PT808172E - Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular - Google Patents

Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular

Info

Publication number
PT808172E
PT808172E PT96910309T PT96910309T PT808172E PT 808172 E PT808172 E PT 808172E PT 96910309 T PT96910309 T PT 96910309T PT 96910309 T PT96910309 T PT 96910309T PT 808172 E PT808172 E PT 808172E
Authority
PT
Portugal
Prior art keywords
treatment
inhibitor
angiotensin
conversation
combination
Prior art date
Application number
PT96910309T
Other languages
English (en)
Inventor
Todd E Maclaughlan
Alfonso T Perez
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT808172E publication Critical patent/PT808172E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT96910309T 1995-02-10 1996-02-09 Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular PT808172E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38685295A 1995-02-10 1995-02-10

Publications (1)

Publication Number Publication Date
PT808172E true PT808172E (pt) 2003-11-28

Family

ID=23527334

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96910309T PT808172E (pt) 1995-02-10 1996-02-09 Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular

Country Status (13)

Country Link
EP (2) EP1136078A3 (pt)
JP (1) JPH11507012A (pt)
KR (1) KR19980702099A (pt)
AT (1) ATE243529T1 (pt)
AU (1) AU5354196A (pt)
BR (1) BR9604882A (pt)
CA (1) CA2212713A1 (pt)
DE (1) DE69628821T2 (pt)
DK (1) DK0808172T3 (pt)
ES (1) ES2205023T3 (pt)
NZ (1) NZ305528A (pt)
PT (1) PT808172E (pt)
WO (1) WO1996024373A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1047450T3 (da) * 1997-12-23 2003-01-27 Warner Lambert Co Kombinationer af ACE-inhibitorer og MMP-inhibitorer
ATE457169T1 (de) * 1998-10-15 2010-02-15 Imp Innovations Ltd Verbindungen für die behandlung von gewichtsverlust
CZ20011590A3 (cs) 1998-11-06 2003-01-15 G. D. Searle & Co. Léčivo pro léčení kardiovaskulárních poruch a kompozice s obsahem inhibitoru enzymu konvertujícího angiotensin, antagonisty aldosteronu, kličkového diuretika a digoxinu
SE9903028D0 (sv) * 1999-08-27 1999-08-27 Astra Ab New use
WO2001080895A2 (en) * 2000-04-26 2001-11-01 First Horizon Pharmaceutical Corporation Methods and compositions for the treatment of cardiac indications
US20050014732A1 (en) * 2003-03-14 2005-01-20 Pharmacia Corporation Combination of an aldosterone receptor antagonist and an anti-diabetic agent
CL2004000544A1 (es) * 2003-03-18 2005-01-28 Pharmacia Corp Sa Organizada B Uso de una combinacion farmaceutica, de un antagonista del receptor de aldosterona y un inhibidor de endopeptidasa neutral, util para el tratamiento y prevencion de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopati
KR101245877B1 (ko) 2006-08-04 2013-03-20 메디치니쉐 호흐슐레 하노버 Gdf-15 를 바탕으로 한, 심장 중재의 위험도를 평가하는수단 및 방법
FR2917975B1 (fr) 2007-06-26 2009-10-16 Ceva Sante Animale Sa Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains
ES2836508T3 (es) * 2009-03-26 2021-06-25 Ajay Gupta Composiciones y métodos para el tratamiento de la enfermedad renal

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217347A (en) * 1977-12-27 1980-08-12 E. R. Squibb & Sons, Inc. Method of treating hypertension and medicaments therefor
WO1995009625A1 (en) * 1993-10-04 1995-04-13 Handforth Investments Ltd. Use of amiodarone for the treatment of heart failure

Also Published As

Publication number Publication date
DE69628821T2 (de) 2004-05-06
ATE243529T1 (de) 2003-07-15
EP1136078A3 (en) 2002-07-24
EP1136078A2 (en) 2001-09-26
ES2205023T3 (es) 2004-05-01
CA2212713A1 (en) 1996-08-15
KR19980702099A (ko) 1998-07-15
AU5354196A (en) 1996-08-27
BR9604882A (pt) 1998-05-19
EP0808172B1 (en) 2003-06-25
EP0808172A2 (en) 1997-11-26
DK0808172T3 (da) 2003-10-20
WO1996024373A2 (en) 1996-08-15
NZ305528A (en) 2001-05-25
DE69628821D1 (de) 2003-07-31
WO1996024373A3 (en) 1996-09-26
JPH11507012A (ja) 1999-06-22

Similar Documents

Publication Publication Date Title
BR9915134A (pt) Co-terapia e terapia combinada para o tratamento de distúrbio cardiovascular em um indivìduo, e, composição
MY121008A (en) Combination therapy comprising atorvastatin and an antihypertensive agent.
MXPA05000832A (es) Metodos de diagnosticar y tratar pre-eclampsia o eclampsia.
WO2000038665A3 (en) Use of an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
WO1997044063A3 (en) Dha-pharmaceutical agent conjugates
NZ332720A (en) Therapeutic uses of bactericidal/permeability increasing (BPI) protein to treat human meningococcemia
HUS1300069I1 (hu) Dextrometorfánt és kinidint tartalmazó gyógyászati készítmények neurológiai rendellenességek kezelésére
AU3920900A (en) Compounds and methods to treat cardiac failure and other disorders
GB9700396D0 (en) Photochemotherapeutic compositions
MXPA00007388A (es) Metodos para tratar la pigmentacion de la piel.
CA2081564A1 (en) Synergistic therapeutic compositions and methods
NZ332721A (en) Use of bactericidal/permeability increasing (BPI) protein sometimes in conjunction with a thrombolytic agent to treat thrombotic disorders
PT808172E (pt) Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular
MXPA01009035A (es) Terapia de combinacion de inhibidor de enzima convertidora de angiotensina y antagonista de aldosterona epoxi-esteroidea para tratamiento de enfermedad cardiovascular.
ZA964761B (en) Peptidyl heterocycles useful in the treatment of thrombin related disorders.
WO1998022101A3 (en) Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents
WO2000013712A3 (en) Methods and compositions for the prevention or treatment of cancer
TR199801988T2 (xx) Kalp yetmezli�inin endotelin antagonistleri ile tedavisi i�in y�ntem.
WO1996024372A3 (en) Combination of angiotensin converting enzyme inhibitor, side-effect-reduced amount of aldosterone antagonist and diuretic
ATE291425T1 (de) R-eliprodil zur behandlung von glaucoma
EP1234585A3 (en) Methods and compositions for the prevention or treatment of cancer
LT2001045A (en) Compositions and use thereof for downmodulating the immune response to therapeutic proteins
WO2001046405A3 (en) Modulation of pax-2 for controlled apoptosis or survival of cells
HK1058305A1 (en) Combinations of dalfopristine/quinupristine with cefpirome
MXPA02004704A (es) Analogos de acido hidroxieicosatetraenoico y sus metodos de uso en el tratamiento de trastornos de resequedad del ojo.