PT3484907T - Novos análogos de cobertura fosfotriazol da extremidade 5' de marn, composição compreendendo os mesmos, molécula de arn incorporando os mesmos, suas utilizações e método de síntese de molécula de arn, proteína ou péptido - Google Patents

Novos análogos de cobertura fosfotriazol da extremidade 5' de marn, composição compreendendo os mesmos, molécula de arn incorporando os mesmos, suas utilizações e método de síntese de molécula de arn, proteína ou péptido

Info

Publication number
PT3484907T
PT3484907T PT177544822T PT17754482T PT3484907T PT 3484907 T PT3484907 T PT 3484907T PT 177544822 T PT177544822 T PT 177544822T PT 17754482 T PT17754482 T PT 17754482T PT 3484907 T PT3484907 T PT 3484907T
Authority
PT
Portugal
Prior art keywords
same
rna molecule
phosphotriazole
mrna
peptide
Prior art date
Application number
PT177544822T
Other languages
English (en)
Original Assignee
Univ Warszawski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Warszawski filed Critical Univ Warszawski
Publication of PT3484907T publication Critical patent/PT3484907T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PT177544822T 2016-07-16 2017-07-12 Novos análogos de cobertura fosfotriazol da extremidade 5' de marn, composição compreendendo os mesmos, molécula de arn incorporando os mesmos, suas utilizações e método de síntese de molécula de arn, proteína ou péptido PT3484907T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL417980A PL417980A1 (pl) 2016-07-16 2016-07-16 Nowe fosfotriazolowe analogi kapu końca 5' mRNA, kompozycja je zawierająca, cząsteczka RNA je zawierająca, ich zastosowania i sposób syntezy cząsteczki RNA, białka i peptydu

Publications (1)

Publication Number Publication Date
PT3484907T true PT3484907T (pt) 2020-09-17

Family

ID=59656110

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177544822T PT3484907T (pt) 2016-07-16 2017-07-12 Novos análogos de cobertura fosfotriazol da extremidade 5' de marn, composição compreendendo os mesmos, molécula de arn incorporando os mesmos, suas utilizações e método de síntese de molécula de arn, proteína ou péptido

Country Status (13)

Country Link
US (1) US10696709B2 (pt)
EP (1) EP3484907B1 (pt)
CY (1) CY1123516T1 (pt)
DK (1) DK3484907T3 (pt)
ES (1) ES2820242T3 (pt)
HR (1) HRP20201274T1 (pt)
HU (1) HUE051312T2 (pt)
LT (1) LT3484907T (pt)
PL (2) PL417980A1 (pt)
PT (1) PT3484907T (pt)
RS (1) RS60848B1 (pt)
SI (1) SI3484907T1 (pt)
WO (1) WO2018015845A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023250528A1 (en) * 2022-06-24 2023-12-28 The Broad Institute, Inc. Compositions and methods for preparing capped circular rna molecules

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8969545B2 (en) 2011-10-18 2015-03-03 Life Technologies Corporation Alkynyl-derivatized cap analogs, preparation and uses thereof

Also Published As

Publication number Publication date
PL417980A1 (pl) 2018-01-29
LT3484907T (lt) 2020-09-10
RS60848B1 (sr) 2020-10-30
US20200055891A1 (en) 2020-02-20
EP3484907B1 (en) 2020-05-13
HUE051312T2 (hu) 2021-03-01
PL3484907T3 (pl) 2021-02-08
HRP20201274T1 (hr) 2020-12-11
SI3484907T1 (sl) 2020-12-31
DK3484907T3 (da) 2020-08-17
ES2820242T3 (es) 2021-04-20
EP3484907A1 (en) 2019-05-22
WO2018015845A1 (en) 2018-01-25
US10696709B2 (en) 2020-06-30
CY1123516T1 (el) 2022-03-24

Similar Documents

Publication Publication Date Title
IL256395B (en) Stabilized antimicrobial peptides, preparations containing them and methods of producing them
SG11202008225PA (en) Novel rsv rna molecules and compositions for vaccination
WO2017024317A3 (en) Methods to induce targeted protein degradation through bifunctional molecules
PH12018501355A1 (en) Rsv f protein mutants
IL290633A (en) 5'-cyclophosphonate modified nucleotides, preparations containing them and their uses
HK1243424A1 (zh) 4'-硫代核苷的新型化合物及其製備方法、藥物組合物和應用
WO2016149455A3 (en) The rna interactome of polycomb repressive complex 1 (prc1)
WO2015006747A3 (en) Compositions comprising synthetic polynucleotides encoding crispr related proteins and synthetic sgrnas and methods of use
WO2016033315A3 (en) Synthon formation
WO2016205531A3 (en) Anti-her2 antibodies and methods of use
WO2016065349A8 (en) Short non-coding protein regulatory rnas (sprrnas) and methods of use
WO2012017324A3 (en) Combination pharmaceutical composition and methods of treating diseases or conditions associated with neurodegenerative diseases
EP4103577A4 (en) NOVEL 5' END CAP ANALOGS OF MRNA, RNA MOLECULE INCORPORATING THEM, USES THEREOF AND METHODS OF SYNTHESIS OF RNA MOLECULE OR PEPTIDE
WO2015011694A3 (en) Isotopologues of smad7 antisense oligonucleotides
PL3408276T3 (pl) 5’-tiofosforanowe analogi końca 5’ mRNA (kapu), mRNA je zawierające, sposób ich otrzymywania i zastosowania
EP3560950A4 (en) NOVEL MUTANT OF ALFA-CONOTOXIN-PEPTIDE-TXID, PHARMACEUTICAL COMPOSITION AND USE OF IT
WO2018226992A8 (en) Tau aggregation inhibitors
EP4103578A4 (en) NOVEL MRINA 5'-END-CAP ANALOGS MODIFIED IN THE PHOSPHATE RESIDUE, RNA MOLECULES CONTAINING SAME, THEIR USE AND METHOD FOR SYNTHESIS OF RNA MOLECULES OR PEPTIDES
WO2016020882A3 (en) Angiopoetin-like 4 (angptl4) antibodies and methods of use
PH12017500156A1 (en) Angiopoietin-like 4 antibodies and methods of use
WO2017007886A3 (en) Compositions for inhibiting dux4 gene expression and uses thereof
WO2012054907A3 (en) Novel hemagglutinin 5 (h5) proteins for the treatment and prevention of influenza infections
SG11202106327QA (en) Oligomeric nucleic acid molecule and application thereof
WO2016036635A8 (en) Chromobacterium subtsugae genes
PL3484907T3 (pl) Nowe fosfotriazolowe analogi kapu końca 5’ mRNA, kompozycja je zawierająca, cząsteczka RNA je zawierająca, ich zastosowania i sposób syntezy cząsteczki RNA, białka i peptydu