PT3765097T - Derivados de lys-c(o)-glu substituídos com 2-alcoxi-6-[18f]fluoronicotinoílo como sondas eficientes para imagiologia de tecidos que expressam psma - Google Patents
Derivados de lys-c(o)-glu substituídos com 2-alcoxi-6-[18f]fluoronicotinoílo como sondas eficientes para imagiologia de tecidos que expressam psmaInfo
- Publication number
- PT3765097T PT3765097T PT197104219T PT19710421T PT3765097T PT 3765097 T PT3765097 T PT 3765097T PT 197104219 T PT197104219 T PT 197104219T PT 19710421 T PT19710421 T PT 19710421T PT 3765097 T PT3765097 T PT 3765097T
- Authority
- PT
- Portugal
- Prior art keywords
- fluoronicotinoyl
- alkoxy
- imaging
- psma expressing
- expressing tissues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18162380 | 2018-03-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3765097T true PT3765097T (pt) | 2022-06-01 |
Family
ID=61691391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT197104219T PT3765097T (pt) | 2018-03-16 | 2019-03-15 | Derivados de lys-c(o)-glu substituídos com 2-alcoxi-6-[18f]fluoronicotinoílo como sondas eficientes para imagiologia de tecidos que expressam psma |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11542234B2 (pt) |
| EP (1) | EP3765097B1 (pt) |
| DK (1) | DK3765097T3 (pt) |
| ES (1) | ES2914986T3 (pt) |
| HR (1) | HRP20220671T1 (pt) |
| HU (1) | HUE059482T2 (pt) |
| PL (1) | PL3765097T3 (pt) |
| PT (1) | PT3765097T (pt) |
| WO (1) | WO2019175405A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7390188B2 (ja) | 2016-10-27 | 2023-12-01 | プロジェニクス ファーマシューティカルズ， インコーポレイテッド | 医用画像分析、決定サポートシステム、および関連するグラフィカルユーザインタフェース（ｇｕｉ）アプリケーションのためのネットワーク |
| WO2020144134A1 (en) | 2019-01-07 | 2020-07-16 | Exini Diagnostics Ab | Systems and methods for platform agnostic whole body image segmentation |
| US11534125B2 (en) | 2019-04-24 | 2022-12-27 | Progenies Pharmaceuticals, Inc. | Systems and methods for automated and interactive analysis of bone scan images for detection of metastases |
| US11564621B2 (en) | 2019-09-27 | 2023-01-31 | Progenies Pharmacenticals, Inc. | Systems and methods for artificial intelligence-based image analysis for cancer assessment |
| US11900597B2 (en) | 2019-09-27 | 2024-02-13 | Progenics Pharmaceuticals, Inc. | Systems and methods for artificial intelligence-based image analysis for cancer assessment |
| CN111253465A (zh) * | 2020-03-03 | 2020-06-09 | 复旦大学附属肿瘤医院 | 一种psma结合剂及其用途 |
| CN111548305B (zh) * | 2020-05-12 | 2021-08-31 | 北京师范大学 | 一种可用于靶向psma的喹啉类化合物及其制备方法 |
| US11721428B2 (en) | 2020-07-06 | 2023-08-08 | Exini Diagnostics Ab | Systems and methods for artificial intelligence-based image analysis for detection and characterization of lesions |
| CA3231578A1 (en) | 2021-10-08 | 2023-04-13 | Exini Diagnostics Ab | Systems and methods for automated identification and classification of lesions in local lymph and distant metastases |
| US20230410985A1 (en) | 2022-06-08 | 2023-12-21 | Exini Diagnostics Ab | Systems and methods for assessing disease burden and progression |
| CN115057801A (zh) * | 2022-07-08 | 2022-09-16 | 西南医科大学附属医院 | 一种f-18标记psma靶向pet探针及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012110860A1 (en) | 2011-02-17 | 2012-08-23 | Glenmark Pharmaceuticals S.A. | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS |
| ES2912753T3 (es) | 2014-08-24 | 2022-05-27 | Max Planck Gesellschaft Zur Foerderung Der Wss | Método para la producción de ésteres activos marcados con 18F y su aplicación ejemplificada por la preparación de un marcador de PET específico de PSMA |
| KR20230111272A (ko) * | 2016-06-10 | 2023-07-25 | 더 존스 홉킨스 유니버시티 | 방사성 표지된 전립선-특이적 막 항원(PSMA) 억제제[18F]DCFPyL의 개선된 합성 |
-
2019
- 2019-03-15 PT PT197104219T patent/PT3765097T/pt unknown
- 2019-03-15 EP EP19710421.9A patent/EP3765097B1/en active Active
- 2019-03-15 ES ES19710421T patent/ES2914986T3/es active Active
- 2019-03-15 HR HRP20220671TT patent/HRP20220671T1/hr unknown
- 2019-03-15 HU HUE19710421A patent/HUE059482T2/hu unknown
- 2019-03-15 DK DK19710421.9T patent/DK3765097T3/da active
- 2019-03-15 US US16/981,456 patent/US11542234B2/en active Active
- 2019-03-15 PL PL19710421.9T patent/PL3765097T3/pl unknown
- 2019-03-15 WO PCT/EP2019/056578 patent/WO2019175405A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019175405A1 (en) | 2019-09-19 |
| ES2914986T3 (es) | 2022-06-20 |
| HUE059482T2 (hu) | 2022-11-28 |
| EP3765097A1 (en) | 2021-01-20 |
| US11542234B2 (en) | 2023-01-03 |
| EP3765097B1 (en) | 2022-04-27 |
| HRP20220671T1 (hr) | 2022-09-02 |
| PL3765097T3 (pl) | 2022-08-22 |
| US20210032206A1 (en) | 2021-02-04 |
| DK3765097T3 (da) | 2022-05-23 |
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