CS191190B2 - Method of preparing l-isomers of 3-heterothiomethyl ureido-caphalosporins - Google Patents

Method of preparing l-isomers of 3-heterothiomethyl ureido-caphalosporins

Info

Publication number
CS191190B2
CS191190B2 CS771474A CS147477A CS191190B2 CS 191190 B2 CS191190 B2 CS 191190B2 CS 771474 A CS771474 A CS 771474A CS 147477 A CS147477 A CS 147477A CS 191190 B2 CS191190 B2 CS 191190B2
Authority
CS
Czechoslovakia
Prior art keywords
heterothiomethyl
caphalosporins
ureido
isomers
preparing
Prior art date
Application number
CS771474A
Other languages
Czech (cs)
Inventor
Hermann Breuer
Uwe D Treuner
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/664,795 external-priority patent/US4088815A/en
Priority claimed from US05/664,796 external-priority patent/US4088816A/en
Priority claimed from US05/764,134 external-priority patent/US4127716A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of CS191190B2 publication Critical patent/CS191190B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS771474A 1976-03-08 1977-03-04 Method of preparing l-isomers of 3-heterothiomethyl ureido-caphalosporins CS191190B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/664,795 US4088815A (en) 1974-09-20 1976-03-08 3-Heterothio-7-ureido cephalosporins
US05/664,796 US4088816A (en) 1974-09-20 1976-03-08 3-Heterothio substituted 7-(ureido-heteroacetyl) cephalosporins
US05/764,134 US4127716A (en) 1976-03-08 1977-02-02 3-heterothiomethyl ureido cephalosporins

Publications (1)

Publication Number Publication Date
CS191190B2 true CS191190B2 (en) 1979-06-29

Family

ID=27418117

Family Applications (1)

Application Number Title Priority Date Filing Date
CS771474A CS191190B2 (en) 1976-03-08 1977-03-04 Method of preparing l-isomers of 3-heterothiomethyl ureido-caphalosporins

Country Status (16)

Country Link
JP (1) JPS52108996A (en)
AT (1) AT352876B (en)
AU (1) AU2236777A (en)
CA (1) CA1088517A (en)
CS (1) CS191190B2 (en)
DD (1) DD129793A5 (en)
DE (1) DE2707812A1 (en)
DK (1) DK97077A (en)
ES (1) ES456591A1 (en)
FR (1) FR2343745A2 (en)
GB (1) GB1573786A (en)
NL (1) NL7702405A (en)
NZ (1) NZ183332A (en)
PL (1) PL196501A1 (en)
PT (1) PT66272B (en)
SE (1) SE7702558L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927534A1 (en) * 1979-07-07 1981-01-08 Bayer Ag OPTICALLY PURE HETEROCYCLIC AMINO ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

Also Published As

Publication number Publication date
GB1573786A (en) 1980-08-28
ATA155177A (en) 1979-03-15
NL7702405A (en) 1977-09-12
DE2707812A1 (en) 1977-09-15
JPS52108996A (en) 1977-09-12
ES456591A1 (en) 1978-02-16
PT66272A (en) 1977-03-31
NZ183332A (en) 1979-10-25
DK97077A (en) 1977-09-09
PT66272B (en) 1978-08-08
AT352876B (en) 1979-10-10
SE7702558L (en) 1977-09-09
PL196501A1 (en) 1978-02-13
DD129793A5 (en) 1978-02-08
FR2343745A2 (en) 1977-10-07
CA1088517A (en) 1980-10-28
AU2236777A (en) 1978-08-24

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