PT80432B - Compounds - Google Patents
CompoundsInfo
- Publication number
- PT80432B PT80432B PT80432A PT8043285A PT80432B PT 80432 B PT80432 B PT 80432B PT 80432 A PT80432 A PT 80432A PT 8043285 A PT8043285 A PT 8043285A PT 80432 B PT80432 B PT 80432B
- Authority
- PT
- Portugal
- Prior art keywords
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848412184A GB8412184D0 (en) | 1984-05-12 | 1984-05-12 | Biologically active nitrogen heterocycles |
| GB858500417A GB8500417D0 (en) | 1985-01-08 | 1985-01-08 | Biologically active nitrogen heterocycles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT80432A PT80432A (en) | 1985-06-01 |
| PT80432B true PT80432B (en) | 1987-04-16 |
Family
ID=26287736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT80432A PT80432B (en) | 1984-05-12 | 1985-05-10 | Compounds |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0164204A1 (enEXAMPLES) |
| AU (1) | AU4227685A (enEXAMPLES) |
| DK (1) | DK203985A (enEXAMPLES) |
| ES (1) | ES8609275A1 (enEXAMPLES) |
| FI (1) | FI851837L (enEXAMPLES) |
| GR (1) | GR851131B (enEXAMPLES) |
| IL (1) | IL75147A0 (enEXAMPLES) |
| NO (1) | NO851877L (enEXAMPLES) |
| PT (1) | PT80432B (enEXAMPLES) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4711888A (en) * | 1985-07-24 | 1987-12-08 | Pfizer Inc. | Hydroxy and alkoxy pyrimidines |
| DE3751742T3 (de) † | 1986-01-13 | 2002-11-21 | American Cyanamid Co., Wayne | 4,5,6-Substituierte 2-Pyrimidinamine |
| GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
| US5064963A (en) * | 1990-04-25 | 1991-11-12 | American Cyanamid Company | Process for the synthesis of n-(3-(1h-imidazol-1-yl)phenyl-4-(substituted)-2-pyrimidinamines |
| WO1992013844A1 (en) * | 1991-01-31 | 1992-08-20 | Warner-Lambert Company | Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines |
| US5177079A (en) * | 1991-01-31 | 1993-01-05 | Warner-Lambert Company | 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents |
| US5248682A (en) * | 1991-01-31 | 1993-09-28 | Warner-Lambert Company | 2-substituted-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents |
| US5270319A (en) * | 1991-09-09 | 1993-12-14 | Warner-Lambert Company | 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents |
| US5220025A (en) * | 1992-02-24 | 1993-06-15 | Warner-Lambert Company | 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents |
| US5196431A (en) * | 1992-02-24 | 1993-03-23 | Warner-Lambert Company | 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents |
| US5276186A (en) * | 1992-03-11 | 1994-01-04 | Ciba-Geigy Corporation | Process for the production of guanidine derivatives |
| US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US5516775A (en) * | 1992-08-31 | 1996-05-14 | Ciba-Geigy Corporation | Further use of pyrimidine derivatives |
| WO1995009847A1 (en) * | 1993-10-01 | 1995-04-13 | Ciba-Geigy Ag | Pyrimidineamine derivatives and processes for the preparation thereof |
| US5543520A (en) * | 1993-10-01 | 1996-08-06 | Ciba-Geigy Corporation | Pyrimidine derivatives |
| EP0672041B1 (en) * | 1993-10-01 | 2001-11-14 | Novartis AG | Pharmacologically active pyridine derivatives and processes for the preparation thereof |
| WO1997033883A1 (en) * | 1996-03-13 | 1997-09-18 | Smithkline Beecham Corporation | Novel pyrimidine compounds useful in treating cytokine mediated diseases |
| US6184226B1 (en) | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| EP1274705A1 (en) | 2000-03-29 | 2003-01-15 | Cyclacel Limited | 2-substituted 4-heteroaryl-pyrimidines and their use in the treatment of proliferative disorders |
