PT3821891T - Utilização de fk506 para o tratamento da hipertensão arterial pulmonar - Google Patents

Utilização de fk506 para o tratamento da hipertensão arterial pulmonar

Info

Publication number
PT3821891T
PT3821891T PT202111092T PT20211109T PT3821891T PT 3821891 T PT3821891 T PT 3821891T PT 202111092 T PT202111092 T PT 202111092T PT 20211109 T PT20211109 T PT 20211109T PT 3821891 T PT3821891 T PT 3821891T
Authority
PT
Portugal
Prior art keywords
treatment
arterial hypertension
pulmonary arterial
pulmonary
hypertension
Prior art date
Application number
PT202111092T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of PT3821891T publication Critical patent/PT3821891T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT202111092T 2011-05-02 2012-04-30 Utilização de fk506 para o tratamento da hipertensão arterial pulmonar PT3821891T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161481317P 2011-05-02 2011-05-02

Publications (1)

Publication Number Publication Date
PT3821891T true PT3821891T (pt) 2023-08-31

Family

ID=47108011

Family Applications (2)

Application Number Title Priority Date Filing Date
PT202111092T PT3821891T (pt) 2011-05-02 2012-04-30 Utilização de fk506 para o tratamento da hipertensão arterial pulmonar
PT127793545T PT2704711T (pt) 2011-05-02 2012-04-30 Utilização de fk506 para o tratamento da hipertensão arterial pulmonar

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT127793545T PT2704711T (pt) 2011-05-02 2012-04-30 Utilização de fk506 para o tratamento da hipertensão arterial pulmonar

Country Status (19)

Country Link
US (6) US9474745B2 (enExample)
EP (3) EP4279130A3 (enExample)
JP (1) JP6177765B2 (enExample)
AU (2) AU2012250974B9 (enExample)
CA (1) CA2834368C (enExample)
CY (1) CY1123900T1 (enExample)
DK (2) DK2704711T3 (enExample)
ES (2) ES2856173T3 (enExample)
FI (1) FI3821891T3 (enExample)
HR (1) HRP20210245T1 (enExample)
HU (1) HUE053229T2 (enExample)
LT (1) LT2704711T (enExample)
PL (1) PL2704711T3 (enExample)
PT (2) PT3821891T (enExample)
RS (1) RS61480B1 (enExample)
SI (1) SI2704711T1 (enExample)
SM (1) SMT202100085T1 (enExample)
WO (1) WO2012151153A1 (enExample)
ZA (1) ZA201307905B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2704711T3 (da) 2011-05-02 2021-02-22 Univ Leland Stanford Junior Anvendelse af fk506 til behandlingen af pulmonal arteriel hypertension
AU2016207046B2 (en) * 2015-01-13 2021-04-01 Vivus Llc Combination therapy for pulmonary hypertension
MX2017014301A (es) * 2015-05-08 2018-03-23 Vivus Inc Composiciones y metodos para el tratamiento o prevencion de hipertension pulmonar.
CN108070566A (zh) * 2015-08-05 2018-05-25 中国医学科学院基础医学研究所 肺动脉高压治疗药物的干细胞筛选模型及应用
ES2683921B1 (es) * 2017-03-28 2019-04-22 Univ Vigo Método para la determinación del pronóstico en sujetos diagnosticados con hipertensión arterial pulmonar
EP3624821A4 (en) * 2017-05-19 2021-01-20 The Board of Trustees of the Leland Stanford Junior University ENZASTAURIN AND FRAGILE HISTIDINTRIAD (FHIT) - ENHANCING AGENTS FOR TREATMENT OF PULMONAL HYPERTENSION
EP3773571A1 (en) 2018-03-28 2021-02-17 Georg-August-Universitaet Goettingen Stiftung Oeffentlichen Rechts, Universitaetsmedizin Prevention or treatment of chronic organ injury

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489335B2 (en) * 2000-02-18 2002-12-03 Gholam A. Peyman Treatment of ocular disease
US20050119330A1 (en) 2003-03-17 2005-06-02 Kao Peter N. Use of antiproliferative agents in the treatment and prevention of pulmonary proliferative vascular diseases
AU2007230964B2 (en) 2006-03-23 2012-07-19 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
FR2936060B1 (fr) * 2008-09-17 2010-11-19 Assist Publ Hopitaux De Paris Procede de diagnostic d'une sclerodermie systemique ou d'une hypertension arterielle pulmonaire.
MX2011004284A (es) * 2008-10-22 2011-06-21 Sam Amer & Co Inc Metodo para tratar la hipertension arterial pulmonar.
DK2704711T3 (da) 2011-05-02 2021-02-22 Univ Leland Stanford Junior Anvendelse af fk506 til behandlingen af pulmonal arteriel hypertension

