PT652943E - Células hematopoiéticas facilitadoras e seus usos - Google Patents
Células hematopoiéticas facilitadoras e seus usos Download PDFInfo
- Publication number
- PT652943E PT652943E PT93918173T PT93918173T PT652943E PT 652943 E PT652943 E PT 652943E PT 93918173 T PT93918173 T PT 93918173T PT 93918173 T PT93918173 T PT 93918173T PT 652943 E PT652943 E PT 652943E
- Authority
- PT
- Portugal
- Prior art keywords
- bone marrow
- cells
- marrow cells
- hematopoietic
- engraftment
- Prior art date
Links
- 230000003394 haemopoietic effect Effects 0.000 title abstract 3
- 230000000494 facilitatory effect Effects 0.000 title abstract 2
- 210000002798 bone marrow cell Anatomy 0.000 abstract 4
- 210000004027 cell Anatomy 0.000 abstract 3
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 2
- 210000000056 organ Anatomy 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 206010068051 Chimerism Diseases 0.000 abstract 1
- 208000009329 Graft vs Host Disease Diseases 0.000 abstract 1
- 206010061598 Immunodeficiency Diseases 0.000 abstract 1
- 208000029462 Immunodeficiency disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 230000005784 autoimmunity Effects 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000010322 bone marrow transplantation Methods 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 208000024908 graft versus host disease Diseases 0.000 abstract 1
- 230000007813 immunodeficiency Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 230000000998 lymphohematopoietic effect Effects 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/26—Universal/off- the- shelf cellular immunotherapy; Allogenic cells or means to avoid rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46433—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46434—Antigens related to induction of tolerance to non-self
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91198992A | 1992-07-10 | 1992-07-10 | |
| US99654492A | 1992-12-24 | 1992-12-24 | |
| US6931593A | 1993-05-28 | 1993-05-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT652943E true PT652943E (pt) | 2008-10-09 |
Family
ID=27371514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT93918173T PT652943E (pt) | 1992-07-10 | 1993-07-09 | Células hematopoiéticas facilitadoras e seus usos |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0652943B1 (pt) |
| JP (1) | JP3917652B2 (pt) |
| AT (1) | ATE399854T1 (pt) |
| AU (1) | AU688734B2 (pt) |
| CA (1) | CA2139877C (pt) |
| DE (1) | DE69334227D1 (pt) |
| DK (1) | DK0652943T3 (pt) |
| ES (1) | ES2309985T3 (pt) |
| HK (1) | HK1010739A1 (pt) |
| NZ (2) | NZ255039A (pt) |
| PT (1) | PT652943E (pt) |
| SG (1) | SG55145A1 (pt) |
| WO (1) | WO1994001534A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1522395A (en) * | 1994-01-05 | 1995-08-01 | University Of Pittsburgh | Monoclonal antibodies to antigens expressed by hematopoietic facilitatory cells |
| WO1996015227A1 (en) * | 1994-11-14 | 1996-05-23 | Novartis Ag | Methods of inducing cell death of primitive hematopoietic cells and compositions for induction thereof |
| EP1015043A1 (en) * | 1997-09-10 | 2000-07-05 | Emory University | Methods for inhibiting rejection of transplanted tissues by bone grafting |
| EP2626415A3 (en) | 2004-10-25 | 2014-04-16 | Cellerant Therapeutics, Inc. | Methods of expanding myeloid cell populations and uses thereof |
| EP1984491B1 (en) * | 2006-02-14 | 2016-12-07 | Cellerant Therapeutics, Inc. | Compositions for enhancing engraftment of hematopoietic stem cells |
| US8632768B2 (en) * | 2008-05-30 | 2014-01-21 | University Of Louisville Research Foundation, Inc. | Human facilitating cells |
| JP6401445B2 (ja) * | 2013-10-10 | 2018-10-10 | 国立大学法人 東京大学 | 造血幹細胞移植用の組合せ細胞製剤および生着促進剤並びにこれらの製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5061620A (en) * | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
| DK0667904T3 (da) * | 1991-11-05 | 2002-06-03 | Univ Leland Stanford Junior | Suppressor- og progenitor-celler |
-
1993
- 1993-07-09 SG SG1996007923A patent/SG55145A1/en unknown
- 1993-07-09 EP EP93918173A patent/EP0652943B1/en not_active Expired - Lifetime
- 1993-07-09 DE DE69334227T patent/DE69334227D1/de not_active Expired - Lifetime
- 1993-07-09 CA CA002139877A patent/CA2139877C/en not_active Expired - Lifetime
- 1993-07-09 AT AT93918173T patent/ATE399854T1/de active
- 1993-07-09 NZ NZ255039A patent/NZ255039A/en not_active IP Right Cessation
- 1993-07-09 ES ES93918173T patent/ES2309985T3/es not_active Expired - Lifetime
- 1993-07-09 PT PT93918173T patent/PT652943E/pt unknown
- 1993-07-09 DK DK93918173T patent/DK0652943T3/da active
- 1993-07-09 JP JP50354894A patent/JP3917652B2/ja not_active Expired - Lifetime
- 1993-07-09 AU AU47717/93A patent/AU688734B2/en not_active Expired
- 1993-07-09 WO PCT/US1993/006506 patent/WO1994001534A1/en active Application Filing
-
1995
- 1995-01-24 NZ NZ299935A patent/NZ299935A/en unknown
-
1998
- 1998-10-29 HK HK98111586A patent/HK1010739A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08500009A (ja) | 1996-01-09 |
| AU688734B2 (en) | 1998-03-19 |
| WO1994001534A1 (en) | 1994-01-20 |
| JP3917652B2 (ja) | 2007-05-23 |
| EP0652943A4 (en) | 1996-02-07 |
| EP0652943B1 (en) | 2008-07-02 |
| SG55145A1 (en) | 1998-12-21 |
| ATE399854T1 (de) | 2008-07-15 |
| NZ255039A (en) | 1997-03-24 |
| AU4771793A (en) | 1994-01-31 |
| CA2139877A1 (en) | 1994-01-20 |
| DK0652943T3 (da) | 2008-11-03 |
| ES2309985T3 (es) | 2008-12-16 |
| NZ299935A (en) | 2000-07-28 |
| EP0652943A1 (en) | 1995-05-17 |
| DE69334227D1 (de) | 2008-08-14 |
| CA2139877C (en) | 2006-09-19 |
| HK1010739A1 (en) | 1999-06-25 |
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