| HUP0402106A3 (en) | 2001-11-01 | 2009-07-28 | Janssen Pharmaceutica Nv | Heteroaryl amines as glycogen synthase kinase 3 beta inhibitors, process for their preparation and pharmaceutical compositions containing them |
| NZ531854A (en) * | 2001-11-01 | 2006-03-31 | Janssen Pharmaceutica Nv | Aminobenzamide derivatives as glycogen synthase kinase 3beta inhibitors |
| AR038368A1 (es) | 2002-02-01 | 2005-01-12 | Novartis Ag | Compuestos n-pirimidin-2-il-aminas sustituidas como inhibidores de ige, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de un medicamento |
| WO2005012262A1 (en) | 2003-07-30 | 2005-02-10 | Cyclacel Limited | 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors |
| JP4790703B2 (ja) | 2004-04-07 | 2011-10-12 | 武田薬品工業株式会社 | 環式化合物 |
| PL1799230T3 (pl) | 2004-08-27 | 2013-05-31 | Cyclacel Ltd | Purynowe i pirymidynowe inhibitory CDK i ich zastosowanie do leczenia chorób autoimmunologicznych |
| RU2436776C2 (ru) | 2005-09-27 | 2011-12-20 | Айрм Ллк | ДИАРИЛАМИН-СОДЕРЖАЩИЕ СОЕДИНЕНИЯ, КОМПОЗИЦИИ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ МОДУЛЯТОРОВ РЕЦЕПТОРОВ с-КIT |
| GB0606774D0 (en) * | 2006-04-03 | 2006-05-10 | Novartis Ag | Organic compounds |
| EP2148874B1 (en) | 2007-05-04 | 2012-02-08 | Irm Llc | Pyrimidine derivatives and compositions as c-kit and pdgfr kinase inhibitors |
| ES2477878T3 (es) * | 2007-08-22 | 2014-07-18 | Irm Llc | Compuestos y composiciones de 5-(4-(aloalcoxi)fenil)pirimidin-2-amina como inhibidores de quinasas |
| KR101171488B1 (ko) | 2007-08-22 | 2012-08-07 | 아이알엠 엘엘씨 | 키나제 억제제로서의 2-헤테로아릴아미노-피리미딘 유도체 |
| JP2011520975A (ja) * | 2008-05-19 | 2011-07-21 | ユニヴァーシティ オブ テネシー リサーチ ファウンデーション，ザ | ピリミジンの非古典的カンナビノイド化合物及び関連する使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496179A (en) * | 1967-10-11 | 1970-02-17 | Pfizer & Co C | 2-amino-3,4-dihydroquinazolines |
| US3663706A (en) * | 1969-09-29 | 1972-05-16 | Pfizer | Use of 2,4-diaminoquinazolines as hypotensive agents |
| CA961855A (en) * | 1969-10-16 | 1975-01-28 | Eli Lilly And Company | Immunosuppressants and anti-viral agents |
| US3900476A (en) * | 1973-05-17 | 1975-08-19 | Upjohn Co | 2(2'-pyrimidylamino)quinazolines and their preparation |
| US4010269A (en) * | 1975-06-16 | 1977-03-01 | The Upjohn Company | Antiviral quinazoline compositions and methods of use |
| DE3220118A1 (de) * | 1982-05-28 | 1983-12-01 | Bayer Ag, 5090 Leverkusen | Alkylenverbrueckte guanidinothiazolderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1985
- 1985-04-25 EP EP85302902A patent/EP0164204A1/en not_active Withdrawn
- 1985-05-08 DK DK203985A patent/DK203985A/da not_active Application Discontinuation
- 1985-05-09 IL IL75147A patent/IL75147A0/xx unknown
- 1985-05-09 FI FI851837A patent/FI851837L/fi not_active Application Discontinuation
- 1985-05-09 GR GR851131A patent/GR851131B/el unknown
- 1985-05-10 PT PT80432A patent/PT80432B/pt unknown
- 1985-05-10 AU AU42276/85A patent/AU4227685A/en not_active Abandoned
- 1985-05-10 ES ES543047A patent/ES8609275A1/es not_active Expired
- 1985-05-10 NO NO851877A patent/NO851877L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT80432A (en) | 1985-06-01 |
| DK203985A (da) | 1985-11-13 |
| FI851837A7 (fi) | 1985-11-13 |
| GR851131B (enEXAMPLES) | 1985-11-25 |
| NO851877L (no) | 1985-11-13 |
| FI851837L (fi) | 1985-11-13 |
| FI851837A0 (fi) | 1985-05-09 |
| IL75147A0 (en) | 1985-09-29 |
| AU4227685A (en) | 1985-11-14 |
| ES8609275A1 (es) | 1986-07-16 |
| ES543047A0 (es) | 1986-07-16 |
| EP0164204A1 (en) | 1985-12-11 |
| DK203985D0 (da) | 1985-05-08 |
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