PT73763B - Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent - Google Patents

Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent

Info

Publication number
PT73763B
PT73763B PT7376381A PT7376381A PT73763B PT 73763 B PT73763 B PT 73763B PT 7376381 A PT7376381 A PT 7376381A PT 7376381 A PT7376381 A PT 7376381A PT 73763 B PT73763 B PT 73763B
Authority
PT
Portugal
Prior art keywords
benzofenantridine
alkaloids
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
PT7376381A
Other languages
English (en)
Portuguese (pt)
Other versions
PT73763A (fr
Original Assignee
Quatrum Empresa Nacional De Qu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quatrum Empresa Nacional De Qu filed Critical Quatrum Empresa Nacional De Qu
Priority to PT7376381A priority Critical patent/PT73763B/fr
Publication of PT73763A publication Critical patent/PT73763A/fr
Priority to DE19823236455 priority patent/DE3236455A1/de
Priority to NL8203839A priority patent/NL8203839A/nl
Priority to BR8205780A priority patent/BR8205780A/pt
Priority to GB08228066A priority patent/GB2108955B/en
Priority to IN1179/CAL/82A priority patent/IN155552B/en
Publication of PT73763B publication Critical patent/PT73763B/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT7376381A 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent PT73763B (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
PT7376381A PT73763B (fr) 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent
DE19823236455 DE3236455A1 (de) 1981-10-01 1982-10-01 Epoxide von benzophenanthridinalkaloiden, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
NL8203839A NL8203839A (nl) 1981-10-01 1982-10-01 Nieuwe epoxyden van benzofenanthridine-alkaloiden, nieuwe farmaceutische preparaten die deze alkaloiden bevatten en werkwijzen voor de bereiding van zowel de nieuwe alkaloiden als de farmaceutische preparaten.
BR8205780A BR8205780A (pt) 1981-10-01 1982-10-01 Processo para a preparacao de novos epoxidos de alcaloides-benzenofenantridinicos e processo para a preparacao de composicoes
GB08228066A GB2108955B (en) 1981-10-01 1982-10-01 Chemical compounds
IN1179/CAL/82A IN155552B (fr) 1981-10-01 1982-10-12

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT7376381A PT73763B (fr) 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
PT73763A PT73763A (fr) 1981-11-01
PT73763B true PT73763B (fr) 1983-10-26

Family

ID=20082989

Family Applications (1)

Application Number Title Priority Date Filing Date
PT7376381A PT73763B (fr) 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent

Country Status (6)

Country Link
BR (1) BR8205780A (fr)
DE (1) DE3236455A1 (fr)
GB (1) GB2108955B (fr)
IN (1) IN155552B (fr)
NL (1) NL8203839A (fr)
PT (1) PT73763B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140328A (en) * 1997-12-12 2000-10-31 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
US6740650B2 (en) 1999-10-29 2004-05-25 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
AU2002352708A1 (en) 2001-11-14 2003-05-26 Edmond J. Lavoie Cytotoxic agents
AU2002364953A1 (en) 2001-11-14 2003-06-17 Edmond J. Lavoie Topoisomerase poison agents
CA2467279A1 (fr) 2001-11-14 2003-06-26 Edmond J. Lavoie Agents poisons de topoisomerases solubilises
JP4628675B2 (ja) 2001-11-14 2011-02-09 ラトガーズ，ザ ステイト ユニバーシティ 可溶化トポイソメラーゼ毒
WO2004014918A1 (fr) 2002-08-09 2004-02-19 Rutgers, The State University Agents de la topoisomerase substitues par nitro et amino
AU2003268075A1 (en) 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted dibenzonaphthyridines as topoisomerase agents
AU2003265405A1 (en) 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted heterocycles as topoisomerase i targeting agents
CA2510337C (fr) 2002-11-12 2013-01-08 Rutgers, The State University Of New Jersey Agents ciblant les topoisomerases
PT2403856E (pt) 2009-03-06 2013-03-25 Univ Rutgers Derivados de metilendioxibenzo[i]fenantridina utilizados para tratar o cancro
WO2010127363A1 (fr) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Inhibiteurs de topoisomérase
CN109219610A (zh) 2016-04-04 2019-01-15 新泽西州立拉特格斯大学 拓扑异构酶毒物

Also Published As

Publication number Publication date
DE3236455A1 (de) 1983-05-05
PT73763A (fr) 1981-11-01
GB2108955B (en) 1985-08-21
GB2108955A (en) 1983-05-25
NL8203839A (nl) 1983-05-02
IN155552B (fr) 1985-02-16
BR8205780A (pt) 1983-09-06

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Effective date: 19950430