PT2718714E - Marcadores para a cicatrização deficiente de fraturas ósseas - Google Patents

Marcadores para a cicatrização deficiente de fraturas ósseas Download PDF

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Publication number
PT2718714E
PT2718714E PT127329944T PT12732994T PT2718714E PT 2718714 E PT2718714 E PT 2718714E PT 127329944 T PT127329944 T PT 127329944T PT 12732994 T PT12732994 T PT 12732994T PT 2718714 E PT2718714 E PT 2718714E
Authority
PT
Portugal
Prior art keywords
markers
bone fracture
fracture healing
impaired bone
impaired
Prior art date
Application number
PT127329944T
Other languages
English (en)
Inventor
Enrico Bastianelli
Xavier Pesesse
Valérie Gangji
Jean-Philippe Hauzeur
Dominique De Seny
Myrielle Mathieu
Aude Ingels
Sabrina Rigutto
Delphine Spruyt
Valentina Albarani
Michel Malaise
Original Assignee
Bone Therapeutics Sa
Universitã Libre De Bruxelles
Université de Liège
Ct Hospitalier Universitaire De Liã Ge
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bone Therapeutics Sa, Universitã Libre De Bruxelles, Université de Liège, Ct Hospitalier Universitaire De Liã Ge filed Critical Bone Therapeutics Sa
Publication of PT2718714E publication Critical patent/PT2718714E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/5421IL-8
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
PT127329944T 2011-06-10 2012-06-11 Marcadores para a cicatrização deficiente de fraturas ósseas PT2718714E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11169591 2011-06-10

Publications (1)

Publication Number Publication Date
PT2718714E true PT2718714E (pt) 2015-10-22

Family

ID=46466430

Family Applications (1)

Application Number Title Priority Date Filing Date
PT127329944T PT2718714E (pt) 2011-06-10 2012-06-11 Marcadores para a cicatrização deficiente de fraturas ósseas

Country Status (12)

Country Link
US (1) US20140100137A1 (pt)
EP (1) EP2718714B1 (pt)
JP (1) JP2014519610A (pt)
AU (1) AU2012266241B2 (pt)
BE (1) BE1021759B1 (pt)
CA (1) CA2838480A1 (pt)
DK (1) DK2718714T3 (pt)
ES (1) ES2548268T3 (pt)
HK (1) HK1194140A1 (pt)
PL (1) PL2718714T3 (pt)
PT (1) PT2718714E (pt)
WO (1) WO2012168482A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3033617A4 (en) * 2013-08-12 2017-04-05 Health Research, Inc. Biomarkers for prostate cancer
WO2016126844A1 (en) * 2015-02-03 2016-08-11 The Trustees Of The University Of Pennsylvania Novel methods for early identification of bone healing ability in injured patients

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
WO2007107003A1 (en) * 2006-03-22 2007-09-27 Osteopharm Inc. Markers for the diagnosis, monitoring and prognosis of osteoporosis and for assessing the risk for osteoporosis and for osteoporotic fractures
US8983570B2 (en) * 2007-03-27 2015-03-17 Cardiovascular Biotherapeutics, Inc. Therapeutic angiogenesis for treatment of the spine

Also Published As

Publication number Publication date
HK1194140A1 (en) 2014-10-10
EP2718714B1 (en) 2015-07-29
WO2012168482A1 (en) 2012-12-13
EP2718714A1 (en) 2014-04-16
US20140100137A1 (en) 2014-04-10
PL2718714T3 (pl) 2015-12-31
AU2012266241B2 (en) 2016-04-28
ES2548268T3 (es) 2015-10-15
BE1021759B1 (fr) 2016-01-15
JP2014519610A (ja) 2014-08-14
DK2718714T3 (en) 2015-09-28
CA2838480A1 (en) 2012-12-13
AU2012266241A1 (en) 2014-01-09

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