PT66272A - L-Isomers of alpha-ureido-acetamido-cephalosporins - more active against beta-lactamase producing bacteria than corresp. D-isomers - Google Patents

L-Isomers of alpha-ureido-acetamido-cephalosporins - more active against beta-lactamase producing bacteria than corresp. D-isomers

Info

Publication number
PT66272A
PT66272A PT197766272A PT6627277A PT66272A PT 66272 A PT66272 A PT 66272A PT 197766272 A PT197766272 A PT 197766272A PT 6627277 A PT6627277 A PT 6627277A PT 66272 A PT66272 A PT 66272A
Authority
PT
Portugal
Prior art keywords
isomers
alkyl
substd
phenylalkyl
corresp
Prior art date
Application number
PT197766272A
Other languages
English (en)
French (fr)
Other versions
PT66272B (fr
Original Assignee
Squibb E R & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/664,795 external-priority patent/US4088815A/en
Priority claimed from US05/664,796 external-priority patent/US4088816A/en
Priority claimed from US05/764,134 external-priority patent/US4127716A/en
Application filed by Squibb E R & Sons Inc filed Critical Squibb E R & Sons Inc
Publication of PT66272A publication Critical patent/PT66272A/pt
Publication of PT66272B publication Critical patent/PT66272B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT66272A 1976-03-08 1977-03-07 Procede pour la preparation de 3-heterotiomethyl ureide cephalosporines PT66272B (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/664,795 US4088815A (en) 1974-09-20 1976-03-08 3-Heterothio-7-ureido cephalosporins
US05/664,796 US4088816A (en) 1974-09-20 1976-03-08 3-Heterothio substituted 7-(ureido-heteroacetyl) cephalosporins
US05/764,134 US4127716A (en) 1976-03-08 1977-02-02 3-heterothiomethyl ureido cephalosporins

Publications (2)

Publication Number Publication Date
PT66272A true PT66272A (en) 1977-03-31
PT66272B PT66272B (fr) 1978-08-08

Family

ID=27418117

Family Applications (1)

Application Number Title Priority Date Filing Date
PT66272A PT66272B (fr) 1976-03-08 1977-03-07 Procede pour la preparation de 3-heterotiomethyl ureide cephalosporines

Country Status (16)

Country Link
JP (1) JPS52108996A (pt)
AT (1) AT352876B (pt)
AU (1) AU2236777A (pt)
CA (1) CA1088517A (pt)
CS (1) CS191190B2 (pt)
DD (1) DD129793A5 (pt)
DE (1) DE2707812A1 (pt)
DK (1) DK97077A (pt)
ES (1) ES456591A1 (pt)
FR (1) FR2343745A2 (pt)
GB (1) GB1573786A (pt)
NL (1) NL7702405A (pt)
NZ (1) NZ183332A (pt)
PL (1) PL196501A1 (pt)
PT (1) PT66272B (pt)
SE (1) SE7702558L (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927534A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
JPS52108996A (en) 1977-09-12
CS191190B2 (en) 1979-06-29
AU2236777A (en) 1978-08-24
ES456591A1 (es) 1978-02-16
DE2707812A1 (de) 1977-09-15
DK97077A (da) 1977-09-09
CA1088517A (en) 1980-10-28
NL7702405A (nl) 1977-09-12
ATA155177A (de) 1979-03-15
PL196501A1 (pl) 1978-02-13
AT352876B (de) 1979-10-10
FR2343745A2 (fr) 1977-10-07
SE7702558L (sv) 1977-09-09
PT66272B (fr) 1978-08-08
NZ183332A (en) 1979-10-25
DD129793A5 (de) 1978-02-08
GB1573786A (en) 1980-08-28

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