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Application filed by Byk Gulden Lomberg Chem FabfiledCriticalByk Gulden Lomberg Chem Fab
Priority to PT7452982ApriorityCriticalpatent/PT74529B/en
Publication of PT74529ApublicationCriticalpatent/PT74529A/en
Publication of PT74529BpublicationCriticalpatent/PT74529B/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Epoxy Compounds
(AREA)
Abstract
Cycloalkyl-substd. oxirane-2-carboxylic acid derivs. of formula (I), and when R is H, their salts are new. R is H or 1-4C alkyl; Y is O or CH2; m is 0-6; n is 0-6; p is 2-11; the sum of m, n and p is 6-15, and m is other than 0 or 1 when Y is O. (I) are hypoglycaemic and hypoketonaemic agents with a relatively short duration of action. They are suitable for the treatment and prophylaxis of diseases due to disorders of glucose and lipid metabolism such as diabetes or diseases associated with pathologically elevated ketone body production. Ethyl 2-(5-cyclohexylpentyl) oxirane-2-carboxylate and ethyl 2-(2-(3-cyclohexyl propoxy)ethyl) -oxirane-2-carboxylate, are specifically claimed.
PT7452982A1982-03-041982-03-04Process for the preparation of epoxycycloalkylalkanecarboxilic acids
PT74529B
(en)
10-Bromosandwicine and 10-bromoisosandwicine, as well as their additions salts with pharmacolical acceptable acids process for their preparation and their use.