PT80689A - Process for the preparation of novel chroman and chromene compounds having pharmacological activity pharmaceutical compositions containing same and theier use in the treatment of mammals - Google Patents
Process for the preparation of novel chroman and chromene compounds having pharmacological activity pharmaceutical compositions containing same and theier use in the treatment of mammalsInfo
- Publication number
- PT80689A PT80689A PT80689A PT8068985A PT80689A PT 80689 A PT80689 A PT 80689A PT 80689 A PT80689 A PT 80689A PT 8068985 A PT8068985 A PT 8068985A PT 80689 A PT80689 A PT 80689A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- hydrogen
- preparation
- pharmacological activity
- alkylcarbonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848415931A GB8415931D0 (en) | 1984-06-22 | 1984-06-22 | Active compounds |
GB848431479A GB8431479D0 (en) | 1984-12-13 | 1984-12-13 | Active compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
PT80689A true PT80689A (en) | 1985-07-01 |
PT80689B PT80689B (en) | 1986-12-09 |
Family
ID=26287908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT80689A PT80689B (en) | 1984-06-22 | 1985-06-21 | Process for the preparation of novel chroman and chromene compounds having pharmacological activity pharmaceutical compositions containing same and theier use in the treatment of mammals |
Country Status (12)
Country | Link |
---|---|
US (1) | US4631282A (pt) |
EP (1) | EP0172352B1 (pt) |
JP (1) | JPS6112685A (pt) |
AT (1) | ATE56007T1 (pt) |
AU (1) | AU579378B2 (pt) |
CA (1) | CA1250294A (pt) |
DE (1) | DE3579390D1 (pt) |
DK (1) | DK279785A (pt) |
ES (1) | ES8703149A1 (pt) |
GR (1) | GR851517B (pt) |
NZ (1) | NZ212500A (pt) |
PT (1) | PT80689B (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5387587A (en) * | 1986-12-23 | 1995-02-07 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
FR2628424B1 (fr) * | 1988-03-09 | 1990-12-28 | Sanofi Sa | Derives du dimethyl-2,2 chromannol-3 procede d'obtention et compositions pharmaceutiques en contenant |
IL86798A (en) * | 1987-06-23 | 1992-12-01 | Sanofi Sa | 2,2-dimethylchroman-3-ol derivatives, their preparation and pharmaceutical compositions containing them |
FR2625744B1 (fr) * | 1988-01-12 | 1990-07-06 | Sanofi Sa | Derives du dimethyl-2,2 chromannol-3 procede d'obtention et compositions pharmaceutiques en contenant |
US5284838A (en) * | 1987-06-23 | 1994-02-08 | Elf Sanofi | Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma |
US4971982A (en) * | 1987-07-06 | 1990-11-20 | Hoffmann-La Roche Inc. | Benzopyran derivatives |
US5021432A (en) * | 1988-04-26 | 1991-06-04 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzopyran compound and its pharmaceutical use |
US4988723A (en) * | 1988-06-02 | 1991-01-29 | Fujisawa Pharmaceutical Co., Ltd. | Benzopyran derivatives and their use as anti-hypertensives |
FR2637896B1 (fr) * | 1988-10-17 | 1990-11-30 | Adir | Nouveaux derives de l'amino chromanol, leur procede de preparation et les compositions pharmaceutiques les renfermant |
US5072006A (en) * | 1988-12-09 | 1991-12-10 | Recherche Syntex France S.A. | Novel benzopyranylpyrrolinone derivatives |
US4997846A (en) * | 1988-12-09 | 1991-03-05 | Researche Syntex France, S.A. | Novel benzopyranylpyrrolinone derivatives |
DE3924417A1 (de) * | 1989-07-24 | 1991-01-31 | Merck Patent Gmbh | Chromanderivate |
DE3926001A1 (de) * | 1989-08-05 | 1991-02-07 | Merck Patent Gmbh | Chromanderivate |
WO1991009031A1 (en) * | 1989-12-11 | 1991-06-27 | Beecham Group Plc | Trifluoromethyl substituted compounds and a pharmaceutical composition |
US5401848A (en) * | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
WO1992012973A1 (fr) * | 1991-01-23 | 1992-08-06 | Nippon Kayaku Kabushiki Kaisha | Derive de chromane |
SE9703377D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | New compounds |
AU2002217742B2 (en) | 2001-01-16 | 2008-02-21 | Astrazeneca Ab | Therapeutic heterocyclic compounds |
ATE543813T1 (de) * | 2005-09-01 | 2012-02-15 | Janssen Pharmaceutica Nv | Neue benzopyranderivate als kaliumkanalöffner |
