PT3643704T - Novos intermediários para a preparação de hidrocloreto de remifentanil - Google Patents

Novos intermediários para a preparação de hidrocloreto de remifentanil

Info

Publication number
PT3643704T
PT3643704T PT182028787T PT18202878T PT3643704T PT 3643704 T PT3643704 T PT 3643704T PT 182028787 T PT182028787 T PT 182028787T PT 18202878 T PT18202878 T PT 18202878T PT 3643704 T PT3643704 T PT 3643704T
Authority
PT
Portugal
Prior art keywords
preparation
new intermediates
remifentanil hydrochloride
remifentanil
hydrochloride
Prior art date
Application number
PT182028787T
Other languages
English (en)
Original Assignee
Hameln Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hameln Pharma Gmbh filed Critical Hameln Pharma Gmbh
Publication of PT3643704T publication Critical patent/PT3643704T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/98Nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT182028787T 2018-10-26 2018-10-26 Novos intermediários para a preparação de hidrocloreto de remifentanil PT3643704T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18202878.7A EP3643704B1 (en) 2018-10-26 2018-10-26 New intermediates for the preparation of remifentanil hydrochloride

Publications (1)

Publication Number Publication Date
PT3643704T true PT3643704T (pt) 2021-03-08

Family

ID=64051418

Family Applications (1)

Application Number Title Priority Date Filing Date
PT182028787T PT3643704T (pt) 2018-10-26 2018-10-26 Novos intermediários para a preparação de hidrocloreto de remifentanil

Country Status (9)

Country Link
US (1) US10844014B2 (pt)
EP (1) EP3643704B1 (pt)
DK (1) DK3643704T3 (pt)
ES (1) ES2858404T3 (pt)
HR (1) HRP20210376T1 (pt)
PL (1) PL3643704T3 (pt)
PT (1) PT3643704T (pt)
RS (1) RS61517B1 (pt)
SI (1) SI3643704T1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202010168D0 (en) * 2020-07-02 2020-08-19 Johnson Matthey Plc Process for preparing remifentanil hydrochloride

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019583A (en) 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
WO2007061555A1 (en) 2005-11-17 2007-05-31 Mallinckrodt Inc. Process for synthesizing remifentanil
EP1984336A2 (en) 2006-01-24 2008-10-29 Mallinckrodt, Inc. Process for synthesizing remifentanil
EP1867635A1 (en) * 2006-06-15 2007-12-19 Kern Pharma, S.L. Process for preparing remifentanil, intermediates thereof, use of said intermediates and processes for their preparation
WO2010053944A1 (en) 2008-11-04 2010-05-14 Cambrex Charles City, Inc. Improved method of making piperidine derivatives

Also Published As

Publication number Publication date
SI3643704T1 (sl) 2021-04-30
PL3643704T3 (pl) 2021-06-14
EP3643704A1 (en) 2020-04-29
EP3643704B1 (en) 2020-12-16
US10844014B2 (en) 2020-11-24
ES2858404T3 (es) 2021-09-30
DK3643704T3 (da) 2021-03-15
RS61517B1 (sr) 2021-03-31
US20200131127A1 (en) 2020-04-30
HRP20210376T1 (hr) 2021-04-16

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