Also Published As

Publication number Publication date
SMT202100085T1 (it) 2021-05-07
CA2834368C (en) 2020-02-18
ES2856173T3 (es) 2021-09-27
WO2012151153A1 (en) 2012-11-08
EP4279130A2 (en) 2023-11-22
LT2704711T (lt) 2021-04-26
EP2704711A4 (en) 2014-11-19
JP2014513121A (ja) 2014-05-29
HUE053229T2 (hu) 2021-06-28
US9474745B2 (en) 2016-10-25
EP3821891A1 (en) 2021-05-19
DK2704711T3 (da) 2021-02-22
CA2834368A1 (en) 2012-11-08
HRP20210245T1 (hr) 2021-04-02
AU2012250974B2 (en) 2017-05-04
US20170007585A1 (en) 2017-01-12
ZA201307905B (en) 2015-05-27
US20180185340A1 (en) 2018-07-05
US20220184042A1 (en) 2022-06-16
CY1123900T1 (el) 2022-05-27
EP3821891B1 (en) 2023-06-07
JP6177765B2 (ja) 2017-08-09
US20140135358A1 (en) 2014-05-15
ES2954905T3 (es) 2023-11-27
US12521379B2 (en) 2026-01-13
SI2704711T1 (sl) 2021-04-30
PL2704711T3 (pl) 2021-07-05
US20230404982A1 (en) 2023-12-21
AU2017210583A1 (en) 2017-08-24
DK3821891T3 (da) 2023-09-04
FI3821891T3 (fi) 2023-08-24
AU2012250974A1 (en) 2013-11-14
AU2017210583B2 (en) 2019-02-07
EP2704711B1 (en) 2020-12-02
US20190091208A1 (en) 2019-03-28
AU2012250974B9 (en) 2017-05-18
RS61480B1 (sr) 2021-03-31
EP2704711A1 (en) 2014-03-12
EP4279130A3 (en) 2024-02-21
PT2704711T (pt) 2021-03-02

Similar Documents

Publication Publication Date Title
AP3818A (en) Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
IL239025A0 (en) Treatment of lung disease
ZA201403795B (en) Formulations for the treatment of diabetes
IL225130A (en) Devices for treating blood vessels defects
EP2675458A4 (en) COMPOUNDS AND METHOD FOR TREATING BLOOD HIGH PRESSURE
IL228719A0 (en) parp inhibitors for the treatment of cipn
ZA201307905B (en) Use of fk506 for the treatment of pulmonary arterial hypertension
ZA201306613B (en) Combinations comprising macitentan for the treatment of glioblastoma multiforme
LT2872145T (lt) Sujungti benzazepinai tureto sindromui gydyti
PH12014501052A1 (en) Methods and compositions for the treatment of diabetes and related symptoms
IL228891A (en) 3-carboxylic salts-n-ethyl n, n-dimethylpropane-1-amine for use in the treatment of cardiovascular disease
GB201112806D0 (en) Use of epitopes inducing specific tolerance for the prevention of tissue rejection
GB201118269D0 (en) Treatment of cardiovascular disease
GB201107988D0 (en) Treatment of cardiovascular disease
ZA201307614B (en) Use of 3-carboxy-n-ethyl-n,n-dimethylpropan-1-aminium salts in the treatment of cardiovascular disease
IL228973A0 (en) Oxymetazoline for the treatment of anorectal disorders
GB201106981D0 (en) Compounds for the treatment of clostridium difficle-associated disease
GB201119533D0 (en) Compounds for the treatment of neoplasia
IL232294A0 (en) Preparations for the treatment of diabetes
HK1194970A (en) Parp inhibitors for the treatment of cipn
GB201219092D0 (en) Treatment of cardiovascular disease
FI20115180L (fi) Koostumus käytettäväksi sairauden hoidossa
GB201007977D0 (en) Treatment of cardiovascular disease
IL222594A0 (en) Combined treatment utilizing vb-201
IT1399731B1 (it) Procedimento per la realizzazione di monili