PT2539328E - Derivados de furoxano solúveis em água com uma atividade antitumoral - Google Patents
Derivados de furoxano solúveis em água com uma atividade antitumoral Download PDFInfo
- Publication number
- PT2539328E PT2539328E PT117116665T PT11711666T PT2539328E PT 2539328 E PT2539328 E PT 2539328E PT 117116665 T PT117116665 T PT 117116665T PT 11711666 T PT11711666 T PT 11711666T PT 2539328 E PT2539328 E PT 2539328E
- Authority
- PT
- Portugal
- Prior art keywords
- water soluble
- antitumor activity
- furoxan
- derivatives
- furoxan derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/08—1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A000287A IT1398522B1 (it) | 2010-02-23 | 2010-02-23 | Nuovi derivati furossanici idrosolubili aventi attivita' antitumorale. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2539328E true PT2539328E (pt) | 2014-11-05 |
Family
ID=42676615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT117116665T PT2539328E (pt) | 2010-02-23 | 2011-02-23 | Derivados de furoxano solúveis em água com uma atividade antitumoral |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8946271B2 (pt) |
| EP (1) | EP2539328B1 (pt) |
| DK (1) | DK2539328T3 (pt) |
| ES (1) | ES2522841T3 (pt) |
| IT (1) | IT1398522B1 (pt) |
| PT (1) | PT2539328E (pt) |
| WO (1) | WO2011104671A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013271378A1 (en) | 2012-06-07 | 2014-12-18 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the inhibition of Pin1 |
| WO2016011265A2 (en) | 2014-07-17 | 2016-01-21 | Beth Israel Deaconess Medical Center, Inc. | Biomarkers for pin1-associated disorders |
| WO2016145186A1 (en) | 2015-03-12 | 2016-09-15 | Beth Israel Deaconess Medical Center, Inc. | Enhanced atra-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE485261T1 (de) * | 2005-11-23 | 2010-11-15 | Nicox Sa | Salicylsäurederivate |
| WO2010081488A1 (en) * | 2009-01-15 | 2010-07-22 | Humanitas Mirasole S.P.A. | Nitric oxide furoxan derivative compounds endowed with antitumoral activity |
-
2010
- 2010-02-23 IT ITMI2010A000287A patent/IT1398522B1/it active
-
2011
- 2011-02-23 DK DK11711666.5T patent/DK2539328T3/da active
- 2011-02-23 WO PCT/IB2011/050743 patent/WO2011104671A1/en active Application Filing
- 2011-02-23 ES ES11711666.5T patent/ES2522841T3/es active Active
- 2011-02-23 EP EP11711666.5A patent/EP2539328B1/en not_active Not-in-force
- 2011-02-23 PT PT117116665T patent/PT2539328E/pt unknown
- 2011-02-23 US US13/522,026 patent/US8946271B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2539328A1 (en) | 2013-01-02 |
| US8946271B2 (en) | 2015-02-03 |
| DK2539328T3 (da) | 2014-11-03 |
| ITMI20100287A1 (it) | 2011-08-24 |
| WO2011104671A1 (en) | 2011-09-01 |
| IT1398522B1 (it) | 2013-03-01 |
| US20130035360A1 (en) | 2013-02-07 |
| EP2539328B1 (en) | 2014-07-30 |
| ES2522841T3 (es) | 2014-11-18 |
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