PT3643704T - Novos intermediários para a preparação de hidrocloreto de remifentanil - Google Patents
Novos intermediários para a preparação de hidrocloreto de remifentanilInfo
- Publication number
- PT3643704T PT3643704T PT182028787T PT18202878T PT3643704T PT 3643704 T PT3643704 T PT 3643704T PT 182028787 T PT182028787 T PT 182028787T PT 18202878 T PT18202878 T PT 18202878T PT 3643704 T PT3643704 T PT 3643704T
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- new intermediates
- remifentanil hydrochloride
- remifentanil
- hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/98—Nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18202878.7A EP3643704B1 (en) | 2018-10-26 | 2018-10-26 | New intermediates for the preparation of remifentanil hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3643704T true PT3643704T (pt) | 2021-03-08 |
Family
ID=64051418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT182028787T PT3643704T (pt) | 2018-10-26 | 2018-10-26 | Novos intermediários para a preparação de hidrocloreto de remifentanil |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10844014B2 (pt) |
| EP (1) | EP3643704B1 (pt) |
| DK (1) | DK3643704T3 (pt) |
| ES (1) | ES2858404T3 (pt) |
| HR (1) | HRP20210376T1 (pt) |
| PL (1) | PL3643704T3 (pt) |
| PT (1) | PT3643704T (pt) |
| RS (1) | RS61517B1 (pt) |
| SI (1) | SI3643704T1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202010168D0 (en) * | 2020-07-02 | 2020-08-19 | Johnson Matthey Plc | Process for preparing remifentanil hydrochloride |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5019583A (en) | 1989-02-15 | 1991-05-28 | Glaxo Inc. | N-phenyl-N-(4-piperidinyl)amides useful as analgesics |
| JP2009515960A (ja) | 2005-11-17 | 2009-04-16 | マリンクロッド・インコーポレイテッド | レミフェンタニルの合成方法 |
| AU2007208438A1 (en) | 2006-01-24 | 2007-08-02 | Mallinckrodt Inc. | Process for synthesizing remifentanil |
| EP1867635A1 (en) * | 2006-06-15 | 2007-12-19 | Kern Pharma, S.L. | Process for preparing remifentanil, intermediates thereof, use of said intermediates and processes for their preparation |
| US8299258B2 (en) | 2008-11-04 | 2012-10-30 | Cambrex Charles City | Method of making piperidine derivatives |
-
2018
- 2018-10-26 RS RS20210271A patent/RS61517B1/sr unknown
- 2018-10-26 EP EP18202878.7A patent/EP3643704B1/en active Active
- 2018-10-26 SI SI201830231T patent/SI3643704T1/sl unknown
- 2018-10-26 PL PL18202878T patent/PL3643704T3/pl unknown
- 2018-10-26 PT PT182028787T patent/PT3643704T/pt unknown
- 2018-10-26 ES ES18202878T patent/ES2858404T3/es active Active
- 2018-10-26 DK DK18202878.7T patent/DK3643704T3/da active
-
2019
- 2019-10-25 US US16/664,464 patent/US10844014B2/en active Active
-
2021
- 2021-03-03 HR HRP20210376TT patent/HRP20210376T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3643704B1 (en) | 2020-12-16 |
| HRP20210376T1 (hr) | 2021-04-16 |
| US10844014B2 (en) | 2020-11-24 |
| RS61517B1 (sr) | 2021-03-31 |
| ES2858404T3 (es) | 2021-09-30 |
| PL3643704T3 (pl) | 2021-06-14 |
| DK3643704T3 (da) | 2021-03-15 |
| EP3643704A1 (en) | 2020-04-29 |
| US20200131127A1 (en) | 2020-04-30 |
| SI3643704T1 (sl) | 2021-04-30 |
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