EP1940516A2 (en) * | 2005-09-01 | 2008-07-09 | Janssen Pharmaceutica, N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
RU2604734C2 (ru) * | 2010-12-22 | 2016-12-10 | БИАЛ-ПОРТЕЛА энд КА., С.А. | Кристаллическая форма и способ ее очистки |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4062870A (en) * | 1974-05-31 | 1977-12-13 | Beecham Group Limited | Chroman derivatives |
GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
EP0009912B1 (en) * | 1978-10-04 | 1983-06-22 | Beecham Group Plc | Chromanol derivatives, a process for their preparation and pharmaceutical compositions comprising them |
DE3064286D1 (en) * | 1979-09-28 | 1983-08-25 | Beecham Group Plc | Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them |
DE3064285D1 (en) * | 1979-09-28 | 1983-08-25 | Beecham Group Plc | Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them |
US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
GB2107706A (en) * | 1981-09-25 | 1983-05-05 | Beecham Group Plc | Benzopyrans |
EP0091748B1 (en) * | 1982-04-08 | 1986-06-18 | Beecham Group Plc | Antihypertensive benzopyranols |
EP0093535B1 (en) * | 1982-04-28 | 1986-12-30 | Beecham Group Plc | Novel chromenes and chromans |
DE3364734D1 (en) * | 1982-10-19 | 1986-08-28 | Beecham Group Plc | Novel chromans and chromenes |
-
1985
- 1985-06-15 EP EP85107477A patent/EP0172352B1/en not_active Expired - Lifetime
- 1985-06-15 AT AT85107477T patent/ATE56007T1/de not_active IP Right Cessation
- 1985-06-15 DE DE8585107477T patent/DE3579390D1/de not_active Expired - Fee Related
- 1985-06-20 NZ NZ212500A patent/NZ212500A/xx unknown
- 1985-06-20 AU AU43897/85A patent/AU579378B2/en not_active Ceased
- 1985-06-20 CA CA000484678A patent/CA1250294A/en not_active Expired
- 1985-06-20 GR GR851517A patent/GR851517B/el unknown
- 1985-06-20 DK DK279785A patent/DK279785A/da not_active Application Discontinuation
- 1985-06-20 US US06/746,968 patent/US4631282A/en not_active Expired - Fee Related
- 1985-06-21 PT PT80689A patent/PT80689B/pt unknown
- 1985-06-21 JP JP60134468A patent/JPS6112685A/ja active Granted
- 1985-06-21 ES ES544454A patent/ES8703149A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
GR851517B (pt) | 1985-11-25 |
JPS6112685A (ja) | 1986-01-21 |
NZ212500A (en) | 1988-11-29 |
AU4389785A (en) | 1986-01-02 |
EP0172352A2 (en) | 1986-02-26 |
DK279785A (da) | 1985-12-23 |
EP0172352A3 (en) | 1986-12-03 |
EP0172352B1 (en) | 1990-08-29 |
US4631282A (en) | 1986-12-23 |
CA1250294A (en) | 1989-02-21 |
AU579378B2 (en) | 1988-11-24 |
ES544454A0 (es) | 1987-02-01 |
DK279785D0 (da) | 1985-06-20 |
JPH0566953B2 (pt) | 1993-09-22 |
ATE56007T1 (de) | 1990-09-15 |
PT80689B (en) | 1986-12-09 |
DE3579390D1 (de) | 1990-10-04 |
ES8703149A1 (es) | 1987-02-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT80689A (en) | Process for the preparation of novel chroman and chromene compounds having pharmacological activity pharmaceutical compositions containing same and theier use in the treatment of mammals | |
ES8604189A1 (es) | Un procedimiento para la preparacion de nuevos derivados delcromano | |
ES8601180A1 (es) | Un procedimiento para la preparacion de nuevos cromanos y cromenos. | |
ES8407036A1 (es) | Un procedimiento para la preparacion de nuevos cromenos y cromanos. | |
ES522937A0 (es) | Un procedimiento para la preparacion de nuevos benzopiranos. como divisional de la solicitud de patente n 515.921no de 23 de septiembre de 1982. | |
ES8607964A1 (es) | Un procedimiento para la preparacion del isomero (3s, 4r) de un compuesto | |
IL105372A0 (en) | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and pharmaceutical compositions containing them | |
ES2143541T3 (es) | Composicion farmaceutica que contiene compuestos de tipo biciclico. | |
NZ504991A (en) | Pharmaceutical compositions containing micronized benzopyran or pyridopyran derivatives, and their use as medicaments | |
IL93229A0 (en) | Process for the preparation of a pure isomer of a benzopyran derivative |