PT75160A - Tricyclic derivatives of substituted pyrrole acids as analgesic and inflammatory agents - Google Patents

Tricyclic derivatives of substituted pyrrole acids as analgesic and inflammatory agents

Info

Publication number
PT75160A
PT75160A PT75160A PT7516082A PT75160A PT 75160 A PT75160 A PT 75160A PT 75160 A PT75160 A PT 75160A PT 7516082 A PT7516082 A PT 7516082A PT 75160 A PT75160 A PT 75160A
Authority
PT
Portugal
Prior art keywords
analgesic
inflammatory agents
substituted pyrrole
tricyclic derivatives
pyrrole acids
Prior art date
Application number
PT75160A
Other languages
English (en)
Portuguese (pt)
Inventor
James B Doherty
Conrad P Dorn
Bruce E Witzel
Debra L Allison
Tsung-Ying Shen
Paul E Finke
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/329,842 external-priority patent/US4380645A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT75160A publication Critical patent/PT75160A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT75160A 1981-06-30 1982-06-30 Tricyclic derivatives of substituted pyrrole acids as analgesic and inflammatory agents PT75160A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27914081A 1981-06-30 1981-06-30
US06/329,842 US4380645A (en) 1981-12-11 1981-12-11 Process for preparing Benzoxepino- or Benzthiapino[4,3-b]pyrrole-2-acetic acids

Publications (1)

Publication Number Publication Date
PT75160A true PT75160A (en) 1982-07-01

Family

ID=26959474

Family Applications (1)

Application Number Title Priority Date Filing Date
PT75160A PT75160A (en) 1981-06-30 1982-06-30 Tricyclic derivatives of substituted pyrrole acids as analgesic and inflammatory agents

Country Status (10)

Country Link
EP (1) EP0068460A1 (enExample)
KR (1) KR840000555A (enExample)
AU (1) AU8509882A (enExample)
CA (1) CA1185971A (enExample)
DK (1) DK291382A (enExample)
ES (1) ES8308885A1 (enExample)
FI (1) FI822313L (enExample)
GR (1) GR74929B (enExample)
NO (1) NO822232L (enExample)
PT (1) PT75160A (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025640A (en) * 1975-08-26 1977-05-24 American Hoechst Corporation Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof
EP0024807B1 (en) * 1979-07-28 1983-11-02 Beecham Group Plc Benzocycloheptapyrrolealkanoic acids and their derivatives, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK291382A (da) 1982-12-31
CA1185971A (en) 1985-04-23
ES513560A0 (es) 1983-10-01
ES8308885A1 (es) 1983-10-01
KR840000555A (ko) 1984-02-25
EP0068460A1 (en) 1983-01-05
NO822232L (no) 1983-01-03
GR74929B (enExample) 1984-07-12
FI822313A7 (fi) 1982-12-31
FI822313L (fi) 1982-12-31
AU8509882A (en) 1983-01-06
FI822313A0 (fi) 1982-06-29

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