PT3120839T - Processo não mecânico para a micronização da digoxina - Google Patents

Processo não mecânico para a micronização da digoxina

Info

Publication number
PT3120839T
PT3120839T PT15178009T PT15178009T PT3120839T PT 3120839 T PT3120839 T PT 3120839T PT 15178009 T PT15178009 T PT 15178009T PT 15178009 T PT15178009 T PT 15178009T PT 3120839 T PT3120839 T PT 3120839T
Authority
PT
Portugal
Prior art keywords
micronization
digoxin
mechanical process
mechanical
Prior art date
Application number
PT15178009T
Other languages
English (en)
Inventor
Mehta Raman
Original Assignee
Mehta Raman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mehta Raman filed Critical Mehta Raman
Publication of PT3120839T publication Critical patent/PT3120839T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Steroid Compounds (AREA)
PT15178009T 2015-07-23 2015-07-23 Processo não mecânico para a micronização da digoxina PT3120839T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15178009.5A EP3120839B1 (en) 2015-07-23 2015-07-23 Non-mechanical process for the micronization of digoxin

Publications (1)

Publication Number Publication Date
PT3120839T true PT3120839T (pt) 2019-03-25

Family

ID=54010825

Family Applications (2)

Application Number Title Priority Date Filing Date
PT15178009T PT3120839T (pt) 2015-07-23 2015-07-23 Processo não mecânico para a micronização da digoxina
PT167543164T PT3324942T (pt) 2015-07-23 2016-07-21 Processo não-mecânico para a micronização da digoxina

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT167543164T PT3324942T (pt) 2015-07-23 2016-07-21 Processo não-mecânico para a micronização da digoxina

Country Status (12)

Country Link
US (1) US20180207099A1 (pt)
EP (2) EP3120839B1 (pt)
JP (1) JP6814522B2 (pt)
KR (1) KR20180032587A (pt)
CN (1) CN108024963A (pt)
AU (1) AU2016296162B2 (pt)
ES (2) ES2716681T3 (pt)
HU (2) HUE042420T2 (pt)
MX (1) MX365906B (pt)
PL (2) PL3120839T3 (pt)
PT (2) PT3120839T (pt)
WO (1) WO2017013485A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111110632B (zh) * 2018-10-31 2023-01-20 上海上药信谊药厂有限公司 一种地高辛气雾剂及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3643760A1 (de) * 1986-12-20 1988-06-23 Boehringer Mannheim Gmbh Verfahren zur anreicherung und/oder isolierung von herzglykosiden unter verwendung unpolarer adsorberharze
US7105178B2 (en) 2001-07-17 2006-09-12 Sun Pharmaceutical Industries Limited Cardiotonic composition
CN101390838A (zh) * 2008-10-10 2009-03-25 北京工业大学 一种制备微粉化药物的方法

Also Published As

Publication number Publication date
PL3324942T3 (pl) 2020-05-18
PL3120839T3 (pl) 2019-08-30
ES2765675T3 (es) 2020-06-10
EP3120839A1 (en) 2017-01-25
PT3324942T (pt) 2020-01-17
AU2016296162A1 (en) 2018-02-01
ES2716681T3 (es) 2019-06-14
EP3324942A1 (en) 2018-05-30
MX2018001010A (es) 2018-05-17
CN108024963A (zh) 2018-05-11
US20180207099A1 (en) 2018-07-26
MX365906B (es) 2019-06-18
KR20180032587A (ko) 2018-03-30
HUE048065T2 (hu) 2020-05-28
HUE042420T2 (hu) 2019-07-29
WO2017013485A1 (en) 2017-01-26
EP3120839B1 (en) 2018-12-19
BR112018001204A2 (pt) 2018-09-11
AU2016296162B2 (en) 2021-03-18
JP6814522B2 (ja) 2021-01-20
JP2018521073A (ja) 2018-08-02
EP3324942B1 (en) 2019-10-30

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