PT3064573T - Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into neuron - Google Patents

Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into neuron

Info

Publication number
PT3064573T
PT3064573T PT138967591T PT13896759T PT3064573T PT 3064573 T PT3064573 T PT 3064573T PT 138967591 T PT138967591 T PT 138967591T PT 13896759 T PT13896759 T PT 13896759T PT 3064573 T PT3064573 T PT 3064573T
Authority
PT
Portugal
Prior art keywords
stem cell
neuron
differentiating pluripotent
induced
mesenchymal stem
Prior art date
Application number
PT138967591T
Other languages
Portuguese (pt)
Original Assignee
Bbhc Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bbhc Co Ltd filed Critical Bbhc Co Ltd
Publication of PT3064573T publication Critical patent/PT3064573T/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/76—Undefined extracts from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1369—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from blood-borne mesenchymal stem cells, e.g. MSC from umbilical blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
PT138967591T 2013-11-01 2013-11-05 Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into neuron PT3064573T (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020130132056A KR101542847B1 (en) 2013-11-01 2013-11-01 Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Neuron

Publications (1)

Publication Number Publication Date
PT3064573T true PT3064573T (en) 2020-04-02

Family

ID=53004392

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138967591T PT3064573T (en) 2013-11-01 2013-11-05 Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into neuron

Country Status (17)

Country Link
US (1) US10000735B2 (en)
EP (1) EP3064573B1 (en)
JP (1) JP6711759B2 (en)
KR (1) KR101542847B1 (en)
CN (1) CN105683360B (en)
AU (1) AU2013403887B2 (en)
CY (1) CY1122954T1 (en)
DK (1) DK3064573T3 (en)
ES (1) ES2776182T3 (en)
HR (1) HRP20200475T1 (en)
HU (1) HUE048803T2 (en)
LT (1) LT3064573T (en)
PL (1) PL3064573T3 (en)
PT (1) PT3064573T (en)
RS (1) RS60147B1 (en)
SI (1) SI3064573T1 (en)
WO (1) WO2015064804A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3064572T (en) 2013-11-01 2020-07-27 Bbhc Co. Ltd. Method for producing induced pluripotent stem cell from mesenchymal stem cell and induced pluripotent stem cell produced by the method
KR101699761B1 (en) * 2014-05-23 2017-01-25 주식회사 비비에이치씨 Method for Preparing Induced Pluripotency Stem Cell from Mesenchymal Stem Cell Using Phlorotannin Fraction
KR101592401B1 (en) * 2014-06-13 2016-02-05 주식회사 비비에이치씨 Method for Preparing patient-specific Induced Pluripotency Stem Cell from adipose-derived Mesenchymal Stem Cell and Production thereof
KR20170024940A (en) 2015-08-26 2017-03-08 조선대학교산학협력단 Pretreatment culture medium for promoting the differentiation of mesenchymal stem cells into neurons, Method of promoting the differentiation of mesenchymal stem cells into neurons using the same
CN105907705B (en) * 2016-06-28 2020-01-24 广州市搏克生物技术有限公司 Pluripotent stem cell culture medium
CN106479977B (en) * 2016-08-29 2018-02-23 广东依浦赛生物科技有限公司 People source iPS stem cell in vitro directed differentiation is the kit and method of nerve cell
CN111004778A (en) * 2019-12-16 2020-04-14 江苏艾洛特生物科技有限公司 Cell serum-free culture medium additive, culture medium and application
CN114990065A (en) * 2022-05-16 2022-09-02 康妍葆(北京)干细胞科技有限公司 Directional inducer of neural stem cells, induction method and application

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7998460B2 (en) * 2003-04-17 2011-08-16 The Board Of Trustees Of The Leland Stanford Junior University Prevention of deficits in neurogenesis with anti-inflammatory agents
CN103146649B (en) * 2004-06-09 2018-05-22 爱丁堡大学管理处 Neural stem cell
WO2008066630A2 (en) 2006-10-27 2008-06-05 Caritas St. Elizabeth Medical Center Of Boston, Inc. Methods for reprogramming adult somatic cells and uses thereof
KR101016761B1 (en) 2009-02-26 2011-02-25 부경대학교 산학협력단 Ecklonia cava Kjellman extracts having skin whitening activity
JP2012210154A (en) * 2009-08-03 2012-11-01 Keio Gijuku Method for establishing differentiated cell-originated pluripotent stem cell
WO2011037301A1 (en) * 2009-09-22 2011-03-31 서울대학교병원 Method for derivation of pluripotent stem cells from adult cells and pluripotent stem cells produced by method
KR101548616B1 (en) * 2010-02-18 2015-09-01 연세대학교 산학협력단 Method of Inducing Mesenchymal Stem Cell to Differentiate into GABAergic Neuronal Cell and Compostion Comprising BDNF for Inducing Differentiation into GABAergic Neuronal Cell
KR20120002134A (en) * 2010-06-30 2012-01-05 서울대학교산학협력단 Method for dedifferentiations of adipose tissue stromal cells
CN101914493B (en) * 2010-07-16 2012-07-04 山东省齐鲁干细胞工程有限公司 Inducing method for differentiating umbilical cord mesenchymal stem cells into nerve cells
KR20120040488A (en) 2010-10-19 2012-04-27 충남대학교산학협력단 Cosmetic compositions containing phlorotannins from ecklonia stolonifera and ecklonia cave extract
KR101887956B1 (en) 2011-08-10 2018-08-13 (주)아모레퍼시픽 Composition for skin lightening comprising extract of Ecklonia cava treated by enzyme

Also Published As

Publication number Publication date
LT3064573T (en) 2020-06-10
KR101542847B1 (en) 2015-08-10
CY1122954T1 (en) 2021-10-29
KR20150050862A (en) 2015-05-11
US10000735B2 (en) 2018-06-19
EP3064573A4 (en) 2017-09-06
RS60147B1 (en) 2020-05-29
DK3064573T3 (en) 2020-03-23
CN105683360A (en) 2016-06-15
EP3064573A1 (en) 2016-09-07
JP2016540521A (en) 2016-12-28
EP3064573B1 (en) 2020-02-26
AU2013403887B2 (en) 2018-04-05
ES2776182T3 (en) 2020-07-29
US20160272939A1 (en) 2016-09-22
HRP20200475T1 (en) 2020-10-02
CN105683360B (en) 2020-12-11
PL3064573T3 (en) 2020-08-10
HUE048803T2 (en) 2020-08-28
AU2013403887A1 (en) 2016-06-23
SI3064573T1 (en) 2020-07-31
WO2015064804A1 (en) 2015-05-07
JP6711759B2 (en) 2020-06-17

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