PT2459175T - Novo processo de granulação e o granulado assim preparado - Google Patents
Novo processo de granulação e o granulado assim preparadoInfo
- Publication number
- PT2459175T PT2459175T PT107153389T PT10715338T PT2459175T PT 2459175 T PT2459175 T PT 2459175T PT 107153389 T PT107153389 T PT 107153389T PT 10715338 T PT10715338 T PT 10715338T PT 2459175 T PT2459175 T PT 2459175T
- Authority
- PT
- Portugal
- Prior art keywords
- granulating process
- prepared granulate
- new granulating
- new
- granulate
- Prior art date
Links
- 239000008187 granular material Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0900468A HU0900468D0 (en) | 2009-07-28 | 2009-07-28 | Novel granulation process and granulates therefrom |
| HU1000044A HU230900B1 (en) | 2010-01-25 | 2010-01-25 | New granulating process and the granulates prepared by this |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2459175T true PT2459175T (pt) | 2018-02-07 |
Family
ID=89989520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT107153389T PT2459175T (pt) | 2009-07-28 | 2010-02-24 | Novo processo de granulação e o granulado assim preparado |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8927021B2 (pt) |
| EP (1) | EP2459175B1 (pt) |
| BR (1) | BR112012002069B8 (pt) |
| EA (1) | EA027578B1 (pt) |
| ES (1) | ES2657708T3 (pt) |
| HU (1) | HUE038048T2 (pt) |
| PL (1) | PL2459175T3 (pt) |
| PT (1) | PT2459175T (pt) |
| WO (1) | WO2011012912A2 (pt) |
| ZA (1) | ZA201200795B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU231036B1 (hu) * | 2013-09-30 | 2019-12-30 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Koleszterin bioszintézis gátló hatóanyagot és koleszterin abszorpciót gátló hatóanyagot tartalmazó kombinációs gyógyszerkészítmény |
| KR101977785B1 (ko) * | 2014-06-25 | 2019-05-14 | 한미약품 주식회사 | 에제티미브 및 로수바스타틴을 포함하는 경구용 복합제제 및 그 제조방법 |
| EP3243506A1 (en) * | 2016-05-09 | 2017-11-15 | Adamed sp. z o.o. | Pharmaceutical composition |
| CZ2016539A3 (cs) * | 2016-09-05 | 2018-03-14 | Zentiva, K.S. | Farmaceutická kompozice obsahující dvě rozdílné účinné látky a způsob její přípravy |
| CZ2016538A3 (cs) * | 2016-09-05 | 2018-03-14 | Zentiva, K.S. | Farmaceutická kompozice obsahující dvě rozdílné účinné látky |
| GR1010183B (el) * | 2020-12-14 | 2022-03-01 | Elpen Αε Φαρμακευτικη Βιομηχανια, | Στερεες φαρμακοτεχνικες μορφες ατορβαστατινης και εζετιμιμπης |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060160785A1 (en) | 2004-12-03 | 2006-07-20 | Judith Aronhime | Ezetimibe polymorphs |
| CN101938995A (zh) * | 2007-12-17 | 2011-01-05 | 克卡制药新梅斯托股份公司 | 包含非微粉化依泽替米贝微粒的悬浮液 |
-
2010
- 2010-02-24 EA EA201290055A patent/EA027578B1/ru not_active IP Right Cessation
- 2010-02-24 EP EP10715338.9A patent/EP2459175B1/en active Active
- 2010-02-24 WO PCT/HU2010/000022 patent/WO2011012912A2/en active Application Filing
- 2010-02-24 PL PL10715338T patent/PL2459175T3/pl unknown
- 2010-02-24 BR BR112012002069A patent/BR112012002069B8/pt active IP Right Grant
- 2010-02-24 HU HUE10715338A patent/HUE038048T2/hu unknown
- 2010-02-24 ES ES10715338.9T patent/ES2657708T3/es active Active
- 2010-02-24 US US13/387,239 patent/US8927021B2/en active Active
- 2010-02-24 PT PT107153389T patent/PT2459175T/pt unknown
-
2012
- 2012-02-01 ZA ZA2012/00795A patent/ZA201200795B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2657708T3 (es) | 2018-03-06 |
| WO2011012912A3 (en) | 2011-12-08 |
| BR112012002069B1 (pt) | 2020-12-01 |
| EP2459175A2 (en) | 2012-06-06 |
| BR112012002069A2 (pt) | 2016-05-31 |
| US8927021B2 (en) | 2015-01-06 |
| EA027578B1 (ru) | 2017-08-31 |
| US20120164227A1 (en) | 2012-06-28 |
| ZA201200795B (en) | 2013-05-29 |
| PL2459175T3 (pl) | 2018-04-30 |
| EP2459175B1 (en) | 2017-11-01 |
| WO2011012912A2 (en) | 2011-02-03 |
| HUE038048T2 (hu) | 2018-09-28 |
| BR112012002069B8 (pt) | 2021-05-25 |
| EA201290055A1 (ru) | 2012-06-29 |
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