PT2301532E - Utilização de estatinas como anticonvulsivantes, antiepilépticos e neuroprotectores - Google Patents

Utilização de estatinas como anticonvulsivantes, antiepilépticos e neuroprotectores Download PDF

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Publication number
PT2301532E
PT2301532E PT97576540T PT09757654T PT2301532E PT 2301532 E PT2301532 E PT 2301532E PT 97576540 T PT97576540 T PT 97576540T PT 09757654 T PT09757654 T PT 09757654T PT 2301532 E PT2301532 E PT 2301532E
Authority
PT
Portugal
Prior art keywords
neuroprotectors
antiepileptics
anticonvulsants
statins
Prior art date
Application number
PT97576540T
Other languages
English (en)
Original Assignee
Neuron Biopharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuron Biopharma Sa filed Critical Neuron Biopharma Sa
Publication of PT2301532E publication Critical patent/PT2301532E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT97576540T 2008-06-03 2009-06-03 Utilização de estatinas como anticonvulsivantes, antiepilépticos e neuroprotectores PT2301532E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200801733A ES2330184B1 (es) 2008-06-03 2008-06-03 Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores.

Publications (1)

Publication Number Publication Date
PT2301532E true PT2301532E (pt) 2015-02-04

Family

ID=41328842

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97576540T PT2301532E (pt) 2008-06-03 2009-06-03 Utilização de estatinas como anticonvulsivantes, antiepilépticos e neuroprotectores

Country Status (7)

Country Link
US (1) US8927599B2 (pt)
EP (1) EP2301532B1 (pt)
DK (1) DK2301532T3 (pt)
ES (2) ES2330184B1 (pt)
PL (1) PL2301532T3 (pt)
PT (1) PT2301532E (pt)
WO (1) WO2009147275A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2344826B1 (es) * 2009-03-06 2011-06-06 Neuron Biopharma, S.A. Compuestos neuroprotectores.
ES2380473B1 (es) * 2010-10-13 2013-02-19 Neuron Biopharma, S.A. Compuesto neuroprotector, hipocolesterolémico, antiinflamatorio y antiepiléptico.
WO2012054724A1 (en) * 2010-10-21 2012-04-26 Massachusetts Institute Of Technology Methods of treating seizure disorders
WO2014210538A1 (en) * 2013-06-28 2014-12-31 The Regents Of The University Of California Treating cognitive deficits associated with noonan syndrome

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (pt) 1974-06-07 1981-03-18
US4231938A (en) 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
AU548996B2 (en) 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
MX7065E (es) 1980-06-06 1987-04-10 Sankyo Co Un procedimiento microbiologico para preparar derivados de ml-236b
WO1984002131A1 (en) 1982-11-22 1984-06-07 Sandoz Ag Analogs of mevalolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
NO177005C (no) 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
US6080778A (en) * 1998-03-23 2000-06-27 Children's Medical Center Corporation Methods for decreasing beta amyloid protein
US6472421B1 (en) * 1998-11-13 2002-10-29 Nymox Corporation Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor
US7323496B2 (en) * 1999-11-08 2008-01-29 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US8519005B2 (en) * 2000-07-27 2013-08-27 Thomas N. Thomas Compositions and methods to prevent toxicity of antiinflammatory agents and enhance their efficacy
CA2548313A1 (en) * 2003-12-23 2005-07-14 Musc Foundation For Research Development Methods and compositions for the prevention and treatment of inflammatory diseases or conditions
JP2007534699A (ja) * 2004-04-26 2007-11-29 アルコン，インコーポレイティド 高眼圧症及び緑内障の治療ためのスタチン
BRPI0706757A2 (pt) * 2006-01-30 2011-04-05 Israel Ben David Bryson composições e métodos para tratar pacientes com doença cardiovascular, cerebrovascular e outra doença vascular

Also Published As

Publication number Publication date
EP2301532B1 (en) 2014-10-29
PL2301532T3 (pl) 2015-04-30
EP2301532A1 (en) 2011-03-30
ES2330184B1 (es) 2010-07-05
EP2301532A4 (en) 2013-01-23
DK2301532T3 (en) 2015-01-12
ES2528212T3 (es) 2015-02-05
US8927599B2 (en) 2015-01-06
US20110184056A1 (en) 2011-07-28
WO2009147275A1 (es) 2009-12-10
ES2330184A1 (es) 2009-12-04

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