PT68428A - Process for the preparation of thienamycin by enzymatic cleavage of n-acyl-thienamycins - Google Patents

Process for the preparation of thienamycin by enzymatic cleavage of n-acyl-thienamycins

Info

Publication number
PT68428A
PT68428A PT68428A PT6842878A PT68428A PT 68428 A PT68428 A PT 68428A PT 68428 A PT68428 A PT 68428A PT 6842878 A PT6842878 A PT 6842878A PT 68428 A PT68428 A PT 68428A
Authority
PT
Portugal
Prior art keywords
thienamycins
thienamycin
acyl
preparation
enzymatic cleavage
Prior art date
Application number
PT68428A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT68428A publication Critical patent/PT68428A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT68428A 1977-08-19 1978-08-16 Process for the preparation of thienamycin by enzymatic cleavage of n-acyl-thienamycins PT68428A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/825,883 US4162193A (en) 1977-08-19 1977-08-19 Enzymatic cleavage of N-acyl-thienamycins

Publications (1)

Publication Number Publication Date
PT68428A true PT68428A (en) 1978-09-01

Family

ID=25245138

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68428A PT68428A (en) 1977-08-19 1978-08-16 Process for the preparation of thienamycin by enzymatic cleavage of n-acyl-thienamycins

Country Status (9)

Country Link
US (1) US4162193A (pt)
EP (1) EP0000931B1 (pt)
JP (1) JPS5446890A (pt)
DE (1) DE2861737D1 (pt)
DK (1) DK365478A (pt)
ES (1) ES472701A1 (pt)
IE (1) IE47315B1 (pt)
IT (1) IT1106626B (pt)
PT (1) PT68428A (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02135843U (pt) * 1988-11-08 1990-11-13

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1111778B (de) * 1959-04-18 1961-07-27 Bayer Ag Verfahren zur Herstellung von 6-Aminopenicillansaeure
CH475284A (de) * 1963-11-19 1969-07-15 Ciba Geigy Verfahren zur Herstellung von Desacetyl-7-amino-cephalosporansäure
JPS5417030B2 (pt) * 1972-12-06 1979-06-27
GB1474519A (pt) * 1973-05-14 1977-05-25
JPS5713280B2 (pt) * 1974-03-11 1982-03-16
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
DK497476A (da) * 1975-11-24 1977-05-25 Merck & Co Inc Fremgangsmade til fremstilling af et antibiotisk stof
SE7800979L (sv) * 1977-02-11 1978-08-12 Merck & Co Inc Antibiotikum

Also Published As

Publication number Publication date
DK365478A (da) 1979-02-20
ES472701A1 (es) 1979-02-16
IE47315B1 (en) 1984-02-22
US4162193A (en) 1979-07-24
JPS6210639B2 (pt) 1987-03-07
DE2861737D1 (en) 1982-05-27
EP0000931A1 (en) 1979-03-07
IT7850747A0 (it) 1978-08-16
IE781674L (en) 1979-02-19
IT1106626B (it) 1985-11-11
EP0000931B1 (en) 1982-04-14
JPS5446890A (en) 1979-04-13

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