857B (no) 1989-06-26
AU4832985A (en) 1986-04-10
US4782052A (en) 1988-11-01
KR860003254A (ko) 1986-05-21
PL255646A1 (en) 1986-10-21
DK453485A (da) 1986-04-06
FI853867L (fi) 1986-04-06
FI853867A0 (fi) 1985-10-04
NO853936L (no) 1986-04-07
PH23265A (en) 1989-06-23
EP0177361A3 (en) 1987-09-02
AU578314B2 (en) 1988-10-20
JPS61126086A (ja) 1986-06-13
CN85109716A (zh) 1986-10-08
IN162609B (pt) 1988-06-18
ZA857687B (en) 1986-05-28
PL145678B1 (en) 1988-10-31
YU159085A (en) 1988-04-30
ES8701176A1 (es) 1986-11-16
DD237659A5 (de) 1986-07-23
CA1267145A (en) 1990-03-27
PT81256B (pt) 1987-10-20
EP0177361A2 (en) 1986-04-09
ES547605A0 (es) 1986-11-16
GR852410B (pt) 1986-02-04
SU1470193A3 (ru) 1989-03-30
DK453485D0 (da) 1985-10-04
NZ213710A (en) 1988-08-30
IL76579A0 (en) 1986-02-28
HU191454B (en) 1987-02-27

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MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19910908